Umbilical Cord Mesenchymal Stem Cells Conditioned Medium Promotes Aβ25-35 phagocytosis by Modulating Autophagy and Aβ-Degrading Enzymes in BV2 Cells

Resveratrol promotes hUC-MSCs engraftment and neural repair in a mouse model of Alzheimer’s disease

(2018) Xinxin Wang et al.   BEHAVIOURAL BRAIN RESEARCH

Recent advances in the neurobiology and neuropharmacology of Alzheimer’s disease

(2018) Kushal Kumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease

(2018) Daniel J. Colacurcio et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mesenchymal Stem Cell-Derived Extracellular Vesicles Suppresses iNOS Expression and Ameliorates Neural Impairment in Alzheimer’s Disease Mice

(2018) Shan-Shan Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer’s Disease: From Firing Instability to Homeostasis Network Collapse

(2018) Samuel Frere et al.   NEURON

Microglia and Neonatal Brain Injury

(2018) Carina Mallard et al.   NEUROSCIENCE

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

(2017) Ainhoa Plaza-Zabala et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

(2017) Mariana A. de Godoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

(2017) Lauren S. Whyte et al.   JOURNAL OF NEUROCHEMISTRY

Soluble TREM2 in CSF sheds light on microglial activation in AD

(2017) Heather Wood   Nature Reviews Neurology

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

Extracellular Vesicles in Brain Tumors and Neurodegenerative Diseases

(2017) Federica Ciregia et al.   Frontiers in Molecular Neuroscience

Assays to Monitor Autophagy Progression in Cell Cultures

(2017) Idil Orhon et al.   Cells

The endocytic pathway in microglia during health, aging and Alzheimer’s disease

(2016) Santiago Solé-Domènech et al.   AGEING RESEARCH REVIEWS

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

(2016) Elizabeth E. Spangenberg et al.   BRAIN

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model

(2016) Jared Ehrhart et al.   CELL TRANSPLANTATION

Autophagy and Alzheimer’s Disease

(2016) Qian Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Microglia in Alzheimer's Disease: The Good, the Bad and the Ugly

(2016) Dario Tejera et al.   Current Alzheimer Research

Targeting microglia for the treatment of Alzheimer's Disease

(2016) Paul D. Wes et al.   GLIA

Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model

(2016) Sung Hoon Baik et al.   GLIA

Stem cell therapy for Alzheimer's disease: hope or hype?

(2016) Selina Wray et al.   LANCET NEUROLOGY

Accelerating stem cell trials for Alzheimer's disease

(2016) Joshua G Hunsberger et al.   LANCET NEUROLOGY

Stem Cell Therapy: A Prospective Treatment for Alzheimer's Disease

(2016) Ji Han Lee et al.   Psychiatry Investigation

Differential Clearance of Rat and Human Bone Marrow-Derived Mesenchymal Stem Cells from the Brain after Intra-arterial Infusion in Rats

(2015) Joonas Khabbal et al.   CELL TRANSPLANTATION

An Aβ42 uptake and degradation via Rg3 requires an activation of caveolin, clathrin and Aβ-degrading enzymes in microglia

(2015) Su Kil Jang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Human umbilical cord mesenchymal stem cells: an overview of their potential in cell-based therapy

(2015) Tan Li et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

(2015) Nabil N. Dagher et al.   Journal of Neuroinflammation

LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells

(2015) Peidu Jiang et al.   METHODS

GDF-15 Secreted from Human Umbilical Cord Blood Mesenchymal Stem Cells Delivered Through the Cerebrospinal Fluid Promotes Hippocampal Neurogenesis and Synaptic Activity in an Alzheimer's Disease Model

(2015) Dong Hyun Kim et al.   STEM CELLS AND DEVELOPMENT

Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems

(2015) Ari Waisman et al.   TRENDS IN IMMUNOLOGY

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis

(2014) Michela Guglielmotto et al.   Autophagy

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome

(2014) Mi-Hyang Cho et al.   Autophagy

Microglial Aβ Receptors in Alzheimer’s Disease

(2014) Yang Yu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Mesenchymal Stem Cells Can Prevent Alterations in Behavior and Neurogenesis Induced by Aß25–35 Administration

(2014) Keren Nicole Hamisha et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models

(2013) Jin Young Shin et al.   Autophagy

Conditioned Medium from Bone Marrow-Derived Mesenchymal Stem Cells Improves Recovery after Spinal Cord Injury in Rats: An Original Strategy to Avoid Cell Transplantation

(2013) Dorothée Cantinieaux et al.   PLoS One

Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

(2013) Dan Frenkel et al.   Nature Communications

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-β plaques

(2011) J-Y Kim et al.   CELL DEATH AND DIFFERENTIATION

Aβ-Degrading Enzymes: Potential for Treatment of Alzheimer Disease

(2011) James Scott Miners et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A reporter cell system to monitor autophagy based on p62/SQSTM1

(2010) Kenneth Bowitz Larsen et al.   Autophagy

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

(2010) Dun-Sheng Yang et al.   BRAIN

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease

(2010) Hyun Ju Lee et al.   NEUROSCIENCE LETTERS

Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of disease-specific biomarkers

(2010) Paul Dowling et al.   PROTEOMICS

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE