Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
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Title
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
Authors
Keywords
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Journal
BRAIN
Volume 134, Issue 1, Pages 258-277
Publisher
Oxford University Press (OUP)
Online
2010-12-24
DOI
10.1093/brain/awq341
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Note: Only part of the references are listed.- Neurodegenerative lysosomal disorders: A continuum from development to late age
- (2014) Ralph A. Nixon et al. Autophagy
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- (2010) Belen Tizon et al. PLoS One
- Amyloid β and impairment in multiple memory systems in older transgenic APP TgCRND8 mice
- (2009) A. Hanna et al. GENES BRAIN AND BEHAVIOR
- Interaction between Oligomers of Stefin B and Amyloid-βin Vitroand in Cells
- (2009) Katja Škerget et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?
- (2009) Boris Turk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cystatin B Deficiency Sensitizes Neurons to Oxidative Stress in Progressive Myoclonus Epilepsy, EPM1
- (2009) M. K. Lehtinen et al. JOURNAL OF NEUROSCIENCE
- Autophagy regulates lipid metabolism
- (2009) Rajat Singh et al. NATURE
- Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition
- (2009) Y. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chaperone-mediated autophagy: selectivity pays off
- (2009) Ana Maria Cuervo TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice
- (2008) Ditte Zerlang Christensen et al. ACTA NEUROPATHOLOGICA
- Size and morphology of toxic oligomers of amyloidogenic proteins: a case study of human stefin B
- (2008) Slavko Čeru et al. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Autophagy and multivesicular bodies: two closely related partners
- (2008) C M Fader et al. CELL DEATH AND DIFFERENTIATION
- Cystatins: Biochemical and structural properties, and medical relevance
- (2008) ">Vito Turk Frontiers in Bioscience-Landmark
- Activation of the Amyloid Cascade in Apolipoprotein E4 Transgenic Mice Induces Lysosomal Activation and Neurodegeneration Resulting in Marked Cognitive Deficits
- (2008) H. Belinson et al. JOURNAL OF NEUROSCIENCE
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
- (2008) B. Boland et al. JOURNAL OF NEUROSCIENCE
- Small molecule enhancers of autophagy for neurodegenerative diseases
- (2008) Sovan Sarkar et al. Molecular BioSystems
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model
- (2008) Ryoichi Kimura et al. NEUROBIOLOGY OF DISEASE
- Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease
- (2008) Binggui Sun et al. NEURON
- Cystatin B and its EPM1 mutants are polymeric and aggregate prone in vivo
- (2007) Elena Cipollini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Molecular background of EPM1—Unverricht–Lundborg disease
- (2007) Tarja Joensuu et al. EPILEPSIA
- The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
- (2007) John et al. Frontiers in Bioscience-Landmark
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