Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Inhibition of amyloid-beta peptide aggregation rescues the autophagic deficits in the TgCRND8 mouse model of Alzheimer disease

(2012) Aaron Y. Lai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-  Precursor Protein

(2012) C. Parr et al.   MOLECULAR AND CELLULAR BIOLOGY

Soluble CCL5 Derived from Bone Marrow-Derived Mesenchymal Stem Cells and Activated by Amyloid β Ameliorates Alzheimer's Disease in Mice by Recruiting Bone Marrow-Induced Microglia Immune Responses

(2012) Jong Kil Lee et al.   STEM CELLS

Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy

(2011) SooYeon Lee et al.   Autophagy

Activation of autophagy in mesenchymal stem cells provides tumor stromal support

(2011) Cecilia G. Sanchez et al.   CARCINOGENESIS

Autophagy failure in Alzheimer's disease—locating the primary defect

(2011) Ralph A. Nixon et al.   NEUROBIOLOGY OF DISEASE

Oncosuppressive Functions of Autophagy

(2010) Eugenia Morselli et al.   ANTIOXIDANTS & REDOX SIGNALING

HMGB1: A novel Beclin 1-binding protein active in autophagy

(2010) Rui Kang et al.   Autophagy

Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

(2010) Ju-Hyun Lee et al.   CELL

Neuroprotective Effect of Human Mesenchymal Stem Cells in an Animal Model of Double Toxin-Induced Multiple System Atrophy Parkinsonism

(2010) Hyun-Jung Park et al.   CELL TRANSPLANTATION

Galectin-3 secreted by human umbilical cord blood-derived mesenchymal stem cells reduces amyloid-β42 neurotoxicity in vitro

(2010) Ju-Yeon Kim et al.   FEBS LETTERS

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau

(2010) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies

(2010) Deborah A. Ryan et al.   JOURNAL OF NEUROSCIENCE METHODS

Immunohistochemical evidence for macroautophagy in neurones and endothelial cells in Alzheimer's disease

(2010) J.-F. Ma et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

(2010) M. M. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The expression ofbeclin 1is associated with favorable prognosis in stage IIIB colon cancers

(2009) Bao-Xiu Li et al.   Autophagy

Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway

(2009) Narasimman Gurusamy et al.   CARDIOVASCULAR RESEARCH

A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

(2009) Jianrong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Alzheimer's disease genetic mutation evokes ultrastructural alterations: Correlation to an intracellular Aβ deposition and the level of GSK-3β-P(Y216) phosphorylated form

(2009) Beata Pajak et al.   NEUROTOXICOLOGY

Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila

(2009) Daijun Ling et al.   PLoS One

Chaperone-mediated autophagy: selectivity pays off

(2009) Ana Maria Cuervo   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson’s disease

(2008) Hyun Jung Park et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE