Tetramethylpyrazine protects against high glucose-induced vascular smooth muscle cell injury through inhibiting the phosphorylation of JNK, p38MAPK, and ERK

Mechanism of Generation of Oxidative Stress and Pathophysiology of Type 2 Diabetes Mellitus: How Are They Interlinked?

(2017) Kanwal Rehman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations

(2017) Wael M Abdel-Rahman et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Oxidative stress-induced mitochondrial dysfunction in a normal colon epithelial cell line

(2017) Nandakumar Packiriswamy et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The source of circulating selenoprotein S and its association with type 2 diabetes mellitus and atherosclerosis: a preliminary study

(2016) Shan-shan Yu et al.   Cardiovascular Diabetology

Prescription of oral hypoglycemic agents for patients with type 2 diabetes mellitus: A retrospective cohort study using a Japanese hospital database

(2016) Makito Tanabe et al.   Journal of Diabetes Investigation

Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2

(2016) Weijing Feng et al.   Oncotarget

Cardiovascular Actions and Therapeutic Potential of Tetramethylpyrazine (Active Component Isolated fromRhizoma Chuanxiong): Roles and Mechanisms

(2016) Ming Guo et al.   Biomed Research International

Angiotensin-(1–7) abrogates angiotensin II-induced proliferation, migration and inflammation in VSMCs through inactivation of ROS-mediated PI3K/Akt and MAPK/ERK signaling pathways

(2016) Feng Zhang et al.   Scientific Reports

Liraglutide attenuates high glucose-induced abnormal cell migration, proliferation, and apoptosis of vascular smooth muscle cells by activating the GLP-1 receptor, and inhibiting ERK1/2 and PI3K/Akt signaling pathways

(2015) Lili Shi et al.   Cardiovascular Diabetology

Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association

(2015) Caroline S. Fox et al.   DIABETES CARE

Molecular Pathways Regulating Macrovascular Pathology and Vascular Smooth Muscle Cells Phenotype in Type 2 Diabetes

(2015) Sara Casella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endoplasmic Reticulum Stress-Mediated Apoptosis Contributing to High Glucose-Induced Vascular Smooth Muscle Cell Calcification

(2015) Qiang Zhu et al.   JOURNAL OF VASCULAR RESEARCH

The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats

(2015) Jianzhong Hu et al.   NEUROCHEMICAL RESEARCH

Potentials of incretin-based therapies in dementia and stroke in type 2 diabetes mellitus

(2015) Onno N Groeneveld et al.   Journal of Diabetes Investigation

Emodin Inhibits Homocysteine-Induced C-Reactive Protein Generation in Vascular Smooth Muscle Cells by Regulating PPARγ Expression and ROS-ERK1/2/p38 Signal Pathway

(2015) Xiaoming Pang et al.   PLoS One

Brain structural changes and their correlation with vascular disease in type 2 diabetes mellitus patients: a voxel-based morphometric study

(2014) Huaijun Liu et al.   Neural Regeneration Research

Artemisinin attenuates plantlet-derived growth factor BB-induced migration of vascular smooth muscle cells

(2014) Kang Pa Lee et al.   Nutrition Research and Practice

Tetramethylpyrazine Ameliorates High Glucose-Induced Endothelial Dysfunction by Increasing Mitochondrial Biogenesis

(2014) Qiong Xu et al.   PLoS One

Tetramethylpyrazine Suppresses Transient Oxygen-Glucose Deprivation-Induced Connexin32 Expression and Cell Apoptosis via the ERK1/2 and p38 MAPK Pathway in Cultured Hippocampal Neurons

(2014) Gu Gong et al.   PLoS One

Biomechanical regulation of vascular smooth muscle cell functions: from in vitro to in vivo understanding

(2013) J. Qiu et al.   Journal of the Royal Society Interface

Evaluation of Antioxidant and Immunity Function of Tetramethylpyrazine Phosphate Tablets in Vivo

(2012) Ling Guo et al.   MOLECULES

Phosphodiesterase 3A (PDE3A) Deletion Suppresses Proliferation of Cultured Murine Vascular Smooth Muscle Cells (VSMCs) via Inhibition of Mitogen-activated Protein Kinase (MAPK) Signaling and Alterations in Critical Cell Cycle Regulatory Proteins

(2011) Najma Begum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tetramethylpyrazine Inhibits Hypoxia-Induced Pulmonary Vascular Leakage in Rats via the ROS-HIF-VEGF Pathway

(2011) Le Zhang et al.   PHARMACOLOGY

Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II

(2010) Xia Xue et al.   INVESTIGATIONAL NEW DRUGS

Stabilization of mitochondrial function by tetramethylpyrazine protects against kainate-induced oxidative lesions in the rat hippocampus

(2009) Shu-Yan Li et al.   FREE RADICAL BIOLOGY AND MEDICINE