Angiotensin-(1–7) abrogates angiotensin II-induced proliferation, migration and inflammation in VSMCs through inactivation of ROS-mediated PI3K/Akt and MAPK/ERK signaling pathways

Salusin-β contributes to vascular remodeling associated with hypertension via promoting vascular smooth muscle cell proliferation and vascular fibrosis

(2015) Hai-Jian Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

PGC-1  limits angiotensin II-induced rat vascular smooth muscle cells proliferation via attenuating NOX1-mediated generation of reactive oxygen species

(2015) Q. Zhao et al.   BIOSCIENCE REPORTS

Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway

(2015) Kang Ding et al.   BMC Complementary and Alternative Medicine

Angiotensin-(1–7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice

(2015) Yixuan Shi et al.   CLINICAL SCIENCE

The renin–angiotensin system and its involvement in vascular disease

(2015) Bibi S. van Thiel et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Angiotensin II-induced hypertensive renal inflammation is mediated through HMGB1-TLR4 signaling in rat tubulo-epithelial cells

(2015) Anand R. Nair et al.   EXPERIMENTAL CELL RESEARCH

Angiotensin-(1–7) counteracts angiotensin II-induced dysfunction in cerebral endothelial cells via modulating Nox2/ROS and PI3K/NO pathways

(2015) Xiang Xiao et al.   EXPERIMENTAL CELL RESEARCH

Modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7

(2015) Li Ji et al.   JOURNAL OF HYPERTENSION

Angiotensin-(1-7) Prevents Angiotensin II-induced Fibrosis in Cremaster Microvessels

(2015) Kyle A. Carver et al.   MICROCIRCULATION

Angiotensin-(1–7) counteracts the effects of Ang II on vascular smooth muscle cells, vascular remodeling and hemorrhagic stroke: Role of the NFкB inflammatory pathway

(2015) Ji C. Bihl et al.   VASCULAR PHARMACOLOGY

Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways

(2015) Wenjin Hao et al.   Scientific Reports

Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways

(2015) Kosuke Nagayama et al.   PLoS One

Angiotensin-(1–7) abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2

(2014) Ebaa M. Alzayadneh et al.   CELLULAR SIGNALLING

Angiotensin II and Vascular Injury

(2014) Augusto C. Montezano et al.   CURRENT HYPERTENSION REPORTS

Leptin and Vascular Smooth Muscle Cells

(2014) Mariella Trovati et al.   CURRENT PHARMACEUTICAL DESIGN

Cardamonin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and migration by downregulating p38 MAPK, Akt, and ERK phosphorylation

(2014) Yan-Jing Shen et al.   Journal of Natural Medicines

Angiotensin-converting enzyme 2 and angiotensin 1–7: novel therapeutic targets

(2014) Fan Jiang et al.   Nature Reviews Cardiology

Sulfuretin inhibits 6-hydroxydopamine-induced neuronal cell death via reactive oxygen species-dependent mechanisms in human neuroblastoma SH-SY5Y cells

(2014) Seung-Hwan Kwon et al.   NEUROCHEMISTRY INTERNATIONAL

Deletion of angiotensin-converting enzyme 2 promotes the development of atherosclerosis and arterial neointima formation

(2013) Makoto Sahara et al.   CARDIOVASCULAR RESEARCH

Oral Formulation of Angiotensin-(1–7) Improves Lipid Metabolism and Prevents High-Fat Diet–Induced Hepatic Steatosis and Inflammation in Mice

(2013) John David Feltenberger et al.   HYPERTENSION

Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation

(2013) T. Bruder-Nascimento et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Magnolol attenuates neointima formation by inducing cell cycle arrest via inhibition of ERK1/2 and NF-κB activation in vascular smooth muscle cells

(2012) Rajendra Karki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles

(2012) P. Lacolley et al.   CARDIOVASCULAR RESEARCH

Activation of PPARδ counteracts angiotensin II-induced ROS generation by inhibiting rac1 translocation in vascular smooth muscle cells

(2012) Hanna Lee et al.   FREE RADICAL RESEARCH

ACE2 Deficiency Enhances Angiotensin II-Mediated Aortic Profilin-1 Expression, Inflammation and Peroxynitrite Production

(2012) Hai-Yan Jin et al.   PLoS One

AVE0991, a Nonpeptide Compound, Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation via Induction of Heme Oxygenase-1 and Downregulation of p-38 MAPK Phosphorylation

(2012) Chen Sheng-Long et al.   International Journal of Hypertension

Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species

(2011) Annet Kirabo et al.   CARDIOVASCULAR RESEARCH

Early Atheroma-Derived Agonists of Peroxisome Proliferator–Activated Receptor-γ Trigger Intramedial Angiogenesis in a Smooth Muscle Cell–Dependent Manner

(2011) Benoît Ho-Tin-Noé et al.   CIRCULATION RESEARCH

Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology

(2011) YanFei Qi et al.   EXPERIMENTAL PHYSIOLOGY

c-Src in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats

(2011) Ying Han et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by β3 integrin signaling

(2010) Manikandan Panchatcharam et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Superoxide anions in the paraventricular nucleus mediate the enhanced cardiac sympathetic afferent reflex and sympathetic activity in renovascular hypertensive rats

(2010) Ying Han et al.   JOURNAL OF APPLIED PHYSIOLOGY

Pravastatin Counteracts Angiotensin II-Induced Upregulation and Activation of NADPH Oxidase at Plasma Membrane of Human Endothelial Cells

(2010) Ezequiel Alvarez et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Casein-derived tripeptide Ile–Pro–Pro improves angiotensin-(1–7)- and bradykinin-induced rat mesenteric artery relaxation

(2010) Pauliina I. Ehlers et al.   LIFE SCIENCES

Different Effects of Angiotensin II and Angiotensin-(1-7) on Vascular Smooth Muscle Cell Proliferation and Migration

(2010) Feng Zhang et al.   PLoS One

NADPH oxidases and angiotensin II receptor signaling

(2008) Abel Martin Garrido et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Modulation by bradykinin and nitric oxide of angiotensin II-induced apoptosis in a vascular smooth muscle cell phenotype

(2007) S. Colie et al.   INTERNATIONAL IMMUNOPHARMACOLOGY