In Rheumatoid Arthritis, Synovitis at Different Inflammatory Sites Is Dominated by Shared but Patient-Specific T Cell Clones

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

(2017) Deepak A. Rao et al.   NATURE

Antigen-specific immunotherapies in rheumatic diseases

(2017) Judit Pozsgay et al.   Nature Reviews Rheumatology

TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis

(2016) Maura Rossetti et al.   ANNALS OF THE RHEUMATIC DISEASES

Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators

(2015) Isabelle Le Mercier et al.   Frontiers in Immunology

A circulating reservoir of pathogenic-like CD4+T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment

(2014) Roberto Spreafico et al.   ANNALS OF THE RHEUMATIC DISEASES

The effects of tocilizumab on osteitis, synovitis and erosion progression in rheumatoid arthritis: results from the ACT-RAY MRI substudy

(2014) Philip G Conaghan et al.   ANNALS OF THE RHEUMATIC DISEASES

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk

(2013) Annie Yarwood et al.   ANNALS OF THE RHEUMATIC DISEASES

Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients

(2013) S Kelly et al.   ANNALS OF THE RHEUMATIC DISEASES

Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity

(2013) M E Doorenspleet et al.   ANNALS OF THE RHEUMATIC DISEASES

How to perform and analyse synovial biopsies

(2013) Daniëlle M. Gerlag et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Features of the Synovium of Individuals at Risk of Developing Rheumatoid Arthritis: Implications for Understanding Preclinical Rheumatoid Arthritis

(2013) M. J. H. de Hair et al.   Arthritis & Rheumatology

Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease

(2012) P L Klarenbeek et al.   ANNALS OF THE RHEUMATIC DISEASES

Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets

(2011) Xinli Hu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Costimulatory Molecule CD27 Maintains Clonally Diverse CD8+ T Cell Responses of Low Antigen Affinity to Protect against Viral Variants

(2011) Klaas P.J.M. van Gisbergen et al.   IMMUNITY

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Human T-cell memory consists mainly of unexpanded clones

(2010) Paul L. Klarenbeek et al.   IMMUNOLOGY LETTERS

Alterations of the synovial T cell repertoire in anti-citrullinated protein antibody-positive rheumatoid arthritis

(2009) Tineke Cantaert et al.   ARTHRITIS AND RHEUMATISM

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The road to genome-wide association studies

(2008) Leonid Kruglyak   NATURE REVIEWS GENETICS