SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain–Dependent Immune Response in Mouse Bone Marrow–Derived Macrophages

Expression and regulation of proton-coupled oligopeptide transporters in colonic tissue and immune cells of mice

(2018) Yuqing Wang et al.   BIOCHEMICAL PHARMACOLOGY

Functional Characterization of Human Peptide/Histidine Transporter 1 in Stably Transfected MDCK Cells

(2018) Feifeng Song et al.   MOLECULAR PHARMACEUTICS

Targeting PEPT1: a novel strategy to improve the antitumor efficacy of doxorubicin in human hepatocellular carcinoma therapy

(2017) Yanxia Gong et al.   Oncotarget

Lysosomal solute carrier transporters gain momentum in research

(2016) B Bissa et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Intriguing possibilities and beneficial aspects of transporter-conscious drug design

(2015) Toshihiko Tashima   BIOORGANIC & MEDICINAL CHEMISTRY

NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease

(2014) Roberta Caruso et al.   IMMUNITY

Colonic Expression of the Peptide Transporter PEPT1 Is Downregulated During Intestinal Inflammation and Is Not Required for NOD2-dependent Immune Activation

(2014) Tilo Wuensch et al.   INFLAMMATORY BOWEL DISEASES

Divergent developmental expression and function of the proton-coupled oligopeptide transporters PepT2 and PhT1 in regional brain slices of mouse and rat

(2014) Yongjun Hu et al.   JOURNAL OF NEUROCHEMISTRY

Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1

(2014) Yongjun Hu et al.   MOLECULAR PHARMACEUTICS

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

(2014) Norihiro Nakamura et al.   NATURE

Prodrug Design Targeting Intestinal PepT1 for Improved Oral Absorption: Design and Performance

(2013) Youxi Zhang et al.   CURRENT DRUG METABOLISM

How do cells optimize luminal environments of endosomes/lysosomes for efficient inflammatory responses?

(2013) T. Kobayashi et al.   JOURNAL OF BIOCHEMISTRY

CNS drug targeting: have we travelled in right path?

(2013) Antony Deva Punitha et al.   JOURNAL OF DRUG TARGETING

PepT1 expressed in immune cells has an important role in promoting the immune response during experimentally induced colitis

(2013) Saravanan Ayyadurai et al.   LABORATORY INVESTIGATION

Proton-coupled oligopeptide transporter family SLC15: Physiological, pharmacological and pathological implications

(2013) David E. Smith et al.   MOLECULAR ASPECTS OF MEDICINE

Functional and Molecular Expression of the Proton-Coupled Oligopeptide Transporters in Spleen and Macrophages from Mouse and Human

(2013) Dongli Sun et al.   MOLECULAR PHARMACEUTICS

Impact of Intestinal PepT1 on the Kinetics and Dynamics of N-Formyl-Methionyl-Leucyl-Phenylalanine, a Bacterially-Produced Chemotactic Peptide

(2012) Shu-Pei Wu et al.   MOLECULAR PHARMACEUTICS

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

The PepT1–NOD2 Signaling Pathway Aggravates Induced Colitis in Mice

(2011) Guillaume Dalmasso et al.   GASTROENTEROLOGY

The Solute Carrier Family 15A4 Regulates TLR9 and NOD1 Functions in the Innate Immune System and Promotes Colitis in Mice

(2011) Shigemi Sasawatari et al.   GASTROENTEROLOGY

PepT1 mediates transport of the proinflammatory bacterial tripeptide l-Ala-γ-d-Glu-meso-DAP in intestinal epithelial cells

(2010) Guillaume Dalmasso et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Identification ofDrosophilaYin and PEPT2 as Evolutionarily Conserved Phagosome-associated Muramyl Dipeptide Transporters

(2010) Guillaume M. Charrière et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population

(2010) C-F. He et al.   LUPUS

pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling

(2009) Jooeun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clathrin- and Dynamin-Dependent Endocytic Pathway Regulates Muramyl Dipeptide Internalization and NOD2 Activation

(2009) N. Marina-Garcia et al.   JOURNAL OF IMMUNOLOGY

NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease

(2008) Grace Chen et al.   Annual Review of Pathology-Mechanisms of Disease

The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands

(2008) Yun-Gi Kim et al.   IMMUNITY

Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q

(2008) F. Takeuchi et al.   JOURNAL OF HUMAN GENETICS

Targeted Disruption of Peptide TransporterPept1Gene in Mice Significantly Reduces Dipeptide Absorption in Intestine

(2008) Yongun Hu et al.   MOLECULAR PHARMACEUTICS

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY