Th1, Th17, and Th1Th17 Lymphocytes during Tuberculosis: Th1 Lymphocytes Predominate and Appear as Low-Differentiated CXCR3+CCR6+Cells in the Blood and Highly Differentiated CXCR3+/−CCR6−Cells in the Lungs

Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells

(2017) Sharee A. Basdeo et al.   JOURNAL OF IMMUNOLOGY

Characterization ofMycobacterium tuberculosis–Specific Cells Using MHC Class II Tetramers Reveals Phenotypic Differences Related to HIV Infection and Tuberculosis Disease

(2017) Natalie Strickland et al.   JOURNAL OF IMMUNOLOGY

Neutrophils in Tuberculosis: Heterogeneity Shapes the Way?

(2017) Irina V. Lyadova   MEDIATORS OF INFLAMMATION

The introduction of mesenchymal stromal cells induces different immunological responses in the lungs of healthy and M. tuberculosis infected mice

(2017) Tatiana Nenasheva et al.   PLoS One

Severe Tuberculosis in Humans Correlates Best with Neutrophil Abundance and Lymphocyte Deficiency and Does Not Correlate with Antigen-Specific CD4 T-Cell Response

(2017) Alexander V. Panteleev et al.   Frontiers in Immunology

Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases

(2017) Bas C. Mourik et al.   Frontiers in Immunology

CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease

(2016) Shunsuke Sakai et al.   PLoS Pathogens

Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge

(2015) L Monin et al.   Mucosal Immunology

Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis

(2015) Stacey N. Harbour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BALB/c mice display more enhanced BCG vaccine induced Th1 and Th17 response than C57BL/6 mice but have equivalent protection

(2015) M. Carmen Garcia-Pelayo et al.   TUBERCULOSIS

Th17 cells in autoimmune diseases

(2015) Lei Han et al.   Frontiers of Medicine

Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids

(2014) Radha Ramesh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Chemokine Receptor CXCR3 Is Degraded following Internalization and Is Replenished at the Cell Surface by De Novo Synthesis of Receptor

(2014) A. Meiser et al.   JOURNAL OF IMMUNOLOGY

Distinct, Specific IL-17- and IL-22-Producing CD4+ T Cell Subsets Contribute to the Human Anti-Mycobacterial Immune Response

(2014) T. J. Scriba et al.   JOURNAL OF IMMUNOLOGY

IL-1  Promotes the Differentiation of Polyfunctional Human CCR6+CXCR3+ Th1/17 Cells That Are Specific for Pathogenic and Commensal Microbes

(2014) T. Duhen et al.   JOURNAL OF IMMUNOLOGY

Transcriptional Profile of Tuberculosis Antigen–Specific T Cells Reveals Novel Multifunctional Features

(2014) Cecilia Lindestam Arlehamn et al.   JOURNAL OF IMMUNOLOGY

Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity

(2014) Jacinta Bustamante et al.   SEMINARS IN IMMUNOLOGY

Unexpected Role for IL-17 in Protective Immunity against Hypervirulent Mycobacterium tuberculosis HN878 Infection

(2014) Radha Gopal et al.   PLoS Pathogens

Reverse Translation in Tuberculosis: Neutrophils Provide Clues for Understanding Development of Active Disease

(2014) Anca Dorhoi et al.   Frontiers in Immunology

Plasticity of Human CD4 T Cell Subsets

(2014) Jens Geginat et al.   Frontiers in Immunology

Prognostic values of serum IP-10 and IL-17 in Patients with Pulmonary Tuberculosis

(2013) Yung-Che Chen et al.   DISEASE MARKERS

Lack ofMycobacterium tuberculosis-specific interleukin-17A-producing CD4+T cells in active disease

(2013) Matthieu Perreau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3+CCR6+ Th1 Subset

(2013) Cecilia S. Lindestam Arlehamn et al.   PLoS Pathogens

Reduced Frequency of Memory T Cells and Increased Th17 Responses in Patients with Active Tuberculosis

(2012) Nancy D. Marín et al.   Clinical and Vaccine Immunology

Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells

(2012) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease

(2012) Javier O. Jurado et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mtb-Specific CD27low CD4 T Cells as Markers of Lung Tissue Destruction during Pulmonary Tuberculosis in Humans

(2012) Irina Yu Nikitina et al.   PLoS One

Altered T cell differentiation associated with loss of CD27 and CD28 in HIV infected Indian individuals

(2011) Kamalika Mojumdar et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

IL-23-dependent IL-17 drives Th1-cell responses followingMycobacterium bovisBCG vaccination

(2011) Radha Gopal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Outbreaks of Mycobacterium Tuberculosis MDR Strains Induce High IL-17 T-Cell Response in Patients With MDR Tuberculosis That Is Closely Associated With High Antigen Load

(2011) Juan I. Basile et al.   JOURNAL OF INFECTIOUS DISEASES

Recombinant BCG ΔureC hly+ Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses

(2011) Christiane Desel et al.   JOURNAL OF INFECTIOUS DISEASES

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

Neutrophils in tuberculosis: friend or foe?

(2011) David M. Lowe et al.   TRENDS IN IMMUNOLOGY

Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis

(2011) Kerryn Matthews et al.   TUBERCULOSIS

A Gamma Interferon Independent Mechanism of CD4 T Cell Mediated Control of M. tuberculosis Infection in vivo

(2011) Alena M. Gallegos et al.   PLoS Pathogens

Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

(2010) Benjamin M. N. Kagina et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Genetic proof for the transient nature of the Th17 phenotype

(2010) Florian C. Kurschus et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epigenetic Instability of Cytokine and Transcription Factor Gene Loci Underlies Plasticity of the T Helper 17 Cell Lineage

(2010) Ryuta Mukasa et al.   IMMUNITY

CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1-Mediated Inhibition

(2010) D. L. Barber et al.   JOURNAL OF IMMUNOLOGY

T-bet represses TH17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

(2010) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

Gene expression of IL17 and IL23 in the lungs of patients with active tuberculosis

(2008) K Dheda et al.   THORAX