Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

(2015) James G. Ryall et al.   Cell Stem Cell

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon

(2015) Wesley A Grimm et al.   GUT

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells

(2015) Myriam Catalano et al.   Molecular Oncology

Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism

(2015) Rushika M. Perera et al.   NATURE

Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation

(2015) G Grassi et al.   Cell Death & Disease

Autophagy suppresses melanoma tumorigenesis by inducing senescence

(2014) He Liu et al.   Autophagy

Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

(2014) Michelle Cicchini et al.   Autophagy

A new class of ubiquitin-Atg8 receptors involved in selective autophagy and polyQ protein clearance

(2014) Kefeng Lu et al.   Autophagy

Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition

(2014) Lei Qiang et al.   Autophagy

Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression

(2014) Zhengzhao Liu et al.   CANCER CELL

Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface

(2014) P Bronsert et al.   JOURNAL OF PATHOLOGY

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

(2014) Vladimir Rogov et al.   MOLECULAR CELL

Histone post-translational modifications regulate autophagy flux and outcome

(2013) Jens Füllgrabe et al.   Autophagy

Autophagy-Mediated Tumor Promotion

(2013) Jessie Yanxiang Guo et al.   CELL

A SUMOylation-Dependent Pathway Regulates SIRT1 Transcription and Lung Cancer Metastasis

(2013) Lina Sun et al.   JNCI-Journal of the National Cancer Institute

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

(2013) Jens Füllgrabe et al.   NATURE

DEDD, a novel tumor repressor, reverses epithelial-mesenchymal transition by activating selective autophagy

(2012) Qi Lv et al.   Autophagy

Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A

(2012) M. Pulvino et al.   BLOOD

DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial-Mesenchymal Transition in Human Breast Cancer

(2012) Q. Lv et al.   CANCER RESEARCH

The mechanism of OTUB1-mediated inhibition of ubiquitination

(2012) Reuven Wiener et al.   NATURE

Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo

(2011) Joon-Ho Sheen et al.   CANCER CELL

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Role of autophagy in suppression of inflammation and cancer

(2010) Eileen White et al.   CURRENT OPINION IN CELL BIOLOGY

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Direct activation of protein kinases by unanchored polyubiquitin chains

(2009) Zong-Ping Xia et al.   NATURE