Exosomal miR-9 inhibits angiogenesis by targeting MDK and regulating PDK/AKT pathway in nasopharyngeal carcinoma

The versatile nature of miR-9/9* in human cance

(2018) Katarzyna Nowek et al.   Oncotarget

MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis

(2017) Romain Madelaine et al.   Cell Reports

The biology and function of exosomes in cancer

(2016) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression

(2016) Jinheng Wang et al.   JOURNAL OF PATHOLOGY

Nasopharyngeal carcinoma

(2016) Melvin L K Chua et al.   LANCET

Exosomal Annexin II Promotes Angiogenesis and Breast Cancer Metastasis

(2016) Sayantan Maji et al.   MOLECULAR CANCER RESEARCH

MDK Protein Overexpression Correlates with the Malignant Status and Prognosis of Non-small Cell Lung Cancer

(2015) Kehua Yuan et al.   ARCHIVES OF MEDICAL RESEARCH

Strong immunoexpression of midkine is associated with multiple lymph node metastases in BRAFV600E papillary thyroid carcinoma

(2015) Yong Won Choi et al.   HUMAN PATHOLOGY

MicroRNA-9 regulates osteoblast differentiation and angiogenesis via the AMPK signaling pathway

(2015) Jining Qu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Transcriptional factor specificity protein 1 (SP1) promotes the proliferation of glioma cells by up-regulating midkine (MDK)

(2015) Jingyan Luo et al.   MOLECULAR BIOLOGY OF THE CELL

Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1

(2014) T. Umezu et al.   BLOOD

Measuring midkine: the utility of midkine as a biomarker in cancer and other diseases

(2014) D R Jones   BRITISH JOURNAL OF PHARMACOLOGY

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Extracellular vesicles: emerging targets for cancer therapy

(2014) Pieter Vader et al.   TRENDS IN MOLECULAR MEDICINE

Predictive value of miR-9 as a potential biomarker for nasopharyngeal carcinoma metastasis

(2013) J Lu et al.   BRITISH JOURNAL OF CANCER

miR-9 targets CXCR4 and functions as a potential tumor suppressor in nasopharyngeal carcinoma

(2013) Juan Lu et al.   CARCINOGENESIS

Dll4 and PDGF-BB Convert Committed Skeletal Myoblasts to Pericytes without Erasing Their Myogenic Memory

(2013) Ornella Cappellari et al.   DEVELOPMENTAL CELL

Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells

(2013) Hiroko Tadokoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

(2013) Aldo M. Roccaro et al.   JOURNAL OF CLINICAL INVESTIGATION

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

(2013) Jonathan Welti et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

(2012) Guanglei Zhuang et al.   EMBO JOURNAL

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Leukemia cell to endothelial cell communication via exosomal miRNAs

(2012) T Umezu et al.   ONCOGENE

Midkine confers Adriamycin resistance in human gastric cancer cells

(2012) Ying-ying Xu et al.   TUMOR BIOLOGY

Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion

(2011) Marco Mineo et al.   ANGIOGENESIS

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

Midkine positively regulates the proliferation of human gastric cancer cells

(2009) Yingying Xu et al.   CANCER LETTERS

Midkine in plasma as a novel breast cancer marker

(2009) Mutsuko Ibusuki et al.   CANCER SCIENCE

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY