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Title
Fate of Antibody-Drug Conjugates in Cancer Cells
Authors
Keywords
Antibody-drug conjugates, Endocytosis, Endocytic compartments, Intracellular trafficking
Journal
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 37, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-06
DOI
10.1186/s13046-017-0667-1
References
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- (2017) Alain Beck et al. NATURE REVIEWS DRUG DISCOVERY
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- (2016) Bertrand Coiffier et al. BRITISH JOURNAL OF HAEMATOLOGY
- A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
- (2016) John Y. Li et al. CANCER CELL
- Mechanisms of Resistance to Antibody–Drug Conjugates
- (2016) Frank Loganzo et al. MOLECULAR CANCER THERAPEUTICS
- Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?
- (2015) L. Apetoh et al. ANNALS OF ONCOLOGY
- Targeting the lysosome in cancer
- (2015) Shengfu Piao et al. Annals of the New York Academy of Sciences
- Antibody-drug conjugates as novel anti-cancer chemotherapeutics
- (2015) C. Peters et al. BIOSCIENCE REPORTS
- SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm
- (2015) K. J. Hamblett et al. CANCER RESEARCH
- A Novel Anti-CD22 Anthracycline-Based Antibody-Drug Conjugate (ADC) That Overcomes Resistance to Auristatin-Based ADCs
- (2015) S.-F. Yu et al. CLINICAL CANCER RESEARCH
- Autophagy, Metabolism, and Cancer
- (2015) E. White et al. CLINICAL CANCER RESEARCH
- Role of autophagy in the maintenance and function of cancer stem cells
- (2015) Ilio Vitale et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- Role of tumor cell surface lysosome-associated membrane protein-1 (LAMP1) and its associated carbohydrates in lung metastasis
- (2015) Akhil Kumar Agarwal et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Tumor Cells Chronically Treated with a Trastuzumab-Maytansinoid Antibody-Drug Conjugate Develop Varied Resistance Mechanisms but Respond to Alternate Treatments
- (2015) F. Loganzo et al. MOLECULAR CANCER THERAPEUTICS
- Novel antibody–antibiotic conjugate eliminates intracellular S. aureus
- (2015) Sophie M. Lehar et al. NATURE
- CD30-targeting immunoconjugates and bystander effects
- (2015) Shigeo Masuda et al. Nature Reviews Clinical Oncology
- A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo
- (2015) Laura R. Saunders et al. Science Translational Medicine
- Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)*
- (2015) David M. Goldenberg et al. Oncotarget
- Antibody–drug conjugates—A new wave of cancer drugs
- (2014) Hervé Bouchard et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Trastuzumab emtansine: mechanisms of action and drug resistance
- (2014) Mark Barok et al. BREAST CANCER RESEARCH
- Exposure–Response Relationship of T-DM1: Insight Into Dose Optimization for Patients With HER2-Positive Metastatic Breast Cancer
- (2014) J Wang et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Overexpression of transferrin receptor CD71 and its tumorigenic properties in esophageal squamous cell carcinoma
- (2014) KIN TAK CHAN et al. ONCOLOGY REPORTS
- Targeting of preexisting and induced breast cancer stem cells with trastuzumab and trastuzumab emtansine (T-DM1)
- (2014) J Diessner et al. Cell Death & Disease
- A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology
- (2013) Scott C. Jeffrey et al. BIOCONJUGATE CHEMISTRY
- Gemtuzumab ozogamicin in acute myeloid leukemia: a remarkable saga about an active drug
- (2013) J. M. Rowe et al. BLOOD
- SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
- (2013) M. S. Kung Sutherland et al. BLOOD
- Dual Targeting of HER2-Positive Cancer with Trastuzumab Emtansine and Pertuzumab: Critical Role for Neuregulin Blockade in Antitumor Response to Combination Therapy
- (2013) G. D. L. Phillips et al. CLINICAL CANCER RESEARCH
- Implications of receptor-mediated endocytosis and intracellular trafficking dynamics in the development of antibody drug conjugates
- (2013) Michael Ritchie et al. mAbs
- Antibody Therapeutics in Cancer
- (2013) M. X. Sliwkowski et al. SCIENCE
- Endocytosis and Cancer
- (2013) I. Mellman et al. Cold Spring Harbor Perspectives in Biology
- Mechanism of action of therapeutic monoclonal antibodies: Promises and pitfalls of in vitro and in vivo assays
- (2012) Josée Golay et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Acute myeloid leukemia stem cells and CD33-targeted immunotherapy
- (2012) R. B. Walter et al. BLOOD
- Antibody-Drug Conjugates for the Treatment of Cancer
- (2012) John A. Flygare et al. Chemical Biology & Drug Design
- The Effect of Different Linkers on Target Cell Catabolism and Pharmacokinetics/Pharmacodynamics of Trastuzumab Maytansinoid Conjugates
- (2012) H. K. Erickson et al. MOLECULAR CANCER THERAPEUTICS
- Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
- (2012) Ben-Quan Shen et al. NATURE BIOTECHNOLOGY
- Dynamin, a membrane-remodelling GTPase
- (2012) Shawn M. Ferguson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer
- (2012) Sunil Verma et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer-associated lysosomal changes: friends or foes?
- (2012) T Kallunki et al. ONCOGENE
- Endocytosis and Signaling: Cell Logistics Shape the Eukaryotic Cell Plan
- (2012) Sara Sigismund et al. PHYSIOLOGICAL REVIEWS
- Trastuzumab Emtansine (T-DM1): A Novel Agent for Targeting HER2+ Breast Cancer
- (2011) Howard A. Burris et al. Clinical Breast Cancer
- Antibody Conjugate Therapeutics: Challenges and Potential
- (2011) B. A. Teicher et al. CLINICAL CANCER RESEARCH
- Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
- (2011) R. K. Amaravadi et al. CLINICAL CANCER RESEARCH
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- (2010) N. M. Okeley et al. CLINICAL CANCER RESEARCH
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- (2010) E. Oroudjev et al. MOLECULAR CANCER THERAPEUTICS
- The endocytic matrix
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- Antibody–drug conjugates for cancer: poised to deliver?
- (2010) Bethan Hughes NATURE REVIEWS DRUG DISCOVERY
- Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling
- (2010) J. B. Spangler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of Endocytosis
- (2009) Gary J. Doherty et al. Annual Review of Biochemistry
- Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas
- (2009) H.-P. Gerber et al. BLOOD
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- (2009) Mario Mairhofer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rab GTPases as coordinators of vesicle traffic
- (2009) Harald Stenmark NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Molecular biology of Hodgkin lymphoma
- (2009) R. Kuppers Hematology-American Society of Hematology Education Program
- Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody-Cytotoxic Drug Conjugate
- (2008) G. D. Lewis Phillips et al. CANCER RESEARCH
- Targeted Cancer Therapy: Conferring Specificity to Cytotoxic Drugs
- (2007) Ravi V. J. Chari ACCOUNTS OF CHEMICAL RESEARCH
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