A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo

Predictors of Survival After Operation Among Patients With Large Cell Neuroendocrine Carcinoma of the Lung

(2015) Florian Eichhorn et al.   ANNALS OF THORACIC SURGERY

Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure

(2015) R. Pagliarini et al.   EMBO REPORTS

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

(2015) J T Poirier et al.   ONCOGENE

Initiation and Characterization of Small Cell Lung Cancer Patient-Derived Xenografts from Ultrasound-Guided Transbronchial Needle Aspirates

(2015) Wade C. Anderson et al.   PLoS One

O-Fucosylation of DLL3 Is Required for Its Function during Somitogenesis

(2015) Katrin Serth et al.   PLoS One

Advances in patient-derived tumor xenografts: From target identification to predicting clinical response rates in oncology

(2014) Edward Rosfjord et al.   BIOCHEMICAL PHARMACOLOGY

Antibody–drug conjugates—A new wave of cancer drugs

(2014) Hervé Bouchard et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling

(2014) Panagiotis Ntziachristos et al.   CANCER CELL

Randomized Phase III Trial of Amrubicin Versus Topotecan As Second-Line Treatment for Patients With Small-Cell Lung Cancer

(2014) Joachim von Pawel et al.   JOURNAL OF CLINICAL ONCOLOGY

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

(2014) A. Augustyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathology and Diagnosis of Neuroendocrine Tumors

(2014) William D. Travis   Thoracic Surgery Clinics

Selective Tropism of Seneca Valley Virus for Variant Subtype Small Cell Lung Cancer

(2013) J. T. Poirier et al.   JNCI-Journal of the National Cancer Institute

Patient-derived xenografts, the cancer stem cell paradigm and cancer pathobiology in the 21st century

(2013) Samuel A Williams et al.   LABORATORY INVESTIGATION

ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation

(2013) F Kosari et al.   ONCOGENE

Notch inhibitors for cancer treatment

(2013) Ingrid Espinoza et al.   PHARMACOLOGY & THERAPEUTICS

A Genomics-Based Classification of Human Lung Tumors

(2013)   Science Translational Medicine

Multidirectional Differentiation of Achaete–Scute Homologue–1–Defined Progenitors in Lung Development and Injury Repair

(2012) Yan Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

(2012) M. Morimoto et al.   DEVELOPMENT

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

(2012) Charles M Rudin et al.   NATURE GENETICS

Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis

(2012) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protease-Activated Drug Development

(2012) Ki Young Choi et al.   Theranostics

Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

(2011) Kate D. Sutherland et al.   CANCER CELL

Characterization of the cell of origin for small cell lung cancer

(2011) Kwon-Sik Park et al.   CELL CYCLE

Phase I Pharmacokinetic and Pharmacodynamic Study of SJG-136, a Novel DNA Sequence Selective Minor Groove Cross-linking Agent, in Advanced Solid Tumors

(2011) I. Puzanov et al.   CLINICAL CANCER RESEARCH

Novel strategies for the treatment of small-cell lung carcinoma

(2011) William N. William et al.   Nature Reviews Clinical Oncology

Advances in neuroendocrine lung tumors

(2010) W. D. Travis   ANNALS OF ONCOLOGY

Notch inhibition by the ligand Delta-Like 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis

(2010) Gavin Chapman et al.   HUMAN MOLECULAR GENETICS

Achaete-Scute Complex Homologue 1 Regulates Tumor-Initiating Capacity in Human Small Cell Lung Cancer

(2009) T. Jiang et al.   CANCER RESEARCH

Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube

(2009) R. Michael Henke et al.   DEVELOPMENTAL BIOLOGY

Stomatin-like Protein-1 Interacts with Stomatin and Is Targeted to Late Endosomes

(2009) Mario Mairhofer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY