Efficient use of single molecule time traces to resolve kinetic rates, models and uncertainties

Single-Molecule Analysis beyond Dwell Times: Demonstration and Assessment in and out of Equilibrium

(2016) Sonja Schmid et al.   BIOPHYSICAL JOURNAL

Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism

(2016) Andrea Schulze et al.   Nature Chemical Biology

Multidomain structure and correlated dynamics determined by self-consistent FRET networks

(2016) Björn Hellenkamp et al.   NATURE METHODS

Real-time single-molecule studies of the motions of DNA polymerase fingers illuminate DNA synthesis mechanisms

(2015) Geraint W. Evans et al.   NUCLEIC ACIDS RESEARCH

The role of monovalent cations in the ATPase reaction of DNA gyrase

(2015) Stephen James Hearnshaw et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Dynamic Architecture of a Minimal RNA Polymerase II Open Promoter Complex

(2012) Barbara Treutlein et al.   MOLECULAR CELL

A New Method for Inferring Hidden Markov Models from Noisy Time Sequences

(2012) David Kelly et al.   PLoS One

Single Molecule Analysis Research Tool (SMART): An Integrated Approach for Analyzing Single Molecule Data

(2012) Max Greenfeld et al.   PLoS One

The ‘active life’ of Hsp90 complexes

(2011) Chrisostomos Prodromou   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Photon budget analysis for fluorescence lifetime imaging microscopy

(2011) Qiaole Zhao et al.   JOURNAL OF BIOMEDICAL OPTICS

Communications: Can one identify nonequilibrium in a three-state system by analyzing two-state trajectories?

(2010) Christian P. Amann et al.   JOURNAL OF CHEMICAL PHYSICS

A Comparative Study of Multivariate and Univariate Hidden Markov Modelings in Time-Binned Single-Molecule FRET Data Analysis

(2010) Yang Liu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

(2009) Moritz Mickler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational transitions in DNA polymerase I revealed by single-molecule FRET

(2009) Y. Santoso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flexibility and enzyme activity of NADH oxidase from Thermus thermophilus in the presence of monovalent cations of Hofmeister series

(2008) Kamil Tóth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Conserved Conformational Changes in the ATPase Cycle of Human Hsp90

(2008) Klaus Richter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY