Multidomain structure and correlated dynamics determined by self-consistent FRET networks

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

Direct observation of structure-function relationship in a nucleic acid-processing enzyme

(2015) M. J. Comstock et al.   SCIENCE

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

(2014) Mikko Taipale et al.   CELL

The charged linker of the molecular chaperone Hsp90 modulates domain contacts and biological function

(2014) Markus Jahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperone Action at the Single-Molecule Level

(2013) Alireza Mashaghi et al.   CHEMICAL REVIEWS

HSP90 Inhibitors: Current Development and Potential in Cancer Therapy

(2013) Katerina Sidera et al.   Recent Patents on Anti-Cancer Drug Discovery

Cryptic Variation in Morphological Evolution: HSP90 as a Capacitor for Loss of Eyes in Cavefish

(2013) N. Rohner et al.   SCIENCE

Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion

(2013) Johannes Hohlbein et al.   Nature Communications

Single-molecule FRET of protein structure and dynamics - a primer

(2013) Benjamin Schuler   JOURNAL OF NANOBIOTECHNOLOGY

Combining MFD and PIE for Accurate Single-Pair Förster Resonance Energy Transfer Measurements

(2012) Volodymyr Kudryavtsev et al.   CHEMPHYSCHEM

Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?

(2012) L. Neckers et al.   CLINICAL CANCER RESEARCH

A toolkit and benchmark study for FRET-restrained high-precision structural modeling

(2012) Stanislav Kalinin et al.   NATURE METHODS

Conformational dynamics of the molecular chaperone Hsp90

(2011) Kristin A. Krukenberg et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy

(2010) James R Porter et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Three-dimensional molecular modeling with single molecule FRET

(2010) Axel T. Brunger et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural Basis of the Radicicol Resistance Displayed by a Fungal Hsp90

(2009) Chrisostomos Prodromou et al.   ACS Chemical Biology

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

(2009) Moritz Mickler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A nano-positioning system for macromolecular structural analysis

(2008) Adam Muschielok et al.   NATURE METHODS

Multiple Conformations of E. coli Hsp90 in Solution: Insights into the Conformational Dynamics of Hsp90

(2008) Kristin A. Krukenberg et al.   STRUCTURE