SB-216763, a GSK-3β inhibitor, protects against aldosterone-induced cardiac, and renal injury by activating autophagy

GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration

(2017) Shuji Wakatsuki et al.   JOURNAL OF CELL BIOLOGY

1,25-Dihydroxyvitamin-D3 prevents the development of diabetic cardiomyopathy in type 1 diabetic rats by enhancing autophagy via inhibiting the β-catenin/TCF4/GSK-3β/mTOR pathway

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Recycling to discover something new: the role of autophagy in kidney disease

(2017) Jeremy S. Leventhal et al.   KIDNEY INTERNATIONAL

Autophagy in kidney disease and aging: lessons from rodent models

(2016) Olivia Lenoir et al.   KIDNEY INTERNATIONAL

Too much or not enough of a good thing — The Janus faces of autophagy in cardiac fuel and protein homeostasis

(2015) Jun Ren et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IFN-  Production by TLR4-Stimulated Innate Immune Cells Is Negatively Regulated by GSK3- 

(2014) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Inflammatory processes in renal fibrosis

(2014) Xiao-Ming Meng et al.   Nature Reviews Nephrology

Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth

(2014) I Azoulay-Alfaguter et al.   ONCOGENE

Mizoribine Ameliorates Renal Injury and Hypertension along with the Attenuation of Renal Caspase-1 Expression in Aldosterone-Salt-Treated Rats

(2014) Toshiki Doi et al.   PLoS One

The role of renal damage on cardiac remodeling in patients with diabetic nephropathy

(2013) Yi-De Zhang et al.   CLINICAL NEPHROLOGY

Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia

(2013) Linli Yao et al.   Journal of Neuroinflammation

Contribution of aldosterone to cardiovascular and renal inflammation and fibrosis

(2013) Nancy J. Brown   Nature Reviews Nephrology

GSK-3β inhibitors suppressed neuroinflammation in rat cortex by activating autophagy in ischemic brain injury

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Differential Roles of GSK-3β During Myocardial Ischemia and Ischemia/Reperfusion

(2011) Peiyong Zhai et al.   CIRCULATION RESEARCH

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Constitutive glycogen synthase kinase-3α/β activity protects against chronic β-adrenergic remodelling of the heart

(2010) Ian G. Webb et al.   CARDIOVASCULAR RESEARCH

Viruses and the autophagy machinery

(2010) Marlène Dreux et al.   CELL CYCLE

Using Small Molecule GSK3β Inhibitors to Treat Inflammation

(2010) G. Klamer et al.   CURRENT MEDICINAL CHEMISTRY

Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes

(2010) Shubham Shrivastava et al.   HEPATOLOGY

miR-29 Modulates Wnt Signaling in Human Osteoblasts through a Positive Feedback Loop

(2010) Kristina Kapinas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GSK-3β promotes cell survival by modulating Bif-1-dependent autophagy and cell death

(2010) Jun Yang et al.   JOURNAL OF CELL SCIENCE

Pathophysiological Roles of Aldosterone and Mineralocorticoid Receptor in the Kidney

(2010) Kazi Rafiq et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Mechanistic connection between inflammation and fibrosis

(2010) Soo Bong Lee et al.   KIDNEY INTERNATIONAL

Aldosterone: effects on the kidney and cardiovascular system

(2010) Marie Briet et al.   Nature Reviews Nephrology

Combination of Imipenem and TAK-242, a Toll-Like Receptor 4 Signal Transduction Inhibitor, Improves Survival in a Murine Model of Polymicrobial Sepsis

(2010) Takukyu Sha et al.   SHOCK

Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia

(2010) Q Li et al.   Cell Death & Disease

Glycogen synthase kinase 3: more than a namesake

(2009) Geetha Vani Rayasam et al.   BRITISH JOURNAL OF PHARMACOLOGY

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Autophagy genes in immunity

(2009) Herbert W Virgin et al.   NATURE IMMUNOLOGY

Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3β in Mesangial Cells

(2009) Sheng-Hao Wang et al.   TOXICOLOGICAL SCIENCES

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)

(2009) Eléonore Beurel et al.   TRENDS IN IMMUNOLOGY

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE