The Joubert syndrome protein ARL13B binds tubulin to maintain uniform distribution of proteins along the ciliary membrane

Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF)

(2017) Anna A. Ivanova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultra-High Resolution 3D Imaging of Whole Cells

(2016) Fang Huang et al.   CELL

Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway

(2016) Laura Grisanti et al.   DEVELOPMENT

Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E

(2016) Shohei Nozaki et al.   JOURNAL OF CELL SCIENCE

Arl13b regulates Shh signaling from both inside and outside the cilium

(2016) Laura E. Mariani et al.   MOLECULAR BIOLOGY OF THE CELL

GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119

(2016) Qing Zhang et al.   Scientific Reports

IFT–Cargo Interactions and Protein Transport in Cilia

(2015) Karl F. Lechtreck   TRENDS IN BIOCHEMICAL SCIENCES

A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

(2015) Katja Gotthardt et al.   eLife

Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity

(2014) Sophie Thomas et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Arl13b and the non-muscle myosin heavy chain IIA are required for circular dorsal ruffle formation and cell migration

(2014) C. Casalou et al.   JOURNAL OF CELL SCIENCE

Structural insights into the small G-protein Arl13B and implications for Joubert syndrome

(2013) Mandy Miertzschke et al.   BIOCHEMICAL JOURNAL

Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity

(2013) Y. Zhang et al.   DEVELOPMENT

The roles of evolutionarily conserved functional modules in cilia-related trafficking

(2013) Ching-Hwa Sung et al.   NATURE CELL BIOLOGY

Active Transport and Diffusion Barriers Restrict Joubert Syndrome-Associated ARL13B/ARL-13 to an Inv-like Ciliary Membrane Subdomain

(2013) Sebiha Cevik et al.   PLoS Genetics

A role for the vesicle-associated tubulin binding protein ARL6 (BBS3) in flagellum extension in Trypanosoma brucei

(2012) Helen P. Price et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Defective Nodal and Cerl2 expression in the Arl13bhnn mutant node underlie its heterotaxia

(2012) Christine E. Larkins et al.   DEVELOPMENTAL BIOLOGY

A Smoothened-Evc2 Complex Transduces the Hedgehog Signal at Primary Cilia

(2012) Karolin V. Dorn et al.   DEVELOPMENTAL CELL

Arl13b regulates endocytic recycling traffic

(2012) D. C. Barral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

(2012) M. C. Humbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins

(2011) Christine E. Larkins et al.   MOLECULAR BIOLOGY OF THE CELL

A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1

(2011) Heather H. Ward et al.   MOLECULAR BIOLOGY OF THE CELL

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

(2011) Beate Schwer et al.   NUCLEIC ACIDS RESEARCH

Trafficking to the Ciliary Membrane: How to Get Across the Periciliary Diffusion Barrier?

(2010) Maxence V. Nachury et al.   Annual Review of Cell and Developmental Biology

The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia

(2010) Hua Jin et al.   CELL

Development of head organizer of the mouse embryo depends on a high level of mitochondrial metabolism

(2010) Xin Zhou et al.   DEVELOPMENTAL BIOLOGY

TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

(2010) S. Mukhopadhyay et al.   GENES & DEVELOPMENT

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport inCaenorhabditis elegans

(2010) Sebiha Cevik et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanisms of protein and lipid targeting to ciliary membranes

(2010) B. T. Emmer et al.   JOURNAL OF CELL SCIENCE

Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex

(2010) S. Miserey-Lenkei et al.   NATURE CELL BIOLOGY

ADP-ribosylation factor like 7 (ARL7) interacts with α-tubulin and modulates intracellular vesicular transport

(2009) Shu-mei Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chlamydomonas CAV2 Encodes a Voltage- Dependent Calcium Channel Required for the Flagellar Waveform Conversion

(2009) Kenta Fujiu et al.   CURRENT BIOLOGY

Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion

(2009) N. A. Duldulao et al.   DEVELOPMENT

High-throughput generation of tagged stable cell lines for proteomic analysis

(2009) Jorge Z. Torres et al.   PROTEOMICS

Mutations in the Cilia Gene ARL13B Lead to the Classical Form of Joubert Syndrome

(2008) Vincent Cantagrel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation

(2008) Yuji Hori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of polycystin-1 causes centrosome amplification and genomic instability

(2008) Lorenzo Battini et al.   HUMAN MOLECULAR GENETICS

Topology of Amphipathic Motifs Mediating Golgi Localization in ArfGAP1 and Its Splice Isoforms

(2008) Sharon Levi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY