The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1

An Emerging Group of Membrane Property Sensors Controls the Physical State of Organellar Membranes to Maintain Their Identity

(2018) Toni Radanović et al.   BIOESSAYS

Cellular mechanisms of physicochemical membrane homeostasis

(2018) Robert Ernst et al.   CURRENT OPINION IN CELL BIOLOGY

Comparative Characterization of Phosphatidic Acid Sensors and Their Localization during Frustrated Phagocytosis

(2017) Nawal Kassas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction between repressor Opi1p and ER membrane protein Scs2p facilitates transit of phosphatidic acid from the ER to mitochondria and is essential forINO1gene expression in the presence of choline

(2017) Maria L. Gaspar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Unfolded Protein Response by Lipid Bilayer Stress

(2017) Kristina Halbleib et al.   MOLECULAR CELL

Phosphatidic acid binding proteins display differential binding as a function of membrane curvature stress and chemical properties

(2016) Priya Putta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Endoplasmic reticulum stress in beta cells and autoimmune diabetes

(2016) Amy L Clark et al.   CURRENT OPINION IN IMMUNOLOGY

Lipid droplet–mediated ER homeostasis regulates autophagy and cell survival during starvation

(2016) Ariadna P. Velázquez et al.   JOURNAL OF CELL BIOLOGY

A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis

(2016) Lin Jin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amphipathicity Determines Different Cytotoxic Mechanisms of Lysine- or Arginine-Rich Cationic Hydrophobic Peptides in Cancer Cells

(2016) Xiaoli Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Homeoviscous Adaptation and the Regulation of Membrane Lipids

(2016) Robert Ernst et al.   JOURNAL OF MOLECULAR BIOLOGY

A Eukaryotic Sensor for Membrane Lipid Saturation

(2016) Roberto Covino et al.   MOLECULAR CELL

Energetics of side-chain snorkeling in transmembrane helices probed by nonproteinogenic amino acids

(2016) Karin Öjemalm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition

(2016) Maud Magdeleine et al.   eLife

Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast

(2015) Heimo Wolinski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Homeostatic control of biological membranes by dedicated lipid and membrane packing sensors

(2015) Kristina Puth et al.   BIOLOGICAL CHEMISTRY

The seipin complex Fld1/Ldb16 stabilizes ER–lipid droplet contact sites

(2015) Alexandra Grippa et al.   JOURNAL OF CELL BIOLOGY

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

From zero to six double bonds: phospholipid unsaturation and organelle function

(2015) Bruno Antonny et al.   TRENDS IN CELL BIOLOGY

Regulation of Gene Expression through a Transcriptional Repressor that Senses Acyl-Chain Length in Membrane Phospholipids

(2014) Harald F. Hofbauer et al.   DEVELOPMENTAL CELL

Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

(2014) Robert B. Best et al.   Journal of Chemical Theory and Computation

Lipid landscapes and pipelines in membrane homeostasis

(2014) Joost C.M. Holthuis et al.   NATURE

Interaction of the Spo20 Membrane-Sensor Motif with Phosphatidic Acid and Other Anionic Lipids, and Influence of the Membrane Environment

(2014) Habib Horchani et al.   PLoS One

Membrane lipid saturation activates IRE1α without inducing clustering

(2013) Yuto Kitai et al.   GENES TO CELLS

Going Backward: A Flexible Geometric Approach to Reverse Transformation from Coarse Grained to Atomistic Models

(2013) Tsjerk A. Wassenaar et al.   Journal of Chemical Theory and Computation

The Different Interactions of Lysine and Arginine Side Chains with Lipid Membranes

(2013) Libo Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Temporal Production of the Signaling Lipid Phosphatidic Acid by Phospholipase D2 Determines the Output of Extracellular Signal-Regulated Kinase Signaling in Cancer Cells

(2013) F. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

A Lipid E-MAP Identifies Ubx2 as a Critical Regulator of Lipid Saturation and Lipid Bilayer Stress

(2013) Michal A. Surma et al.   MOLECULAR CELL

Checks and balances in membrane phospholipid class and acyl chain homeostasis, the yeast perspective

(2013) Anton I.P.M. de Kroon et al.   PROGRESS IN LIPID RESEARCH

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Curvature, Lipid Packing, and Electrostatics of Membrane Organelles: Defining Cellular Territories in Determining Specificity

(2012) Joëlle Bigay et al.   DEVELOPMENTAL CELL

Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae

(2012) Susan A. Henry et al.   GENETICS

Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane

(2012) Mathias J. Gerl et al.   JOURNAL OF CELL BIOLOGY

Improved Parameters for the Martini Coarse-Grained Protein Force Field

(2012) Djurre H. de Jong et al.   Journal of Chemical Theory and Computation

Flexibility of a Eukaryotic Lipidome – Insights from Yeast Lipidomics

(2012) Christian Klose et al.   PLoS One

Mechanisms of Membrane Curvature Sensing

(2011) Bruno Antonny   Annual Review of Biochemistry

The NumPy Array: A Structure for Efficient Numerical Computation

(2011) Stéfan van der Walt et al.   COMPUTING IN SCIENCE & ENGINEERING

Molecular Convergence of Bacterial and Eukaryotic Surface Order

(2011) Hermann-Josef Kaiser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MDAnalysis: A toolkit for the analysis of molecular dynamics simulations

(2011) Naveen Michaud-Agrawal et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Molecular, cellular, and physiological responses to phosphatidic acid formation in plants

(2011) C. Testerink et al.   JOURNAL OF EXPERIMENTAL BOTANY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Cationic Amphiphiles, a New Generation of Antimicrobials Inspired by the Natural Antimicrobial Peptide Scaffold

(2010) B. Findlay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Coordination of Storage Lipid Synthesis and Membrane Biogenesis

(2010) Maria L. Gaspar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A phosphorylation-regulated amphipathic helix controls the membrane translocation and function of the yeast phosphatidate phosphatase

(2010) Eleftherios Karanasios et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism

(2010) B. P. Young et al.   SCIENCE

Modulation of Lipid-Induced ER Stress by Fatty Acid Shape

(2010) Julie Deguil et al.   TRAFFIC

Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells

(2009) David A. Foster   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes

(2009) Sunhwan Jo et al.   BIOPHYSICAL JOURNAL

Amphipathic helices and membrane curvature

(2009) Guillaume Drin et al.   FEBS LETTERS

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

(2009) Sebastian Schuck et al.   JOURNAL OF CELL BIOLOGY

Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

(2009) Robin W. Klemm et al.   JOURNAL OF CELL BIOLOGY

CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields

(2009) K. Vanommeslaeghe et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-Induced ER Stress: Synergistic Effects of Sterols and Saturated Fatty Acids

(2009) Ludovic Pineau et al.   TRAFFIC

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Coarse Master Equations for Peptide Folding Dynamics†

(2008) Nicolae-Viorel Buchete et al.   JOURNAL OF PHYSICAL CHEMISTRY B