Temporal Production of the Signaling Lipid Phosphatidic Acid by Phospholipase D2 Determines the Output of Extracellular Signal-Regulated Kinase Signaling in Cancer Cells

Novel Model for Basaloid Triple-negative Breast Cancer: Behavior In Vivo and Response to Therapy

(2015) Lisa D Volk-Draper et al.   NEOPLASIA

Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes

(2013) Michal Bohdanowicz et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization

(2012) Akua N. Roach et al.   JOURNAL OF LIPID RESEARCH

Mammalian phospholipase D physiological and pathological roles

(2011) X. Peng et al.   Acta Physiologica

Regulation of Phospholipid Synthesis in the YeastSaccharomyces cerevisiae

(2011) George M. Carman et al.   Annual Review of Biochemistry

Regulation and Functions of Diacylglycerol Kinases

(2011) Yulia V. Shulga et al.   CHEMICAL REVIEWS

Phospholipase D: Enzymology, Functionality, and Chemical Modulation

(2011) Paige E. Selvy et al.   CHEMICAL REVIEWS

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Ras trafficking, localization and compartmentalized signalling

(2011) Ian A. Prior et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

Heterogeneity of Phosphatidic Acid Levels and Distribution at the Plasma Membrane in Living Cells as Visualized by a Förster Resonance Energy Transfer (FRET) Biosensor

(2010) Teruko Nishioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase D2 Ablation Ameliorates Alzheimer's Disease-Linked Synaptic Dysfunction and Cognitive Deficits

(2010) T. G. Oliveira et al.   JOURNAL OF NEUROSCIENCE

Compartmentalized Ras Proteins Transform NIH 3T3 Cells with Different Efficiencies

(2010) C.-M. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Epidermal Growth Factor Receptor Activation Remodels the Plasma Membrane Lipid Environment To Induce Nanocluster Formation

(2010) N. Ariotti et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphatidic acid signaling regulation of Ras superfamily of small guanosine triphosphatases

(2009) Yueqiang Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells

(2009) David A. Foster   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Inter-regulatory dynamics of phospholipase D and the actin cytoskeleton

(2009) Simon A. Rudge et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipidomics: a mass spectrometry based systems level analysis of cellular lipids

(2009) Pavlina T Ivanova et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Phospholipase D1 Regulates Lymphocyte Adhesion via Upregulation of Rap1 at the Plasma Membrane

(2009) A. Mor et al.   MOLECULAR AND CELLULAR BIOLOGY

Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

(2009) Sarah A Scott et al.   Nature Chemical Biology

Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis

(2009) A. Nishikimi et al.   SCIENCE

Role of Phosphatidic Acid in the Coupling of the ERK Cascade

(2008) Catherine A. Kraft et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Lipid-signaled Myosin Phosphatase Surge Disperses Cortical Contractile Force Early in Cell Spreading

(2008) Guangwei Du et al.   MOLECULAR BIOLOGY OF THE CELL

5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a Phospholipase D Pharmacological Inhibitor That Alters Cell Spreading and Inhibits Chemotaxis

(2008) W. Su et al.   MOLECULAR PHARMACOLOGY

Using plasma membrane nanoclusters to build better signaling circuits

(2008) Angus S. Harding et al.   TRENDS IN CELL BIOLOGY