β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells

Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel

(2017) Anindit Mukherjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NEDD4-2 (NEDD4L): The ubiquitin ligase for multiple membrane proteins

(2015) Pranay Goel et al.   GENE

mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity

(2014) Catherine E. Gleason et al.   JOURNAL OF CLINICAL INVESTIGATION

Evaluating Strategies to Normalise Biological Replicates of Western Blot Data

(2014) Andrea Degasperi et al.   PLoS One

Cool-1-Mediated Inhibition of c-Cbl Modulates Multiple Critical Properties of Glioblastomas, Including the Ability to Generate Tumors In Vivo

(2014) Brett M. Stevens et al.   STEM CELLS

A βPIX-PAK2 Complex Confers Protection against Scrib-Dependent and Cadherin-Mediated Apoptosis

(2012) Scott R. Frank et al.   CURRENT BIOLOGY

AMP-activated protein kinase regulation of kidney tubular transport

(2012) Núria M. Pastor-Soler et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Role of βPix in the Kidney

(2012) Alexander Staruschenko et al.   Frontiers in Physiology

Neural Precursor Cell-expressed Developmentally Down-regulated Protein 4-2 (Nedd4-2) Regulation by 14-3-3 Protein Binding at Canonical Serum and Glucocorticoid Kinase 1 (SGK1) Phosphorylation Sites

(2011) Sindhu Chandran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sorting Nexin 27 Protein Regulates Trafficking of a p21-activated Kinase (PAK) Interacting Exchange Factor (β-Pix)-G Protein-coupled Receptor Kinase Interacting Protein (GIT) Complex via a PDZ Domain Interaction

(2011) Julie L. Valdes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

(2011) V. Takiar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+Channel

(2010) Kenneth R. Hallows et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelin-1 Inhibits the Epithelial Na+ Channel through  Pix/14-3-3/Nedd4-2

(2010) T. S. Pavlov et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tracking and quantification of 32P-labeled phosphopeptides in liquid chromatography matrix-assisted laser desorption/ionization mass spectrometry

(2009) Roland D. Tuerk et al.   ANALYTICAL BIOCHEMISTRY

Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells

(2009) A. Peairs et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis

(2009) Nabil Djouder et al.   EMBO JOURNAL

AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated

(2009) Joana Almaça et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Regulation of ENaC expression at the cell surface by Rab11

(2008) Alexey V. Karpushev et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional Regulation of the Epithelial Na+Channel by IκB Kinase-β Occurs via Phosphorylation of the Ubiquitin Ligase Nedd4-2

(2008) Robert S. Edinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adiponectin regulates albuminuria and podocyte function in mice

(2008) Kumar Sharma et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of ENaC Regulation and Clinical Implications

(2008) V. Bhalla et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Endothelin-1 Couples βPix to p66Shc: Role of βPix in Cell Proliferation through FOXO3a Phosphorylation and p27kip1 Down-Regulation Independently of Akt

(2008) Ahmed Chahdi et al.   MOLECULAR BIOLOGY OF THE CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

(2008) Deborah K. Morrison   TRENDS IN CELL BIOLOGY