Cool-1-Mediated Inhibition of c-Cbl Modulates Multiple Critical Properties of Glioblastomas, Including the Ability to Generate Tumors In Vivo

In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells

(2014) Prakash Rath et al.   Translational Oncology

Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells

(2013) Hsing-Yu Chen et al.   EMBO Molecular Medicine

c-Cbl, a Ubiquitin E3 Ligase That Targets Active β-Catenin

(2013) Vipul Chitalia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD133 Is Essential for Glioblastoma Stem Cell Maintenance

(2013) Paola Brescia et al.   STEM CELLS

A Mechanism for the Upregulation of EGF Receptor Levels in Glioblastomas

(2013) Jingwen Zhang et al.   Cell Reports

The EphA2 Receptor Drives Self-Renewal and Tumorigenicity in Stem-like Tumor-Propagating Cells from Human Glioblastomas

(2012) Elena Binda et al.   CANCER CELL

The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype

(2012) F. De Bacco et al.   CANCER RESEARCH

MET Signaling Regulates Glioblastoma Stem Cells

(2012) K. M. Joo et al.   CANCER RESEARCH

Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells

(2012) Kang Ho Kim et al.   NEURO-ONCOLOGY

siRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth

(2011) Jianpeng Wang et al.   MOLECULAR BIOLOGY REPORTS

c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype

(2011) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the Cool-1/β-Pix Protein Serves as a Regulatory Signal for the Migration and Invasive Activity of Src-transformed Cells

(2010) Qiyu Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CBL Is Frequently Altered in Lung Cancers: Its Relationship to Mutations in MET and EGFR Tyrosine Kinases

(2010) Yi-Hung Carol Tan et al.   PLoS One

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia

(2009) M. L. Loh et al.   BLOOD

SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma

(2009) Myung Jin Son et al.   Cell Stem Cell

Phase II Trial of Temozolomide Plus O6-Benzylguanine in Adults With Recurrent, Temozolomide-Resistant Malignant Glioma

(2009) Jennifer A. Quinn et al.   JOURNAL OF CLINICAL ONCOLOGY

Trans-sodium crocetinate enhancing survival and glioma response on magnetic resonance imaging to radiation and temozolomide

(2009) Jason Sheehan et al.   JOURNAL OF NEUROSURGERY

Oncogenic EGFR Signaling Networks in Glioma

(2009) P. H. Huang et al.   Science Signaling

SOX2Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity

(2008) Rosaria Maria Rita Gangemi et al.   STEM CELLS