Mycobacterium tuberculosisPPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2–dependent maturation of dendritic cells

NLRP3 inflammasome activation by mycobacterial ESAT-6 and dsRNA in intraocular tuberculosis

(2018) Soumyava Basu et al.   MICROBIAL PATHOGENESIS

Next-Generation Vaccines Based on Bacille Calmette–Guérin

(2018) Natalie E. Nieuwenhuizen et al.   Frontiers in Immunology

Polyfunctional CD4+ T Cells As Targets for Tuberculosis Vaccination

(2017) Deborah A. Lewinsohn et al.   Frontiers in Immunology

Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases

(2017) Bas C. Mourik et al.   Frontiers in Immunology

Toll-like receptor 2 in host defense against Mycobacterium tuberculosis : to be or not to be — that is the question

(2016) Archana Gopalakrishnan et al.   CURRENT OPINION IN IMMUNOLOGY

Giving CD4+ T cells the slip: viral interference with MHC class II-restricted antigen processing and presentation

(2016) Katherine S Forsyth et al.   CURRENT OPINION IN IMMUNOLOGY

Mycobacterium tuberculosis PE27 activates dendritic cells and contributes to Th1-polarized memory immune responses during in vivo infection

(2016) Woo Sik Kim et al.   IMMUNOBIOLOGY

ESAT-6–dependent cytosolic pattern recognition drives noncognate tuberculosis control in vivo

(2016) Andreas Kupz et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

(2016) Fadel Sayes et al.   PLoS Pathogens

Mycobacterium tuberculosis Co-operonic PE32/PPE65 Proteins Alter Host Immune Responses by Hampering Th1 Response

(2016) Mohd Khubaib et al.   Frontiers in Microbiology

Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47

(2016) Neeraj K. Saini et al.   Nature Microbiology

PPE57 induces activation of macrophages and drives Th1-type immune responses through TLR2

(2015) Ying Xu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Phylogeny to function: PE/PPE protein evolution and impact onMycobacterium tuberculosispathogenicity

(2015) S. Fishbein et al.   MOLECULAR MICROBIOLOGY

PPE26 induces TLR2-dependent activation of macrophages and drives Th1-type T-cell immunity by triggering the cross-talk of multiple pathways involved in the host response

(2015) Haibo Su et al.   Oncotarget

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions betweenMycobacterium tuberculosisand Innate Immune Cells

(2015) Jonathan Kevin Sia et al.   Journal of Immunology Research

Analysis of Th1, Th17 and regulatory T cells in tuberculosis case contacts

(2014) R.E. García Jacobo et al.   CELLULAR IMMUNOLOGY

Identification of Human T Cell Antigens for the Development of Vaccines against Mycobacterium tuberculosis

(2014) S. Bertholet et al.   JOURNAL OF IMMUNOLOGY

Unexpected Role for IL-17 in Protective Immunity against Hypervirulent Mycobacterium tuberculosis HN878 Infection

(2014) Radha Gopal et al.   PLoS Pathogens

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome

(2013) T. Fernandes-Alnemri et al.   JOURNAL OF IMMUNOLOGY

The PPE Domain of PPE17 Is Responsible for Its Surface Localization and Can Be Used to Express Heterologous Proteins on the Mycobacterial Surface

(2013) Valentina Donà et al.   PLoS One

Immunogenicity and protective efficacy of novel Mycobacterium tuberculosis antigens

(2013) Steven C. Derrick et al.   VACCINE

Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship

(2013) Volker Briken et al.   Frontiers in Cellular and Infection Microbiology

Strong Immunogenicity and Cross-Reactivity of Mycobacterium tuberculosis ESX-5 Type VII Secretion -Encoded PE-PPE Proteins Predicts Vaccine Potential

(2012) Fadel Sayes et al.   Cell Host & Microbe

Recombinant live vaccine candidates against tuberculosis

(2012) Stefan HE Kaufmann et al.   CURRENT OPINION IN BIOTECHNOLOGY

Conserved Immune Recognition Hierarchy of Mycobacterial PE/PPE Proteins during Infection in Natural Hosts

(2012) H. Martin Vordermeier et al.   PLoS One

The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: Perhaps more?

(2011) Yusuf Akhter et al.   BIOCHIMIE

Mycobacterial PE/PPE Proteins at the Host-Pathogen Interface

(2011) Samantha L. Sampson   Clinical & Developmental Immunology

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

(2011) Anca Dorhoi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway

(2011) Gustavo A. de Souza et al.   Journal of Proteomics

Functional Dissection of the PE Domain Responsible for Translocation of PE_PGRS33 across the Mycobacterial Cell Wall

(2011) Alessandro Cascioferro et al.   PLoS One

The PE and PPE proteins of Mycobacterium tuberculosis

(2011) Sangita Mukhopadhyay et al.   TUBERCULOSIS

Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate

(2011) Hillarie Plessner Windish et al.   VACCINE

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

Src Homology 3-interacting Domain of Rv1917c ofMycobacterium tuberculosisInduces Selective Maturation of Human Dendritic Cells by Regulating PI3K-MAPK-NF-κB Signaling and Drives Th2 Immune Responses

(2010) Kushagra Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection withMycobacterium tuberculosis

(2010) Andrea Cruz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PE_PGRS Antigens of Mycobacterium tuberculosis Induce Maturation and Activation of Human Dendritic Cells

(2010) K. Bansal et al.   JOURNAL OF IMMUNOLOGY

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

(2010) Iñaki Comas et al.   NATURE GENETICS

Portrait of a Pathogen: The Mycobacterium tuberculosis Proteome In Vivo

(2010) Nicole A. Kruh et al.   PLoS One

The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage

(2009) S. Nair et al.   JOURNAL OF IMMUNOLOGY

Intradermal immunization improves protective efficacy of a novel TB vaccine candidate

(2009) Susan L. Baldwin et al.   VACCINE

Distinct chemokine and cytokine gene expression pattern of murine dendritic cells and macrophages in response to Mycobacterium tuberculosis infection

(2008) Sihyug Jang et al.   JOURNAL OF LEUKOCYTE BIOLOGY