Phylogeny to function: PE/PPE protein evolution and impact onMycobacterium tuberculosispathogenicity
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Title
Phylogeny to function: PE/PPE protein evolution and impact onMycobacterium tuberculosispathogenicity
Authors
Keywords
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Journal
MOLECULAR MICROBIOLOGY
Volume 96, Issue 5, Pages 901-916
Publisher
Wiley
Online
2015-02-26
DOI
10.1111/mmi.12981
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Note: Only part of the references are listed.- The PGRS domain is responsible for translocation of PE_PGRS30 to cell poles while the PE and the C-terminal domains localize it to the cell wall
- (2014) Shweta Chatrath et al. FEBS LETTERS
- Structure of theMycobacterium tuberculosistype VII secretion system chaperone EspG5in complex with PE25-PPE41 dimer
- (2014) Natalia Korotkova et al. MOLECULAR MICROBIOLOGY
- Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion
- (2014) D. C. Ekiert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sequence Diversity in the pe_pgrs Genes of Mycobacterium tuberculosis Is Independent of Human T Cell Recognition
- (2014) R. Copin et al. mBio
- The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis
- (2014) Luis Solans et al. PLoS Pathogens
- Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis
- (2014) Keertan Dheda et al. Lancet Respiratory Medicine
- PPE2 protein ofMycobacterium tuberculosismay inhibit nitric oxide in activated macrophages
- (2013) Khalid Hussain Bhat et al. Annals of the New York Academy of Sciences
- The evolutionary pressures that have molded Mycobacterium tuberculosis into an infectious adjuvant
- (2013) David G Russell CURRENT OPINION IN MICROBIOLOGY
- The PPE Domain of PPE17 Is Responsible for Its Surface Localization and Can Be Used to Express Heterologous Proteins on the Mycobacterial Surface
- (2013) Valentina Donà et al. PLoS One
- The PE16 (Rv1430) of Mycobacterium tuberculosis Is an Esterase Belonging to Serine Hydrolase Superfamily of Proteins
- (2013) Rafiya Sultana et al. PLoS One
- Evolution of Smooth Tubercle Bacilli PE and PE_PGRS Genes: Evidence for a Prominent Role of Recombination and Imprint of Positive Selection
- (2013) Amine Namouchi et al. PLoS One
- Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 ofMycobacterium tuberculosis
- (2013) Antonella Zumbo et al. Pathogens and Disease
- Crystal structure of a putative aspartic proteinase domain of the Mycobacterium tuberculosis cell surface antigen PE_PGRS16
- (2013) Deivanayaga V. Barathy et al. FEBS Open Bio
- Protective and survival efficacies of Rv0160c protein in murine model of Mycobacterium tuberculosis
- (2012) Susmita K. Singh et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Global Tuberculosis Control: WHO Report 2011
- (2012) AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH
- Comparative analysis of mycobacterium and related actinomycetes yields insight into the evolution of mycobacterium tuberculosis pathogenesis
- (2012) Abigail McGuire et al. BMC GENOMICS
- IS-seq: a novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes
- (2012) Alejandro Reyes et al. BMC GENOMICS
- Strong Immunogenicity and Cross-Reactivity of Mycobacterium tuberculosis ESX-5 Type VII Secretion -Encoded PE-PPE Proteins Predicts Vaccine Potential
- (2012) Fadel Sayes et al. Cell Host & Microbe
- Function Prediction and Analysis of Mycobacterium tuberculosis Hypothetical Proteins
- (2012) Gaston K. Mazandu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Unexpected Link between Lipooligosaccharide Biosynthesis and Surface Protein Release inMycobacterium marinum
- (2012) Aniek D. van der Woude et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Specific Chaperones for the Type VII Protein Secretion Pathway
- (2012) Maria H. Daleke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional Regulation of Mycobacterium tuberculosis PE/PPE Genes: A Molecular Switch to Virulence
- (2012) Krishnaveni Mohareer et al. JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY
- Cytosolic lipid inclusions formed during infection by viral and bacterial pathogens
- (2012) Matthias Stehr et al. MICROBES AND INFECTION
- The Mycobacterium avium ESX-5 PPE protein, PPE25-MAV, interacts with an ESAT-6 family Protein, MAV_2921, and localizes to the bacterial surface
- (2012) Michael McNamara et al. MICROBIAL PATHOGENESIS
- Composition of the type VII secretion system membrane complex
- (2012) Edith N. G. Houben et al. MOLECULAR MICROBIOLOGY
- Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation
- (2012) Daria Bottai et al. MOLECULAR MICROBIOLOGY
- Appropriate DevR (DosR)-Mediated Signaling Determines Transcriptional Response, Hypoxic Viability and Virulence of Mycobacterium tuberculosis
- (2012) Shyamasree De Majumdar et al. PLoS One
- Comparative Analysis of Mycobacterium tuberculosis pe and ppe Genes Reveals High Sequence Variation and an Apparent Absence of Selective Constraints
- (2012) Christopher R. E. McEvoy et al. PLoS One
- Conserved Immune Recognition Hierarchy of Mycobacterial PE/PPE Proteins during Infection in Natural Hosts
- (2012) H. Martin Vordermeier et al. PLoS One
- The Mycobacterium tuberculosis PE Proteins Rv0285 and Rv1386 Modulate Innate Immunity and Mediate Bacillary Survival in Macrophages
- (2012) Bhavana Mishra Tiwari et al. PLoS One
- Phagolysosome maturation of macrophages was reduced by PE_PGRS 62 protein expressing in Mycobacterium smegmatis and induced in IFN-γ priming
- (2012) Ying Huang et al. VETERINARY MICROBIOLOGY
- Sleeping with the Enemy: How Intracellular Pathogens Cope with a Macrophage Lifestyle
- (2012) Emily P. Thi et al. PLoS Pathogens
- Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein
- (2012) Benjamin Blasco et al. PLoS Pathogens
- The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: Perhaps more?
- (2011) Yusuf Akhter et al. BIOCHIMIE
- Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains
- (2011) Hiwa Målen et al. BMC MICROBIOLOGY
- PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis
- (2011) Raffaella Iantomasi et al. CELLULAR MICROBIOLOGY
- Mycobacterial PE/PPE Proteins at the Host-Pathogen Interface
- (2011) Samantha L. Sampson Clinical & Developmental Immunology
- Genes under positive selection in Mycobacterium tuberculosis
- (2011) Yuan Zhang et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
- The Rv1651c-encoded PE-PGRS30 protein expressed in Mycobacterium smegmatis exhibits polar localization and modulates its growth profile
- (2011) Shweta Chatrath et al. FEMS MICROBIOLOGY LETTERS
- Mycobacterium tuberculosis and the intimate discourse of a chronic infection
- (2011) David G. Russell IMMUNOLOGICAL REVIEWS
- PPE38 Modulates the Innate Immune Response and Is Required for Mycobacterium marinum Virulence
- (2011) Dandan Dong et al. INFECTION AND IMMUNITY
- Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway
- (2011) Maria H. Daleke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ins and outs of Mycobacterium tuberculosis PPE family in pathogenesis and implications for novel measures against tuberculosis
- (2011) Wanyan Deng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Characterization of Microevolution Events in Mycobacterium tuberculosis Strains Involved in Recent Transmission Clusters
- (2011) Laura Pérez-Lago et al. JOURNAL OF CLINICAL MICROBIOLOGY
- ESAT-6 Secretion-Independent Impact of ESX-1 Genes espF and espG1 on Virulence of Mycobacterium tuberculosis
- (2011) Daria Bottai et al. JOURNAL OF INFECTIOUS DISEASES
- Expression of the Mycobacterium tuberculosis PPE37 protein in Mycobacterium smegmatis induces low tumour necrosis factor alpha and interleukin 6 production in murine macrophages
- (2011) S. Daim et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway
- (2011) Gustavo A. de Souza et al. Journal of Proteomics
- Adaptation to Environmental Stimuli within the Host: Two-Component Signal Transduction Systems of Mycobacterium tuberculosis
- (2011) D. J. Bretl et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- The PE-PPE Domain in Mycobacterium Reveals a Serine α/β Hydrolase Fold and Function: An In-Silico Analysis
- (2011) Rafiya Sultana et al. PLoS One
- Functional Dissection of the PE Domain Responsible for Translocation of PE_PGRS33 across the Mycobacterial Cell Wall
- (2011) Alessandro Cascioferro et al. PLoS One
- Computational Analysis of the ESX-1 Region of Mycobacterium tuberculosis: Insights into the Mechanism of Type VII Secretion System
- (2011) Chandrani Das et al. PLoS One
- PPE_MPTR genes are differentially expressed by Mycobacterium tuberculosis in vivo
- (2011) Silvia Soldini et al. TUBERCULOSIS
- The PE and PPE proteins of Mycobacterium tuberculosis
- (2011) Sangita Mukhopadhyay et al. TUBERCULOSIS
- Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages
- (2011) Jaiyanth Daniel et al. PLoS Pathogens
- Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages
- (2010) Samradhni S Jha et al. BMC MICROBIOLOGY
- The SigF Regulon in Mycobacterium smegmatis Reveals Roles in Adaptation to Stationary Phase, Heat, and Oxidative Stress
- (2010) A. Humpel et al. JOURNAL OF BACTERIOLOGY
- Src Homology 3-interacting Domain of Rv1917c ofMycobacterium tuberculosisInduces Selective Maturation of Human Dendritic Cells by Regulating PI3K-MAPK-NF-κB Signaling and Drives Th2 Immune Responses
- (2010) Kushagra Bansal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PE_PGRS Antigens of Mycobacterium tuberculosis Induce Maturation and Activation of Human Dendritic Cells
- (2010) K. Bansal et al. JOURNAL OF IMMUNOLOGY
- Proteomic Definition of the Cell Wall ofMycobacterium tuberculosis
- (2010) Lisa M. Wolfe et al. JOURNAL OF PROTEOME RESEARCH
- Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved
- (2010) Iñaki Comas et al. NATURE GENETICS
- Portrait of a Pathogen: The Mycobacterium tuberculosis Proteome In Vivo
- (2010) Nicole A. Kruh et al. PLoS One
- Genome-Wide Screen for Mycobacterium tuberculosis Genes That Regulate Host Immunity
- (2010) Aimee M. Beaulieu et al. PLoS One
- Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis
- (2010) B. R. G. Gordon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TubercuList – 10 years after
- (2010) Jocelyne M. Lew et al. TUBERCULOSIS
- Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins
- (2010) Musa Sani et al. PLoS Pathogens
- Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region
- (2009) Christopher RE McEvoy et al. BMC EVOLUTIONARY BIOLOGY
- ESX/type VII secretion systems and their role in host–pathogen interaction
- (2009) Roxane Simeone et al. CURRENT OPINION IN MICROBIOLOGY
- The sigma factors of Mycobacterium tuberculosis: regulation of the regulators
- (2009) Preeti Sachdeva et al. FEBS Journal
- The Mycobacterium tuberculosis Sigma Factor B Is Required for Full Response to Cell Envelope Stress and Hypoxia In Vitro, but It Is Dispensable for In Vivo Growth
- (2009) P. A. Fontan et al. JOURNAL OF BACTERIOLOGY
- The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage
- (2009) S. Nair et al. JOURNAL OF IMMUNOLOGY
- PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5
- (2009) Abdallah M. Abdallah et al. MOLECULAR MICROBIOLOGY
- Multiple, independent, identical IS6110 insertions in Mycobacterium tuberculosis PPE genes
- (2009) Christopher R.E. McEvoy et al. TUBERCULOSIS
- DevR-mediated adaptive response in Mycobacterium tuberculosis H37Ra: Links to asparagine metabolism
- (2009) Vandana Malhotra et al. TUBERCULOSIS
- Identification of a Novel Multidrug Efflux Pump of Mycobacterium tuberculosis
- (2008) O. Danilchanka et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Frequent Homologous Recombination Events in Mycobacterium tuberculosis PE/PPE Multigene Families: Potential Role in Antigenic Variability
- (2008) A. Karboul et al. JOURNAL OF BACTERIOLOGY
- Rv1675c (cmr) regulates intramacrophage and cyclic AMP-induced gene expression inMycobacterium tuberculosis-complex mycobacteria
- (2008) Michaela A. Gazdik et al. MOLECULAR MICROBIOLOGY
- Mycobacterium tuberculosis PE_PGRS16 and PE_PGRS26 genetic polymorphism among clinical isolates
- (2008) Sarah Talarico et al. TUBERCULOSIS
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