Coenzyme A–mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice

Nutrient sensing and utilization: Getting to the heart of metabolic flexibility

(2016) Timothy M. Griffin et al.   BIOCHIMIE

Regulation of Pyruvate Dehydrogenase Kinase 4 in the Heart through Degradation by the Lon Protease in Response to Mitochondrial Substrate Availability

(2016) Clair Crewe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation

(2014) Mulchand S. Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria

(2013) Paul M. Rindler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation of pyruvate metabolism and human disease

(2013) Lawrence R. Gray et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rapid Inhibition of Pyruvate Dehydrogenase: An Initiating Event in High Dietary Fat-Induced Loss of Metabolic Flexibility in the Heart

(2013) Clair Crewe et al.   PLoS One

Chronic Inhibition of Pyruvate Dehydrogenase in Heart Triggers an Adaptive Metabolic Response

(2011) Kari T. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Monitoring phosphorylation of the pyruvate dehydrogenase complex

(2009) Matthew J. Rardin et al.   ANALYTICAL BIOCHEMISTRY

Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding

(2009) Jordan J. Wright et al.   CARDIOVASCULAR RESEARCH

Adaptation and Maladaptation of the Heart in Obesity

(2008) Romain Harmancey et al.   HYPERTENSION

Cardiac Remodeling in Obesity

(2008) E. Dale Abel et al.   PHYSIOLOGICAL REVIEWS

Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy

(2007) Guixiang Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY