The serine protease HtrA1 contributes to the formation of an extracellular 25-kDa apolipoprotein E fragment that stimulates neuritogenesis

Apolipoprotein E, Receptors, and Modulation of Alzheimer’s Disease

(2018) Na Zhao et al.   BIOLOGICAL PSYCHIATRY

Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice

(2016) C. Lane-Donovan et al.   JOURNAL OF NEUROSCIENCE

Apolipoprotein E-Mimetic COG1410 Reduces Acute Vasogenic Edema following Traumatic Brain Injury

(2016) Fang Cao et al.   JOURNAL OF NEUROTRAUMA

HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective

(2016) Qian Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation

(2016) Thiyagaragan M. Achariyar et al.   Molecular Neurodegeneration

An apoE-derived mimic peptide, COG1410, alleviates early brain injury via reducing apoptosis and neuroinflammation in a mouse model of subarachnoid hemorrhage

(2016) Yue Wu et al.   NEUROSCIENCE LETTERS

Loss-of-Function of HtrA1 Abrogates All-TransRetinoic Acid-Induced Osteogenic Differentiation of Mouse Adipose-Derived Stromal Cells Through Deficiencies in p70S6K Activation

(2016) Stephan Glanz et al.   STEM CELLS AND DEVELOPMENT

Determinants of amyloid fibril degradation by the PDZ protease HTRA1

(2015) Simon Poepsel et al.   Nature Chemical Biology

Expression and localization of serine protease Htra1 in neuroblastoma: correlation with cellular differentiation grade

(2014) Velia D’Angelo et al.   JOURNAL OF NEURO-ONCOLOGY

Extracellular Proteolysis of Apolipoprotein E (apoE) by Secreted Serine Neuronal Protease

(2014) Irfan Y. Tamboli et al.   PLoS One

Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased withAPOE4and Alzheimer Disease in a Transgenic Mouse Model and Human Samples

(2013) Leon M. Tai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ApoE influences amyloid-  (A ) clearance despite minimal apoE/A  association in physiological conditions

(2013) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

(2013) D. M. Holtzman et al.   Cold Spring Harbor Perspectives in Medicine

Identification of an amino-terminal fragment of apolipoprotein E4 that localizes to neurofibrillary tangles of the Alzheimer's disease brain

(2012) Troy T. Rohn et al.   BRAIN RESEARCH

Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates

(2012) Annette Tennstaedt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines

(2012) I. Dafnis et al.   NEUROSCIENCE

Dissociation of ERK signalling inhibition from the anti-amyloidogenic action of synthetic ceramide analogues

(2011) Hongyun Li et al.   CLINICAL SCIENCE

HTRA proteases: regulated proteolysis in protein quality control

(2011) Tim Clausen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Substrate-induced remodeling of the active site regulates human HTRA1 activity

(2011) Linda Truebestein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modulation of amyloid precursor protein processing by synthetic ceramide analogues

(2010) Hongyun Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Apolipoproteins in the brain: implications for neurological and psychiatric disorders

(2010) David A Elliott et al.   Clinical Lipidology

Apolipoprotein-D expression is increased during development and maturation of the human prefrontal cortex

(2009) Woojin S. Kim et al.   JOURNAL OF NEUROCHEMISTRY

Enrichment of glycopeptides for glycan structure and attachment site identification

(2009) Jonas Nilsson et al.   NATURE METHODS

Isoform-specific proteolysis of apolipoprotein-E in the brain

(2009) David A. Elliott et al.   NEUROBIOLOGY OF AGING

Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data

(2009) J. M. Ruijter et al.   NUCLEIC ACIDS RESEARCH

Contributions of the Carboxyl-Terminal Helical Segment to the Self-Association and Lipoprotein Preferences of Human Apolipoprotein E3 and E4 Isoforms†

(2008) Takaaki Sakamoto et al.   BIOCHEMISTRY

HtrA1-dependent proteolysis of TGF-β controls both neuronal maturation and developmental survival

(2008) S Launay et al.   CELL DEATH AND DIFFERENTIATION

The Apolipoprotein E-mimetic Peptide COG112 Inhibits the Inflammatory Response toCitrobacter rodentiumin Colonic Epithelial Cells by Preventing NF-κB Activation

(2008) Kshipra Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

ApoE Promotes the Proteolytic Degradation of Aβ

(2008) Qingguang Jiang et al.   NEURON