Stimulation of SIRT1 Attenuates the Level of Oxidative Stress in the Brains of APP/PS1 Double Transgenic Mice and in Primary Neurons Exposed to Oligomers of the Amyloid-β Peptide

Sirt1 Inhibits Oxidative Stress in Vascular Endothelial Cells

(2017) Weijin Zhang et al.   Oxidative Medicine and Cellular Longevity

Alzheimer's disease and metabolic syndrome: A link from oxidative stress and inflammation to neurodegeneration

(2017) Eduardo Rojas-Gutierrez et al.   SYNAPSE

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain

(2016) J. Sepulcre et al.   JOURNAL OF NEUROSCIENCE

Age, APOE and sex: Triad of risk of Alzheimer’s disease

(2016) Brandalyn C. Riedel et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders

(2016) Henryk Jęśko et al.   NEUROCHEMICAL RESEARCH

Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy

(2016) Liang Wang et al.   JAMA Neurology

Detection of Alzheimer’s disease amyloid-beta plaque deposition by deep brain impedance profiling

(2015) Amélie Béduer et al.   Journal of Neural Engineering

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

SIRT1 in the brain—connections with aging-associated disorders and lifespan

(2015) Fanny Ng   Frontiers in Cellular Neuroscience

Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer’s disease

(2014) Michael A Castello et al.   BMC Neurology

Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β

(2014) Hye Rin Lee et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Distinct Patterns of Sirtuin Expression During Progression of Alzheimer’s Disease

(2014) Mirjam I. Lutz et al.   NEUROMOLECULAR MEDICINE

Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease?

(2014) Ilaria Dal Prà et al.   NEUROSCIENTIST

The Roles of Biomarkers of Oxidative Stress and Antioxidant in Alzheimer’s Disease: A Systematic Review

(2014) Ya-Ting Chang et al.   Biomed Research International

Sirtuin deacetylases in neurodegenerative diseases of aging

(2013) Adrianna Z Herskovits et al.   CELL RESEARCH

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

SIRT1 and SIRT2: emerging targets in neurodegeneration

(2013) Gizem Donmez et al.   EMBO Molecular Medicine

trans-Resveratrol in Gnetum gnemon Protects against Oxidative-Stress-Induced Endothelial Senescence

(2013) Hidetaka Ota et al.   JOURNAL OF NATURAL PRODUCTS

Immunotherapy against amyloid pathology in Alzheimer's disease

(2013) Daniela Galimberti et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Therapeutics of Alzheimer's disease: Past, present and future

(2013) R. Anand et al.   NEUROPHARMACOLOGY

Resveratrol Inhibits β-Amyloid-Induced Neuronal Apoptosis through Regulation of SIRT1-ROCK1 Signaling Pathway

(2013) Xiaowen Feng et al.   PLoS One

Sirtuin1: A Promising Serum Protein Marker for Early Detection of Alzheimer’s Disease

(2013) Rahul Kumar et al.   PLoS One

Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress

(2013) Yusuke S. Hori et al.   PLoS One

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

Sirtuins in cognitive ageing and Alzheimerʼs disease

(2012) Nady Braidy et al.   CURRENT OPINION IN PSYCHIATRY

SIRT1: new avenues of discovery for disorders of oxidative stress

(2012) Zhao Zhong Chong et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Impaired mitochondrial function in psychiatric disorders

(2012) Husseini Manji et al.   NATURE REVIEWS NEUROSCIENCE

Postsynaptic Receptors for Amyloid-β Oligomers as Mediators of Neuronal Damage in Alzheimer’s Disease

(2012) Margarita C. Dinamarca et al.   Frontiers in Physiology

Fine Tuning Our Cellular Factories: Sirtuins in Mitochondrial Biology

(2011) Lei Zhong et al.   Cell Metabolism

Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is ‘too big to fail’

(2011) Rudy J Castellani et al.   JOURNAL OF PATHOLOGY

Peripheral markers in neurodegenerative patients and their first-degree relatives

(2011) Diana Olga Cristalli et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Sirtuins in Neurodegenerative Diseases: A Biological-Chemical Perspective

(2011) Aparna Raghavan et al.   Neurodegenerative Diseases

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated Dendritic Spine Remodeling Produced by BDNF

(2010) Andrea C. Paula-Lima et al.   ANTIOXIDANTS & REDOX SIGNALING

RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10

(2010) Gizem Donmez et al.   CELL

Oxidative stress: Biomarkers and novel therapeutic pathways

(2010) Kenneth Maiese et al.   EXPERIMENTAL GERONTOLOGY

Induction of Manganese Superoxide Dismutase by Nuclear Translocation and Activation of SIRT1 Promotes Cell Survival in Chronic Heart Failure

(2010) Masaya Tanno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nerve growth factor attenuates oxidant-induced β-amyloid neurotoxicity in sporadic Alzheimer’s disease cybrids

(2010) Isaac G. Onyango et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of Vascular Aging: New Perspectives

(2010) Z. Ungvari et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Neuropathology of Alzheimer's Disease

(2010) Daniel P. Perl   MOUNT SINAI JOURNAL OF MEDICINE

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition

(2010) Andrei G. Vlassenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of Sirt1: At the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology

(2009) Jun Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Cross-talk between oxidative stress and modifications of cholinergic and glutaminergic receptors in the pathogenesis of Alzheimer's disease1

(2008) Zhi-zhong GUAN   ACTA PHARMACOLOGICA SINICA

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

(2008) Kazuhiro Hasegawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enhanced Tolerance against Early and Late Apoptotic Oxidative Stress in Mammalian Neurons through Nicotinamidase and Sirtuin Mediated Pathways

(2008) Zhao Chong et al.   CURRENT NEUROVASCULAR RESEARCH

Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease

(2008) Carl Julien et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY