Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model

Brown adipose tissue is associated with systemic concentrations of peptides secreted from the gastrointestinal system and involved in appetite regulation

(2017) Maria Chondronikola et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation

(2017) Ken Howick et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Compulsive-Like Sufentanil Vapor Self-Administration in Rats

(2017) Janaina C M Vendruscolo et al.   NEUROPSYCHOPHARMACOLOGY

Obesity-prone high-fat-fed rats reduce caloric intake and adiposity and gain more fat-free mass when allowed to self-select protein from carbohydrate:fat intake

(2016) Dalila Azzout-Marniche et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Rodent models in neuroscience research: is it a rat race?

(2016) Bart Ellenbroek et al.   Disease Models & Mechanisms

A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons

(2016) Gemma Navarro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced intake of carbohydrate prevents the development of obesity and impaired glucose metabolism in ghrelin O-acyltransferase knockout mice

(2016) Tetsuya Kouno et al.   PEPTIDES

Rats with a truncated ghrelin receptor (GHSR) do not respond to ghrelin, and show reduced intake of palatable, high-calorie food

(2016) Harry MacKay et al.   PHYSIOLOGY & BEHAVIOR

The suppression of ghrelin signaling mitigates age-associated thermogenic impairment

(2016) Ligen Lin et al.   Aging-US

Centrally Administered Ghrelin Acutely Influences Food Choice in Rodents

(2016) Erik Schéle et al.   PLoS One

Cocaine self-administration punished by intravenous histamine in adolescent and adult rats

(2015) Nathan A. Holtz et al.   BEHAVIOURAL PHARMACOLOGY

Ghrelin’s Role in the Hypothalamic-Pituitary-Adrenal Axis Stress Response: Implications for Mood Disorders

(2015) Sarah J. Spencer et al.   BIOLOGICAL PSYCHIATRY

Can Brown Fat Win the Battle Against White Fat?

(2015) Sawsan Elattar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ghrelin signaling is not essential for sugar or fat conditioned flavor preferences in mice

(2015) Anthony Sclafani et al.   PHYSIOLOGY & BEHAVIOR

Ghrelin in psychiatric disorders – A review

(2015) Dirk Alexander Wittekind et al.   PSYCHONEUROENDOCRINOLOGY

The effect of high-fat diet on rat’s mood, feeding behavior and response to stress

(2015) S Aslani et al.   Translational Psychiatry

Ghrelin

(2015) T.D. Müller et al.   Molecular Metabolism

The role of ghrelin in addiction: a review

(2014) Vassilis N. Panagopoulos et al.   PSYCHOPHARMACOLOGY

The role of ghrelin in drug and natural reward

(2013) Valentina Vengeliene   ADDICTION BIOLOGY

Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics

(2013) Clarissa C. Parker et al.   NEUROPHARMACOLOGY

GHS-R1a constitutive activity and its physiological relevance

(2013) Yves Mear et al.   Frontiers in Neuroscience

Attenuation of cocaine-induced locomotor sensitization in rats sustaining genetic or pharmacologic antagonism of ghrelin receptors

(2011) P. Shane Clifford et al.   ADDICTION BIOLOGY

Food intake and interdigestive gastrointestinal motility in ghrelin receptor mutant rats

(2011) Mehmet Bülbül et al.   JOURNAL OF GASTROENTEROLOGY

The truncated ghrelin receptor polypeptide (GHS-R1b) is localized in the endoplasmic reticulum where it forms heterodimers with ghrelin receptors (GHS-R1a) to attenuate their cell surface expression

(2011) Kevin B.S. Chow et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Physiological role of ghrelin as revealed by the ghrelin and GOAT knockout mice

(2011) Kihwa Kang et al.   PEPTIDES

Physiological roles revealed by ghrelin and ghrelin receptor deficient mice

(2011) Rosie G. Albarran-Zeckler et al.   PEPTIDES

Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging

(2011) Xiaojun Ma et al.   PLoS One

Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice

(2010) Shane Clifford et al.   ADDICTION BIOLOGY

Role of the ghrelin system in alcoholism: Acting on the growth hormone secretagogue receptor to treat alcohol-related diseases

(2010) L. Leggio   DRUG NEWS & PERSPECTIVES

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice

(2010) T.-J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental rat models to study the metabolic syndrome

(2009) Amaya Aleixandre de Artiñano et al.   BRITISH JOURNAL OF NUTRITION

Ghrelin in the regulation of body weight and metabolism

(2009) T.R. Castañeda et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Requirement of central ghrelin signaling for alcohol reward

(2009) E. Jerlhag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats

(2009) Asuka Mano-Otagiri et al.   REGULATORY PEPTIDES

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state

(2008) Heather N. Richardson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Ghrelin octanoylation mediated by an orphan lipid transferase

(2008) J. A. Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA