Protective Effects of 6-(Methylsulfinyl)hexyl Isothiocyanate on Aβ1-42-Induced Cognitive Deficit, Oxidative Stress, Inflammation, and Apoptosis in Mice

Rosmarinic acid attenuates β-amyloid-induced oxidative stress via Akt/GSK-3β/Fyn-mediated Nrf2 activation in PC12 cells

(2018) Hua Rong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced inflammation and oxidative stress

(2018) Ming-Chang Chiang et al.   NEUROCHEMISTRY INTERNATIONAL

Methyl Salicylate Lactoside Protects Neurons Ameliorating Cognitive Disorder Through Inhibiting Amyloid Beta-Induced Neuroinflammatory Response in Alzheimer’s Disease

(2018) Jinze Li et al.   Frontiers in Aging Neuroscience

Neuroprotective Effect of Caffeic Acid Phenethyl Ester in A Mouse Model of Alzheimer’s Disease Involves Nrf2/HO-1 Pathway

(2018) Fabiana Morroni et al.   Aging and Disease

Genetic reduction of Nrf2 exacerbates cognitive deficits in a mouse model of Alzheimer’s disease

(2017) Caterina Branca et al.   HUMAN MOLECULAR GENETICS

Neuroprotective and Anti-Inflammatory Activities of Allyl Isothiocyanate through Attenuation of JNK/NF-κB/TNF-α Signaling

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modulation of AβPP and GSK3β by Endoplasmic Reticulum Stress and Involvement in Alzheimer’s Disease

(2017) Xin-jun Liu et al.   JOURNAL OF ALZHEIMERS DISEASE

Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology

(2016) Elodie Martin et al.   AGING CELL

The Proteasome and Oxidative Stress in Alzheimer's Disease

(2016) Vicent Bonet-Costa et al.   ANTIOXIDANTS & REDOX SIGNALING

Early effects of Aβ 1-42 oligomers injection in mice: Involvement of PI3K/Akt/GSK3 and MAPK/ERK1/2 pathways

(2016) Fabiana Morroni et al.   BEHAVIOURAL BRAIN RESEARCH

Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease

(2016) Mudasir Maqbool et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Isothiocyanates Are Promising Compounds against Oxidative Stress, Neuroinflammation and Cell Death that May Benefit Neurodegeneration in Parkinson’s Disease

(2016) Giulia Sita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Acceleration of Amyloidosis by Inflammation in the Amyloid-Beta Marmoset Monkey Model of Alzheimer’s Disease

(2016) Ingrid H. Philippens et al.   JOURNAL OF ALZHEIMERS DISEASE

Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways

(2016) Thomas M. Sanderson et al.   JOURNAL OF NEUROCHEMISTRY

Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer’s disease models

(2016) Stuart A Lipton et al.   Cell Death & Disease

Antibacterial Activities of Wasabi against Escherichia coli O157:H7 and Staphylococcus aureus

(2016) Zhongjing Lu et al.   Frontiers in Microbiology

The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer

(2015) Shu-Wen Hsuan et al.   EUROPEAN JOURNAL OF NUTRITION

Neuroglobin Attenuates Beta Amyloid-Induced Apoptosis Through Inhibiting Caspases Activity by Activating PI3K/Akt Signaling Pathway

(2015) Yu Li et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

In Vivo Application of beta Amyloid Oligomers: A Simple Tool to Evaluate Mechanisms of Action and New Therapeutic Approaches

(2015) Claudia Balducci et al.   CURRENT PHARMACEUTICAL DESIGN

Neuroprotection by 6-(methylsulfinyl)hexyl isothiocyanate in a 6-hydroxydopamine mouse model of Parkinson׳s disease

(2014) Fabiana Morroni et al.   BRAIN RESEARCH

Neuroprotection by Association of Palmitoylethanolamide with Luteolin in Experimental Alzheimer’s Disease Models: The Control of Neuroinflammation

(2014) Irene Paterniti et al.   CNS & Neurological Disorders-Drug Targets

Antiinflammatory activity of glucomoringin isothiocyanate in a mouse model of experimental autoimmune encephalomyelitis

(2014) Maria Galuppo et al.   FITOTERAPIA

Sulforaphane alleviates scopolamine-induced memory impairment in mice

(2014) Siyoung Lee et al.   PHARMACOLOGICAL RESEARCH

Glycogen Synthase Kinase 3 Regulates Cell Death and Survival Signaling in Tumor Cells under Redox Stress

(2014) Roberta Venè et al.   NEOPLASIA

6-Methylsulfinylhexyl isothiocyanate modulates endothelial cell function and suppresses leukocyte adhesion

(2013) Takayuki Okamoto et al.   Journal of Natural Medicines

The roles of protein kinases in learning and memory

(2013) K. P. Giese et al.   LEARNING & MEMORY

Neuroinflammation: The role and consequences

(2013) Monty Lyman et al.   NEUROSCIENCE RESEARCH

Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease

(2013) Fabiana Morroni et al.   NEUROTOXICOLOGY

Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model

(2012) Hyunjin Vincent Kim et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

A molecular view on signal transduction by the apoptosome

(2012) Thomas F. Reubold et al.   CELLULAR SIGNALLING

Selectively Silencing GSK-3 Isoforms Reduces Plaques and Tangles in Mouse Models of Alzheimer's Disease

(2012) D. E. Hurtado et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein Protects Neurons from Apoptosis Downstream of Free-Radical Production Through Modulation of the MAPK Signalling Pathway

(2012) Ruth E. J. Musgrove et al.   NEUROTOXICITY RESEARCH

Time-Course and Regional Analyses of the Physiopathological Changes Induced after Cerebral Injection of an Amyloid β Fragment in Rats

(2011) Charleine Zussy et al.   AMERICAN JOURNAL OF PATHOLOGY

The molecular basis that unifies the metabolism, cellular uptake and chemopreventive activities of dietary isothiocyanates

(2011) Y. Zhang   CARCINOGENESIS

Dynamics of Nrf2 and Keap1 in ARE-MediatedNQO1Expression by Wasabi 6-(Methylsulfinyl)hexyl Isothiocyanate

(2011) De-Xing Hou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

(2011) H. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of caspases in Alzheimer’s disease; potential novel therapeutic opportunities

(2010) Troy T. Rohn   APOPTOSIS

Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme

(2010) Zhang Ping et al.   BRAIN RESEARCH

ERK in Learning and Memory: A Review of Recent Research

(2010) Sheng Peng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extracellular HMGB1 Released by NMDA Treatment Confers Neuronal Apoptosis via RAGE-p38 MAPK/ERK Signaling Pathway

(2010) Seung-Woo Kim et al.   NEUROTOXICITY RESEARCH

Oxidative stress mediates the pathogenic effect of different Alzheimer’s disease risk factors

(2010) Guglielmotto   Frontiers in Aging Neuroscience

Peoniflorin attentuates Aβ(1–42)-mediated neurotoxicity by regulating calcium homeostasis and ameliorating oxidative stress in hippocampus of rats

(2009) Shu-Zhi Zhong et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

Cyanidin 3-O-glucopyranoside protects and rescues SH-SY5Y cells against amyloid-beta peptide-induced toxicity

(2008) Andrea Tarozzi et al.   NEUROREPORT