Non-Coding RNA in the Pathogenesis, Progression and Treatment of Hypertension

Association of rs2271037 and rs3749585 polymorphisms in CORIN with susceptibility to hypertension in a Chinese Han population: A case-control study

(2018) Yan-li Chen et al.   GENE

Understanding the role of genetics in hypertension

(2017) Riyaz S. Patel et al.   EUROPEAN HEART JOURNAL

AK098656, a Novel Vascular Smooth Muscle Cell–Dominant Long Noncoding RNA, Promotes HypertensionNovelty and Significance

(2017) Ling Jin et al.   HYPERTENSION

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

(2017) Paul K. Whelton et al.   HYPERTENSION

Plasma expression level of miRNA let-7 is positively correlated with carotid intima-media thickness in patients with essential hypertension

(2017) Y-q Huang et al.   JOURNAL OF HUMAN HYPERTENSION

Profiles of long noncoding RNAs in hypertensive rats

(2017) Qing-Ping Yao et al.   JOURNAL OF HYPERTENSION

Outcomes of Intensive Blood Pressure Lowering in Older Hypertensive Patients

(2017) Chirag Bavishi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

micro-RNA screening and prediction model construction for diagnosis of salt-sensitive essential hypertension

(2017) Han Qi et al.   MEDICINE

Downregulation of microRNA-34b is responsible for the elevation of blood pressure in spontaneously hypertensive rats

(2017) Fan Yang et al.   Molecular Medicine Reports

The Function and Therapeutic Potential of Long Non-coding RNAs in Cardiovascular Development and Disease

(2017) Clarissa P.C. Gomes et al.   Molecular Therapy-Nucleic Acids

Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine

(2017) Chiranjib Chakraborty et al.   Molecular Therapy-Nucleic Acids

The Role of MicroRNAs in Arterial Stiffness and Arterial Calcification. An Update and Review of the Literature

(2017) Sideris Nanoudis et al.   Frontiers in Genetics

Loss of Vascular Myogenic Tone in miR-143/145 Knockout Mice Is Associated With Hypertension-Induced Vascular Lesions in Small Mesenteric Arteries

(2017) Johan Holmberg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Global Disparities of Hypertension Prevalence and ControlClinical Perspective

(2016) Katherine T. Mills et al.   CIRCULATION

Polymorphisms in the long non-coding RNA CDKN2B-AS1 may contribute to higher systolic blood pressure levels in hypertensive patients

(2016) Burcu Bayoglu et al.   CLINICAL BIOCHEMISTRY

Role of MicroRNA in Endothelial Dysfunction and Hypertension

(2016) Miruna Nemecz et al.   CURRENT HYPERTENSION REPORTS

The mir-221/222 Cluster is a Key Player in Vascular Biology via the Fine-Tuning of Endothelial Cell Physiology

(2016) Tanja Celic et al.   Current Vascular Pharmacology

Long Noncoding RNA-GAS5Novelty and Significance

(2016) Yang-Ning-Zhi Wang et al.   HYPERTENSION

Expression and methylation of circulating microRNA-510 in essential hypertension

(2016) Ramalingam Krishnan et al.   HYPERTENSION RESEARCH

Low Levels of MicroRNA-21 Are a Marker of Reduced Arterial Stiffness in Well-Controlled Hypertension

(2016) Fragiskos Parthenakis et al.   Journal of Clinical Hypertension

Circulating miR-92a expression level in patients with essential hypertension: a potential marker of atherosclerosis

(2016) Y Huang et al.   JOURNAL OF HUMAN HYPERTENSION

Long noncoding RNA Chast promotes cardiac remodeling

(2016) Janika Viereck et al.   Science Translational Medicine

miR-155 functions downstream of angiotensin II receptor subtype 1 and calcineurin to regulate cardiac hypertrophy

(2016) Yong Yang et al.   Experimental and Therapeutic Medicine

Racial differences in microRNA and gene expression in hypertensive women

(2016) Douglas F. Dluzen et al.   Scientific Reports

Treatment of Hypertension in Patients With Coronary Artery Disease

(2015) Clive Rosendorff et al.   CIRCULATION

Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis

(2015) Johan M. Lorenzen et al.   EUROPEAN HEART JOURNAL

Differentiation of mammary tumors and reduction in metastasis uponMalat1lncRNA loss

(2015) Gayatri Arun et al.   GENES & DEVELOPMENT

Hypertension

(2015) Neil R Poulter et al.   LANCET

siRNA Versus miRNA as Therapeutics for Gene Silencing

(2015) Jenny K W Lam et al.   Molecular Therapy-Nucleic Acids

Non-coding RNA: what is functional and what is junk?

(2015) Alexander F. Palazzo et al.   Frontiers in Genetics

Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci

(2014) Vinicius Tragante et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identification and Initial Functional Characterization of a Human Vascular Cell–Enriched Long Noncoding RNA

(2014) Robert D. Bell et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes

(2014) Ugur Gezer et al.   CELL BIOLOGY INTERNATIONAL

Long Noncoding RNA MALAT1 Regulates Endothelial Cell Function and Vessel Growth

(2014) Katharina M. Michalik et al.   CIRCULATION RESEARCH

Unacylated Ghrelin Induces Oxidative Stress Resistance in a Glucose Intolerance and Peripheral Artery Disease Mouse Model by Restoring Endothelial Cell miR-126 Expression

(2014) Gabriele Togliatto et al.   DIABETES

Competing targets of microRNA-608 affect anxiety and hypertension

(2014) G. Hanin et al.   HUMAN MOLECULAR GENETICS

Endothelial Dysfunction and Hypertension

(2014) Ralf P. Brandes   HYPERTENSION

MicroRNA-505 identified from patients with essential hypertension impairs endothelial cell migration and tube formation

(2014) Qinbo Yang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Angiotensin II-regulated microRNA 483-3p directly targets multiple components of the renin–angiotensin system

(2014) Jacqueline R. Kemp et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-9 and microRNA-126 expression levels in patients with essential hypertension: potential markers of target-organ damage

(2014) Joanna E. Kontaraki et al.   Journal of the American Society of Hypertension

Inhibition of miR-25 improves cardiac contractility in the failing heart

(2014) Christine Wahlquist et al.   NATURE

Defining functional DNA elements in the human genome

(2014) M. Kellis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells

(2014) Fatiha Tabet et al.   Nature Communications

AMP-Activated Protein Kinase Regulates Endothelial Cell Angiotensin-Converting Enzyme Expression via p53 and the Post-Transcriptional Regulation of microRNA-143/145

(2013) Karin Kohlstedt et al.   CIRCULATION RESEARCH

Urinary exosome miRNome analysis and its applications to salt sensitivity of blood pressure

(2013) John J. Gildea et al.   CLINICAL BIOCHEMISTRY

MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways

(2013) Henry S. Cheng et al.   EMBO Molecular Medicine

Overexpression of microRNA-145 in atherosclerotic plaques from hypertensive patients

(2013) Donato Santovito et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension

(2013) R. S. Friese et al.   HUMAN MOLECULAR GENETICS

A Novel Interaction Between Sympathetic Overactivity and Aberrant Regulation of Renin by miR-181a in BPH/2J Genetically Hypertensive Mice

(2013) Kristy L. Jackson et al.   HYPERTENSION

Angiotensin II Regulates microRNA-132/-212 in Hypertensive Rats and Humans

(2013) Tilde Eskildsen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Atrial natriuretic peptide is negatively regulated by microRNA-425

(2013) Pankaj Arora et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential expression of vascular smooth muscle-modulating microRNAs in human peripheral blood mononuclear cells: novel targets in essential hypertension

(2013) J E Kontaraki et al.   JOURNAL OF HUMAN HYPERTENSION

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122

(2013) Luca F. R. Gebert et al.   NUCLEIC ACIDS RESEARCH

RNAi-based nanomedicines for targeted personalized therapy

(2012) Ala Daka et al.   ADVANCED DRUG DELIVERY REVIEWS

Essential Role of MicroRNA-155 in Regulating Endothelium-Dependent Vasorelaxation by Targeting Endothelial Nitric Oxide Synthase

(2012) Hai-Xiang Sun et al.   HYPERTENSION

Hypertensive emergencies are associated with elevated markers of inflammation, coagulation, platelet activation and fibrinolysis

(2012) U Derhaschnig et al.   JOURNAL OF HUMAN HYPERTENSION

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

SNPs in MicroRNA Binding Sites in 3′-UTRs of RAAS Genes Influence Arterial Blood Pressure and Risk of Myocardial Infarction

(2011) A Yaël Nossent et al.   AMERICAN JOURNAL OF HYPERTENSION

Signature microRNA Expression Profile of Essential Hypertension and Its Novel Link to Human Cytomegalovirus Infection

(2011) Shuqiang Li et al.   CIRCULATION

A Common Genetic Variant in the 3′-UTR of Vacuolar H + -ATPase ATP6V0A1 Creates a Micro-RNA Motif to Alter Chromogranin A Processing and Hypertension Risk

(2011) Zhiyun Wei et al.   Circulation-Cardiovascular Genetics

MicroRNAs in Hypertension: Mechanisms and Therapeutic Targets

(2011) Sándor Bátkai et al.   CURRENT HYPERTENSION REPORTS

Gene Expression Profiling Reveals Renin mRNA Overexpression in Human Hypertensive Kidneys and a Role for MicroRNAs

(2011) Francine Z. Marques et al.   HYPERTENSION

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interplay Between miR-155, AT1R A1166C Polymorphism, and AT1R Expression in Young Untreated Hypertensives

(2010) G. Ceolotto et al.   AMERICAN JOURNAL OF HYPERTENSION

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

microRNA-222 Controls Neovascularization by Regulating Signal Transducer and Activator of Transcription 5A Expression

(2010) Patrizia Dentelli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans

(2010) Rebecca T Marquez et al.   LABORATORY INVESTIGATION

Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

(2009) Thomas Boettger et al.   JOURNAL OF CLINICAL INVESTIGATION

Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4′-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer

(2009) Kees Fluiter et al.   Molecular BioSystems

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

Microribonucleic Acid-21 Increases Aldosterone Secretion and Proliferation in H295R Human Adrenocortical Cells

(2008) Damian G. Romero et al.   ENDOCRINOLOGY

Mechanistic insights into the link between a polymorphism of the 3′UTR of theSLC7A1gene and hypertension

(2008) Zhiyong Yang et al.   HUMAN MUTATION

Kidney in Hypertension

(2008) Thomas M. Coffman et al.   HYPERTENSION

MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

(2008) T. A. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importance of hemodynamic forces as signals for exercise-induced changes in endothelial cell phenotype

(2007) M. Harold Laughlin et al.   JOURNAL OF APPLIED PHYSIOLOGY