The Role of MicroRNAs in Arterial Stiffness and Arterial Calcification. An Update and Review of the Literature

The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2

(2017) Wenhong Jiang et al.   Biomed Research International

Microrna 143–145 Deficiency Impairs Vascular Function

(2017) G.D. Norata et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification

(2017) Jianghua Liu et al.   PLoS One

miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling

(2017) Daijiro Hori et al.   PLoS One

miR-135a Suppresses Calcification in Senescent VSMCs by Regulating KLF4/STAT3 Pathway

(2016) Lin Lin et al.   Current Vascular Pharmacology

Phenotypic switching of vascular smooth muscle cells in the ‘normal region’ of aorta from atherosclerosis patients is regulated bymiR-145

(2016) Yu-nan Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways

(2016) Christopher J. Nicholson et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-19b controls cardiac fibroblast proliferation and migration

(2016) Chongjun Zhong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Low Levels of MicroRNA-21 Are a Marker of Reduced Arterial Stiffness in Well-Controlled Hypertension

(2016) Fragiskos Parthenakis et al.   Journal of Clinical Hypertension

miRNA-145 inhibits VSMC proliferation by targeting CD40

(2016) Xin Guo et al.   Scientific Reports

MicroRNA-15b/16 Attenuates Vascular Neointima Formation by Promoting the Contractile Phenotype of Vascular Smooth Muscle Through Targeting YAPSignificance

(2015) Fei Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Down-regulation of miR-23b induces phenotypic switching of vascular smooth muscle cellsin vitroandin vivo

(2015) Claudio Iaconetti et al.   CARDIOVASCULAR RESEARCH

Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis

(2015) Johan M. Lorenzen et al.   EUROPEAN HEART JOURNAL

MicroRNA-155 modulates the proliferation of vascular smooth muscle cells by targeting endothelial nitric oxide synthase

(2015) JUN ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Matrix metalloproteinase interactions with collagen and elastin

(2015) Steven R. Van Doren   MATRIX BIOLOGY

MicroRNA-765 influences arterial stiffness through modulating apelin expression

(2015) Yi-Chu Liao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Inhibition of microRNA-25 by tumor necrosis factor α is critical in the modulation of vascular smooth muscle cell proliferation

(2015) LICHUN QI et al.   Molecular Medicine Reports

MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C

(2015) Zhiliang Xu et al.   Scientific Reports

Runx2/miR-3960/miR-2861 Positive Feedback Loop Is Responsible for Osteogenic Transdifferentiation of Vascular Smooth Muscle Cells

(2015) Zhu-Ying Xia et al.   Biomed Research International

Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling

(2015) Dmitry A. Chistiakov et al.   Biomed Research International

“Smooth Muscle Cell Stiffness Syndrome”—Revisiting the Structural Basis of Arterial Stiffness

(2015) Nancy L. Sehgel et al.   Frontiers in Physiology

miR-599 Inhibits Vascular Smooth Muscle Cells Proliferation and Migration by Targeting TGFB2

(2015) Baodong Xie et al.   PLoS One

Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function?

(2014) Yuan Z. Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

miRNA-221 and miRNA-222 synergistically function to promote vascular calcification

(2014) N. C. W. Mackenzie et al.   CELL BIOCHEMISTRY AND FUNCTION

MicroRNA-205 Regulates the Calcification and Osteoblastic Differentiation of Vascular Smooth Muscle Cells

(2014) Weiwei Qiao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA-365 Inhibits Vascular Smooth Muscle Cell Proliferation through Targeting Cyclin D1

(2014) Peng Zhang et al.   International Journal of Medical Sciences

MicroRNA-155 inhibits angiotensin II-induced vascular smooth muscle cell proliferation

(2014) Li-xia Yang et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

MicroRNA-146a and -21 cooperate to regulate vascular smooth muscle cell proliferation via modulation of the Notch signaling pathway

(2014) JIAN CAO et al.   Molecular Medicine Reports

IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependent

(2014) Shunsuke Fukuyo et al.   RHEUMATOLOGY

HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells

(2014) Fatiha Tabet et al.   Nature Communications

miR-18a-5p MicroRNA Increases Vascular Smooth Muscle Cell Differentiation by Downregulating Syndecan4

(2014) Hae Jin Kee et al.   Korean Circulation Journal

Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension

(2013) Nancy L. Sehgel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

miR181a protects against angiotensin II-induced osteopontin expression in vascular smooth muscle cells

(2013) Ebony Washington Remus et al.   ATHEROSCLEROSIS

Downregulation of MicroRNA-19b Contributes to Angiotensin II-Induced Overexpression of Connective Tissue Growth Factor in Cardiomyocytes

(2013) Song Gao et al.   CARDIOLOGY

MiR-490-3p modulates the proliferation of vascular smooth muscle cells induced by ox-LDL through targeting PAPP-A

(2013) Yufa Sun et al.   CARDIOVASCULAR RESEARCH

MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1

(2013) Pan Li et al.   CARDIOVASCULAR RESEARCH

MicroRNA-663 Regulates Human Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Neointimal Formation

(2013) Pan Li et al.   CIRCULATION RESEARCH

miR-663 and the miRaculous Vascular Smooth Muscle Phenotypic Switch

(2013) Thomas Korff et al.   CIRCULATION RESEARCH

MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts

(2013) Daren Wang et al.   CIRCULATION RESEARCH

microRNAs in the onset and development of cardiovascular disease: Figure 1

(2013) Kasey C. Vickers et al.   CLINICAL SCIENCE

MiR-133a Modulates Osteogenic Differentiation of Vascular Smooth Muscle Cells

(2013) Xiao-Bo Liao et al.   ENDOCRINOLOGY

B cell translocation gene, a direct target of miR-142-5p, inhibits vascular smooth muscle cell proliferation by down-regulating cell cycle progression

(2013) Hae Jin Kee et al.   FEBS LETTERS

Down-Regulation of miR-96 by Bone Morphogenetic Protein Signaling is Critical for Vascular Smooth Muscle Cell Phenotype Modulation

(2013) Sunghwan Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Bone Morphogenetic Protein‐2 Decreases MicroRNA‐30b and MicroRNA‐30c to Promote Vascular Smooth Muscle Cell Calcification

(2013) Joshua A. F. Balderman et al.   Journal of the American Heart Association

Upregulation of a Disintegrin and Metalloproteinase With Thrombospondin Motifs-7 by miR-29 Repression Mediates Vascular Smooth Muscle Calcification

(2012) Yaoyao Du et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-195 regulates vascular smooth muscle cell phenotype and prevents neointimal formation

(2012) Yung-Song Wang et al.   CARDIOVASCULAR RESEARCH

MicroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo

(2012) R.-R. Cui et al.   CARDIOVASCULAR RESEARCH

Essential Role of MicroRNA-155 in Regulating Endothelium-Dependent Vasorelaxation by Targeting Endothelial Nitric Oxide Synthase

(2012) Hai-Xiang Sun et al.   HYPERTENSION

Src modulates contractile vascular smooth muscle function via regulation of focal adhesions

(2012) Jianghong Min et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury

(2012) Alison J. Kriegel et al.   PHYSIOLOGICAL GENOMICS

Inorganic Phosphate Accelerates the Migration of Vascular Smooth Muscle Cells: Evidence for the Involvement of miR-223

(2012) Ashraf Yusuf Rangrez et al.   PLoS One

Elastin in Large Artery Stiffness and Hypertension

(2012) Jessica E. Wagenseil et al.   Journal of Cardiovascular Translational Research

MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension

(2011) W.-H. Wu et al.   AMERICAN JOURNAL OF HYPERTENSION

miR-125b Regulates Calcification of Vascular Smooth Muscle Cells

(2011) Claudia Goettsch et al.   AMERICAN JOURNAL OF PATHOLOGY

Micromanaging Vascular Smooth Muscle Cell Differentiation and Phenotypic Modulation

(2011) Brandi N. Davis-Dusenbery et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-21 Regulates Vascular Smooth Muscle Cell Function via Targeting Tropomyosin 1 in Arteriosclerosis Obliterans of Lower Extremities

(2011) Mian Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of MicroRNA-29 Enhances Elastin Levels in Cells Haploinsufficient for Elastin and in Bioengineered Vessels—Brief Report

(2011) Pei Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Smooth Muscle Cell Proliferation Is Influenced by let-7d MicroRNA and Its Interaction With KRAS

(2011) Man-Li Yu et al.   CIRCULATION JOURNAL

MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch In Vitro and Vascular Remodeling In Vivo

(2011) Daniele Torella et al.   CIRCULATION RESEARCH

Down-regulation of Krüppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-β and Bone Morphogenetic Protein 4

(2011) Brandi N. Davis-Dusenbery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-specific effects of miR-221/222 in vessels: Molecular mechanism and therapeutic application

(2011) Xiaojun Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Suppression of microRNA-29 Expression by TGF- 1 Promotes Collagen Expression and Renal Fibrosis

(2011) B. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNAs Differentially Expressed in Postnatal Aortic Development Downregulate Elastin via 3′ UTR and Coding-Sequence Binding Sites

(2011) Claus Eric Ott et al.   PLoS One

Arterial stiffness: a brief review

(2010) Najeeb A Shirwany et al.   ACTA PHARMACOLOGICA SINICA

Matrix Metalloproteinase 2 and 9 Dysfunction Underlie Vascular Stiffness in Circadian Clock Mutant Mice

(2010) Ciprian B. Anea et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Induction of MicroRNA-1 by Myocardin in Smooth Muscle Cells Inhibits Cell Proliferation

(2010) Jie Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Arterial Stiffness and Cardiovascular Events

(2010) Gary F. Mitchell et al.   CIRCULATION

miR-10a Contributes to Retinoid Acid-induced Smooth Muscle Cell Differentiation

(2010) Huarong Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-26a is a novel regulator of vascular smooth muscle cell function

(2010) Nicholas J. Leeper et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA-1 Regulates Smooth Muscle Cell Differentiation by Repressing Kruppel-Like Factor 4

(2010) Changqing Xie et al.   STEM CELLS AND DEVELOPMENT

MicroRNAs: a novel class of potential therapeutic targets for cardiovascular diseases

(2009) Zhen-wei Pan et al.   ACTA PHARMACOLOGICA SINICA

A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

(2009) Xiaojun Liu et al.   CIRCULATION RESEARCH

Molecular basis for antagonism between PDGF and the TGFβ family of signalling pathways by control of miR-24 expression

(2009) Mun Chun Chan et al.   EMBO JOURNAL

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

(2009) M. Xin et al.   GENES & DEVELOPMENT

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

(2009) Kimberly R. Cordes et al.   NATURE

Angiotensin II-Induced Osteopontin Expression in Vascular Smooth Muscle Cells Involves Gq/11, Ras, ERK, Src and Ets-1

(2008) Keiko ABE et al.   HYPERTENSION RESEARCH

Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype

(2008) Brandi N. Davis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myocardin inhibits cellular proliferation by inhibiting NF- B(p65)-dependent cell cycle progression

(2008) R.-h. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

(2008) T. A. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA