DCLK1 promotes epithelial-mesenchymal transition via the PI3K/Akt/NF-κB pathway in colorectal cancer

miR-377-3p drives malignancy characteristics via upregulating GSK-3β expression and activating NF-κB pathway in hCRC cells

(2017) Wei-Ying Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells

(2017) Parthasarathy Chandrakesan et al.   Molecular Cancer

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Methylation of the DCLK1 promoter region in circulating free DNA and its prognostic value in lung cancer patients

(2015) T. Powrózek et al.   Clinical & Translational Oncology

Tetramethylpyrazine induces SH-SY5Y cell differentiation toward the neuronal phenotype through activation of the PI3K/Akt/Sp1/TopoIIβ pathway

(2015) Yong-xin Yan et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

miR-212/132 downregulates SMAD2 expression to suppress the G1/S phase transition of the cell cycle and the epithelial to mesenchymal transition in cervical cancer cells

(2015) Jian-Li Zhao et al.   IUBMB LIFE

Epithelial–mesenchymal transition in colorectal cancer metastasis: A system review

(2015) Hui Cao et al.   PATHOLOGY RESEARCH AND PRACTICE

Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism

(2015) Sripathi M. Sureban et al.   Oncotarget

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1

(2015) Chiara Giorgi et al.   Oncotarget

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

(2015) Nathaniel Weygant et al.   Oncotarget

Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications

(2015) Malaney R. O’Connell et al.   Scientific Reports

MiR-124 represses vasculogenic mimicry and cell motility by targeting amotL1 in cervical cancer cells

(2014) Hai-Ying Wan et al.   CANCER LETTERS

The recently suggested intestinal cancer stem cell markerDCLK1is an epigenetic biomarker for colorectal cancer

(2014) Hege Marie Vedeld et al.   Epigenetics

The novel colorectal cancer biomarkersCDO1, ZSCAN18andZNF331are frequently methylated across gastrointestinal cancers

(2014) Hege Marie Vedeld et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of BRMS1 Promotes a Mesenchymal Phenotype through NF-κB-Dependent Regulation ofTwist1

(2014) Yuan Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer

(2013) Jennifer M. Bailey et al.   GASTROENTEROLOGY

Colorectal cancer

(2013) Hermann Brenner et al.   LANCET

DCLK1 Regulates Pluripotency and Angiogenic Factors via microRNA-Dependent Mechanisms in Pancreatic Cancer

(2013) Sripathi M. Sureban et al.   PLoS One

Sp1 is involved in regulation of cystathionine γ-lyase gene expression and biological function by PI3K/Akt pathway in human hepatocellular carcinoma cell lines

(2012) Peng Yin et al.   CELLULAR SIGNALLING

Novel target genes and a valid biomarker panel identified for cholangiocarcinoma

(2012) Kim Andresen et al.   Epigenetics

Dclk1 distinguishes between tumor and normal stem cells in the intestine

(2012) Yuki Nakanishi et al.   NATURE GENETICS

CD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triple-negative breast cancer

(2012) T J Liu et al.   ONCOGENE

DCAMKL-1 Regulates Epithelial-Mesenchymal Transition in Human Pancreatic Cells through a miR-200a-Dependent Mechanism

(2011) S. M. Sureban et al.   CANCER RESEARCH

Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism

(2011) Sripathi M Sureban et al.   JOURNAL OF NANOBIOTECHNOLOGY

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The morphological and molecular features of the epithelial-to-mesenchymal transition

(2009) Gema Moreno-Bueno et al.   Nature Protocols

NF-κB and epithelial to mesenchymal transition of cancer

(2008) Chengyin Min et al.   JOURNAL OF CELLULAR BIOCHEMISTRY