TREM2 Ameliorates Neuronal Tau Pathology Through Suppression of Microglial Inflammatory Response
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Title
TREM2 Ameliorates Neuronal Tau Pathology Through Suppression of Microglial Inflammatory Response
Authors
Keywords
Alzheimer’s disease, TREM2, tau pathology, microglia, inflammation, tau kinase
Journal
INFLAMMATION
Volume 41, Issue 3, Pages 811-823
Publisher
Springer Nature
Online
2018-01-23
DOI
10.1007/s10753-018-0735-5
References
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Related references
Note: Only part of the references are listed.- Tau Aggregation and Toxicity in Tauopathic Neurodegenerative Diseases
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- (2016) Mansi R. Khanna et al. Alzheimers & Dementia
- TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice
- (2016) Teng Jiang et al. NEUROPHARMACOLOGY
- Activated human microglia stimulate neuroblastoma cells to upregulate production of beta amyloid protein and tau: implications for Alzheimer's disease pathogenesis
- (2015) Moonhee Lee et al. NEUROBIOLOGY OF AGING
- Silencing of TREM2 exacerbates tau pathology, neurodegenerative changes, and spatial learning deficits in P301S tau transgenic mice
- (2015) Teng Jiang et al. NEUROBIOLOGY OF AGING
- TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices
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- TYROBP in Alzheimer’s Disease
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- Temsirolimus attenuates tauopathy in vitro and in vivo by targeting tau hyperphosphorylation and autophagic clearance
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- Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease
- (2014) Teng Jiang et al. NEUROPSYCHOPHARMACOLOGY
- TREM2 in Alzheimer’s disease
- (2013) Teng Jiang et al. MOLECULAR NEUROBIOLOGY
- Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice
- (2013) Teng Jiang et al. NEUROBIOLOGY OF AGING
- Variant TREM2 as Risk Factor for Alzheimer's Disease
- (2012) Harald Neumann et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
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- LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
- (2010) Daniel C Lee et al. Journal of Neuroinflammation
- A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia
- (2009) Christine L. Hsieh et al. JOURNAL OF NEUROCHEMISTRY
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