Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice

Correlation between Gene Expression and Osteoarthritis Progression in Human

(2016) Leilei Zhong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-105/Runx2 axis mediates FGF2-induced ADAMTS expression in osteoarthritis cartilage

(2016) Quanbo Ji et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

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(2016)   JOURNAL OF CELLULAR BIOCHEMISTRY

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(2016)   JOURNAL OF ORTHOPAEDIC RESEARCH

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(2016)   PATHOLOGY INTERNATIONAL

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

(2014) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of the Transforming Growth Factor β Receptor Type II Gene in Articular Chondrocytes Leads to a Progressive Osteoarthritis-like Phenotype in Mice

(2013) Jie Shen et al.   ARTHRITIS AND RHEUMATISM

An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice

(2013) Takeshi Takarada et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

(2013) Gehua Zhen et al.   NATURE MEDICINE

Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis

(2013) Akihiko Hasegawa et al.   ARTHRITIS RESEARCH & THERAPY

MMP13 is a critical target gene during the progression of osteoarthritis

(2013) Meina Wang et al.   ARTHRITIS RESEARCH & THERAPY

Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue

(2012) Meina Wang et al.   ARTHRITIS AND RHEUMATISM

Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis

(2012) Carol G. Chen et al.   ARTHRITIS AND RHEUMATISM

Osterix Regulates Calcification and Degradation of Chondrogenic Matrices through Matrix Metalloproteinase 13 (MMP13) Expression in Association with Transcription Factor Runx2 during Endochondral Ossification

(2012) Riko Nishimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

(2011) Meina Wang et al.   Annals of the New York Academy of Sciences

Osteochondral alterations in osteoarthritis

(2011) Sunita Suri et al.   BONE

C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes

(2011) Makoto Hirata et al.   HUMAN MOLECULAR GENETICS

Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer

(2011) Feifei Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development

(2011) B. Shu et al.   JOURNAL OF CELL SCIENCE

Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling

(2010) A. Kadri et al.   ANNALS OF THE RHEUMATIC DISEASES

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells

(2010) T. Tetsunaga et al.   OSTEOARTHRITIS AND CARTILAGE

Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage

(2009) Stephen P. Henry et al.   GENESIS

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols