Single-cell analysis reveals cancer stem cell heterogeneity in hepatocellular carcinoma

Annual Report to the Nation on the Status of Cancer, 1975–2014, Featuring Survival

(2017) Ahmedin Jemal et al.   JNCI-Journal of the National Cancer Institute

Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

(2017) Huipeng Li et al.   NATURE GENETICS

Normalizing single-cell RNA sequencing data: challenges and opportunities

(2017) Catalina A Vallejos et al.   NATURE METHODS

Tracking the Evolution of Non–Small-Cell Lung Cancer

(2017) Mariam Jamal-Hanjani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Annual Report to the Nation on the Status of Cancer, 1975–2014, Featuring Survival

(2017) Ahmedin Jemal et al.   JNCI-Journal of the National Cancer Institute

GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis

(2016) Qing-Hai Ye et al.   CANCER CELL

Single-cell triple omics sequencing reveals genetic, epigenetic and transcriptomic heterogeneity in hepatocellular carcinomas

(2016) Yu Hou et al.   CELL RESEARCH

Tracing haematopoietic stem cell formation at single-cell resolution

(2016) Fan Zhou et al.   NATURE

Single-cell genome sequencing: current state of the science

(2016) Charles Gawad et al.   NATURE REVIEWS GENETICS

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma

(2016) Takayuki Kawai et al.   Scientific Reports

A comparison of human and mouse gene co-expression networks reveals conservation and divergence at the tissue, pathway and disease levels

(2015) Gianni Monaco et al.   BMC EVOLUTIONARY BIOLOGY

Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells

(2015) Florian Mertes et al.   BMC GENOMICS

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

(2015) Nicola K. Wilson et al.   Cell Stem Cell

Keratin 19, a Cancer Stem Cell Marker in Human Hepatocellular Carcinoma

(2015) T. Kawai et al.   CLINICAL CANCER RESEARCH

Computational and analytical challenges in single-cell transcriptomics

(2015) Oliver Stegle et al.   NATURE REVIEWS GENETICS

Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM+ AFP+ hepatocellular carcinoma

(2015) X Zhao et al.   ONCOGENE

Erratum: Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+ liver cancer initiating cells by suppressing negative regulators of β-catenin signaling

(2015) Z-J Lei et al.   ONCOGENE

Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution

(2015) Shaoping Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of CD47-mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma

(2014) Terence Kin-Wah Lee et al.   HEPATOLOGY

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

Single-cell technologies for monitoring immune systems

(2014) Pratip K Chattopadhyay et al.   NATURE IMMUNOLOGY

HCC therapies—lessons learned

(2014) Marcus-Alexander Wörns et al.   Nature Reviews Gastroenterology & Hepatology

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Expression of Intercellular Adhesion Molecule 1 by Hepatocellular Carcinoma Stem Cells and Circulating Tumor Cells

(2013) Shupeng Liu et al.   GASTROENTEROLOGY

Cancer stem cells in the development of liver cancer

(2013) Taro Yamashita et al.   JOURNAL OF CLINICAL INVESTIGATION

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Understanding cancer stem cell heterogeneity and plasticity

(2012) Dean G Tang   CELL RESEARCH

Discrete nature of EpCAM+and CD90+cancer stem cells in human hepatocellular carcinoma

(2012) Taro Yamashita et al.   HEPATOLOGY

DLK1 as a Potential Target against Cancer Stem/Progenitor Cells of Hepatocellular Carcinoma

(2012) X. Xu et al.   MOLECULAR CANCER THERAPEUTICS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation

(2011) Terence Kin Wah Lee et al.   Cell Stem Cell

CD13 is a therapeutic target in human liver cancer stem cells

(2010) Naotsugu Haraguchi et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma

(2009) Y. Hoshida et al.   CANCER RESEARCH

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY