Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells

(2014) Noushin Dianat et al.   HEPATOLOGY

Emerging roles of Notch signaling in liver disease

(2014) Fabian Geisler et al.   HEPATOLOGY

Cystic Fibrosis Related Liver Disease—Another Black Box in Hepatology

(2014) Katharina Staufer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Production of hepatocyte-like cells from human pluripotent stem cells

(2013) Nicholas R F Hannan et al.   Nature Protocols

Pathophysiology of cystic fibrosis and drugs used in associated digestive tract diseases

(2013) Adriana Haack   WORLD JOURNAL OF GASTROENTEROLOGY

Generation of Multipotent Foregut Stem Cells from Human Pluripotent Stem Cells

(2013) Nicholas R.F. Hannan et al.   Stem Cell Reports

The promise of induced pluripotent stem cells in research and therapy

(2012) Daisy A. Robinton et al.   NATURE

Systematic review: the pathophysiology and management of polycystic liver disease

(2011) F. Temmerman et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Alagille syndrome: pathogenesis, diagnosis and management

(2011) Peter D Turnpenny et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis

(2011) Peggy Raynaud et al.   HEPATOLOGY

Culture of porcine hepatocytes or bile duct epithelial cells by inductive serum-free media

(2011) Thomas J. Caperna et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Calcium-Modulated Chloride Pathways Contribute to Chloride Flux in Murine Cystic Fibrosis-Affected Macrophages

(2011) Ambika Shenoy et al.   PEDIATRIC RESEARCH

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

(2011) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for theF508del-CFTRmutation

(2011) J P Clancy et al.   THORAX

Will we ever model PSC? – “It's hard to be a PSC model!”

(2011) Marion J. Pollheimer et al.   Clinics and Research in Hepatology and Gastroenterology

Reducing Polycystic Liver Volume in ADPKD: Effects of Somatostatin Analogue Octreotide

(2010) A. Caroli et al.   Clinical Journal of the American Society of Nephrology

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

(2010) S. Tamir Rashid et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch signaling controls liver development by regulating biliary differentiation

(2009) Y. Zong et al.   DEVELOPMENT

Notch signaling is required for lateral induction of Jagged1 during FGF-induced lens fiber differentiation

(2009) Senthil S. Saravanamuthu et al.   DEVELOPMENTAL BIOLOGY

Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9

(2009) Aline Antoniou et al.   GASTROENTEROLOGY

Derivation and Characterization of Hepatic Progenitor Cells from Human Embryonic Stem Cells

(2009) Dongxin Zhao et al.   PLoS One

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

FGF signaling segregates biliary cell-lineage from chick hepatoblasts cooperatively with BMP4 and ECM components in vitro

(2008) Masaaki Yanai et al.   DEVELOPMENTAL DYNAMICS