Transition-metal-free C–N and C–C formation: synthesis of benzo[4,5]imidazo[1,2-a]pyridines and 2-pyridones from ynones

Atom-Economic Synthesis of 4-Pyrones from Diynones and Water

(2017) Yan-Li Xu et al.   MOLECULES

Iron-Catalyzed Intermolecular Hydrothiolation of Internal Alkynes with Thiosalicylic Acids, and Sequential Intramolecular Cyclization Reaction

(2017) Taro Sonehara et al.   ORGANIC LETTERS

Phosphine–Borane Frustrated Lewis Pairs Derived from a 1,1′-Disubstituted Ferrocene Scaffold: Synthesis and Hydrogenation Catalysis

(2017) Zhongbao Jian et al.   ORGANOMETALLICS

Transition Metal-Free Synthesis of 3-Alkynylpyrrole-2-carboxylatesviaMichael Addition/Intramolecular Cyclodehydration

(2016) Qing-hu Teng et al.   ADVANCED SYNTHESIS & CATALYSIS

Gold(I)/ChiralN,N′-Dioxide-Nickel(II) Relay Catalysis for Asymmetric Tandem Intermolecular Hydroalkoxylation/Claisen Rearrangement

(2016) Jun Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A photoredox catalyzed radical–radical coupling reaction: facile access to multi-substituted nitrogen heterocycles

(2016) Weipeng Li et al.   CHEMICAL COMMUNICATIONS

Direct synthesis of 2,5-diformylfuran from fructose with graphene oxide as a bifunctional and metal-free catalyst

(2016) Guangqiang Lv et al.   GREEN CHEMISTRY

Transition-metal-free regioselective synthesis of alkylboronates from arylacetylenes and vinyl arenes

(2016) Kai Yang et al.   GREEN CHEMISTRY

Metal-Free Radical Oxidative Annulation of Ynones with Alkanes To Access Indenones

(2016) Changduo Pan et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Spiro-lactams and Polysubstituted Pyrroles via Ceric Ammonium Nitrate-Mediated Oxidative Cyclization of N-Furan-2-ylmethyl-β-Enaminones

(2016) Hui Peng et al.   JOURNAL OF ORGANIC CHEMISTRY

Iodine/Copper Iodide-Mediated C–H Functionalization: Synthesis of Imidazo[1,2-a]pyridines and Indoles from N-Aryl Enamines

(2016) Jing Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Transition-Metal-Free Synthesis of Tertiary Aminocyclopropanes

(2016) Patrick Cyr et al.   ORGANIC LETTERS

One-Pot Regiospecific Synthesis of Quinoxalines via a CH2-Extrusion Reaction

(2016) Jinhai Shen et al.   ORGANIC LETTERS

Preparation and Reactions of Indoleninyl Halides: Scaffolds for the Synthesis of Spirocyclic Indole Derivatives

(2016) John T. R. Liddon et al.   ORGANIC LETTERS

A Carbonylation Approach Toward Activation of Csp2-H and Csp3-H Bonds: Cu-Catalyzed Regioselective Cross Coupling of Imidazo[1,2-a]pyridines with Methyl Hetarenes

(2016) Sai Lei et al.   ORGANIC LETTERS

TEMPO-catalyzed synthesis of 5-substituted isoxazoles from propargylic ketones and TMSN3

(2016) Yan He et al.   RSC Advances

Transition-metal-free synthesis of oxazoles: valuable structural fragments in drug discovery

(2016) Aliya Ibrar et al.   RSC Advances

Regioselective Oxidative Homocoupling Reaction: An Efficient Copper-Catalyzed Synthesis of Biimidazo[1,2-a]pyridines

(2015) Sai Lei et al.   ADVANCED SYNTHESIS & CATALYSIS

Regioselective Copper-Catalyzed Oxidative Cross-Coupling of Imidazo[1,2-a]pyridines with Methyl Ketones: An Efficient Route for Synthesis of 1,2-Diketones

(2015) Sai Lei et al.   ADVANCED SYNTHESIS & CATALYSIS

Cu-Catalyzed selective C3-formylation of imidazo[1,2-a]pyridine C–H bonds with DMSO using molecular oxygen

(2015) Hua Cao et al.   CHEMICAL COMMUNICATIONS

Water-soluble oxoglaucine-Y(iii), Dy(iii) complexes: in vitro and in vivo anticancer activities by triggering DNA damage, leading to S phase arrest and apoptosis

(2015) Jian-Hua Wei et al.   DALTON TRANSACTIONS

Regioselective Copper-Catalyzed Dicarbonylation of Imidazo[1,2-a]pyridines with N,N-Disubstituted Acetamide or Acetone: An Approach to 1,2-Diketones Using Molecular Oxygen

(2015) Changcheng Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Inter- and Intramolecular C–N Bond Formation: Synthesis of Benzimidazole-Fused Heterocycles

(2015) Sk. Rasheed et al.   JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Formal Dehydrative [4 + 2] Cycloaddition of Enamides and Alkynes for the Synthesis of Highly Substituted Pyridines: Reaction Development and Mechanistic Study

(2015) Jicheng Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver(I)-Catalyzed Dearomatization of Alkyne-Tethered Indoles: Divergent Synthesis of Spirocyclic Indolenines and Carbazoles

(2015) Michael J. James et al.   ORGANIC LETTERS

Indium-Catalyzed [2 + 2] Cycloaddition of Allylsilanes to Internal Alkynones

(2015) Kazuhiro Okamoto et al.   ORGANIC LETTERS

Transition-Metal-Free Multicomponent Benzannulation Reactions for the Construction of Polysubstituted Benzene Derivatives

(2015) Wen-Ming Shu et al.   ORGANIC LETTERS

Base-Promoted N-Pyridylation of Heteroarenes Using N-Propargyl Enaminones as Equivalents of Pyridine Scaffolds

(2015) Guolin Cheng et al.   ORGANIC LETTERS

Facile synthesis of aryl-substituted pyridines via Suzuki–Miyaura approach

(2015) Eda Karadeniz et al.   TETRAHEDRON

Facile synthesis of iodopyridines from N-propargylic β-enaminones via iodine-mediated electrophilic cyclization

(2015) Sedef Karabiyikoglu et al.   TETRAHEDRON

Rh-catalyzed decarbonylation of conjugated ynones via carbon–alkyne bond activation: reaction scope and mechanistic exploration via DFT calculations

(2015) Alpay Dermenci et al.   Chemical Science

Gold-catalyzed formal [4π + 2π]-cycloadditions of propiolate derivatives with unactivated nitriles

(2015) Somnath Narayan Karad et al.   Chemical Science

A copper-catalyzed multi-component reaction accessing fused imidazo-heterocycles via C–H functionalization

(2015) G. Santosh Kumar et al.   RSC Advances

Functionalised MnVI-nanoparticles: an advanced high-valent magnetic catalyst

(2015) Saikat Khamarui et al.   Scientific Reports

Copper-Catalyzed Oxidative C−H Amination: Synthesis of Imidazo[1,2-a]-N-Heterocycles from N-Heteroaryl Enaminones

(2015) K. Ranjith Reddy et al.   Asian Journal of Organic Chemistry

Metal-Free Annulation of Arenes with 2-Aminopyridine Derivatives: The Methyl Group as a Traceless Non-Chelating Directing Group

(2014) Srimanta Manna et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective Transfer Hydrogenation of α,β-Unsaturated Carbonyls Using Palladium Immobilized Ionic Liquid Catalyst

(2014) Nilesh M. Patil et al.   CATALYSIS LETTERS

Transition-Metal-Free Coupling Reactions

(2014) Chang-Liang Sun et al.   CHEMICAL REVIEWS

Hypervalent Iodine(III) Promoted Direct Synthesis of Imidazo[1,2-a]pyrimidines

(2014) Guangyin Qian et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Aerobic Oxidation of Biomass-Derived 5-(Hydroxymethyl)furfural into 2,5-Diformylfuran Catalyzed by the Trimetallic Mixed Oxide (Co–Ce–Ru)

(2014) Yimei Wang et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Two-Chamber Hydrogen Generation and Application: Access to Pressurized Deuterium Gas

(2014) Amalie Modvig et al.   JOURNAL OF ORGANIC CHEMISTRY

Transition Metal-Mediated C═O and C═C Bond-Forming Reactions: A Regioselective Strategy for the Synthesis of Imidazo[1,2-a]pyridines and Imidazo[1,2-a]pyrazines

(2014) Hua Cao et al.   JOURNAL OF ORGANIC CHEMISTRY

Gold-Catalyzed 1,3-Transposition of Ynones

(2014) Roohollah Kazem Shiroodi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TMIO-PyrImid Hybrids are Profluorescent, Site-Directed Spin Labels for Nucleic Acids

(2014) Benjamin A. Chalmers et al.   ORGANIC LETTERS

An efficient ligand free chemoselective transfer hydrogenation of olefinic bonds by palladium nanoparticles in an aqueous reaction medium

(2014) Dattatraya B. Bagal et al.   RSC Advances

Hypervalent iodine(iii) catalyzed oxidative C–N bond formation in water: synthesis of benzimidazole-fused heterocycles

(2014) D. Nageswar Rao et al.   RSC Advances

“One pot” regiospecific synthesis of polysubstituted pyrroles from benzylamines and ynones under metal free conditions

(2013) Jinhai Shen et al.   CHEMICAL COMMUNICATIONS

C–H cycloamination of N-aryl-2-aminopyridines and N-arylamidines catalyzed by an in situ generated hypervalent iodine(iii) reagent

(2013) Yimiao He et al.   CHEMICAL COMMUNICATIONS

Rhodium(iii)-catalyzed vinylic sp2 C–H bond functionalization: efficient synthesis of pyrido[1,2-α]benzimidazoles and imidazo[1,2-α]pyridines

(2013) Lin Dong et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Metal-Free Tandem Demethylenation/C(sp2)–H Cycloamination Process of N-Benzyl-2-aminopyridines via C–C and C–N Bond Cleavage

(2013) Dongdong Liang et al.   ORGANIC LETTERS

Nucleophilic Addition of Benzimidazoles to Alkynyl Bromides/Palladium-Catalyzed Intramolecular C–H Vinylation: Synthesis of Benzo[4,5]imidazo[2,1-a]isoquinolines

(2012) Jinsong Peng et al.   JOURNAL OF ORGANIC CHEMISTRY

Transition-Metal-Free Electrophilic Amination of Arylboroxines

(2012) Qing Xiao et al.   ORGANIC LETTERS

Transition-Metal-Free Intramolecular N-Arylations

(2012) Isabelle Thomé et al.   ORGANIC LETTERS

Copper(II)/Iron(III) Co-catalyzed Intermolecular Diamination of Alkynes: Facile Synthesis of Imidazopyridines

(2012) Jing Zeng et al.   ORGANIC LETTERS

Domino reactions of 1-(2-alkoxyaryl)-3-akylprop-2-yn-1-ones with sodium sulfide leading to thiochromen-4-one derivatives

(2012) Xiaobo Yang et al.   RSC Advances

Catalytic Syntheses of N-Heterocyclic Ynones and Ynediones by In Situ Activation of Carboxylic Acids with Oxalyl Chloride

(2011) Christina Boersch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel imidazo[4,5-b]pyridine and triaza-benzo[c]fluorene derivatives: Synthesis, antiproliferative activity and DNA binding studies

(2011) Marijana Hranjec et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Pyrido[1,2-a]benzimidazoles through a Copper-Catalyzed Cascade C-N Coupling Process

(2011) Zhiqing Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

An efficient and heterogeneous recyclable palladium catalyst for chemoselective conjugate reduction of α,β-unsaturated carbonyls in aqueous medium

(2011) Dattatraya B. Bagal et al.   GREEN CHEMISTRY

A supported palladium nanocatalyst for copper free acyl Sonogashira reactions: One-pot multicomponent synthesis of N-containing heterocycles

(2011) Subhankar Santra et al.   GREEN CHEMISTRY

Antimalarial Pyrido[1,2-a]benzimidazoles

(2011) Albert J. Ndakala et al.   JOURNAL OF MEDICINAL CHEMISTRY

CuI-catalyzed tandem carbomagnesiation/carbonyl addition of Grignard reagents with acetylenic ketones: Convenient access to tetrasubstituted allylic alcohols

(2011) Meihua Xie et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Novel pyridobenzimidazole derivatives exhibiting antifungal activity by the inhibition of β-1,6-glucan synthesis

(2010) Hiroshi Takeshita et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Formamidines - Versatile Ligands for Zinc-Catalyzed Hydrosilylation and Iron-Catalyzed Epoxidation Reactions

(2010) Stephan Enthaler et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Direct Intramolecular C−H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles fromN-Aryl-2-aminopyridines

(2010) Honggen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed CC Bond Formation through CH Functionalization: Synthesis of Multisubstituted Indoles fromN-Aryl Enaminones

(2009) Roberta Bernini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Titanocene-Catalyzed Conjugate Reduction of α,β-Unsaturated Carbonyl Derivatives

(2009) Andrew D. Kosal et al.   ORGANIC LETTERS

Synthesis of Pyrroles by Gold(I)-Catalyzed Amino−Claisen Rearrangement ofN-Propargyl Enaminone Derivatives

(2009) Akio Saito et al.   ORGANIC LETTERS

Novel Palladium-on-Carbon/Diphenyl Sulfide Complex for Chemoselective Hydrogenation: Preparation, Characterization, and Application

(2008) Akinori Mori et al.   ADVANCED SYNTHESIS & CATALYSIS

Facile and Convenient Method of Deuterium Gas Generation Using a Pd/C-Catalyzed H2–D2 Exchange Reaction and Its Application to Synthesis of Deuterium-Labeled Compounds

(2008) Takanori Kurita et al.   CHEMISTRY-A EUROPEAN JOURNAL

Novel Amidino-Substituted Thienyl- and Furylvinylbenzimidazole: Derivatives and Their Photochemical Conversion into Corresponding Diazacyclopenta[c]fluorenes. Synthesis, Interactions with DNA and RNA, and Antitumor Evaluation. 4

(2008) Marijana Hranjec et al.   JOURNAL OF MEDICINAL CHEMISTRY

Differential antiproliferative mechanisms of novel derivative of benzimidazo[1,2- ]quinoline in colon cancer cells depending on their p53 status

(2008) M. Sedic et al.   MOLECULAR CANCER THERAPEUTICS

N-Propargylic β-Enaminones: Common Intermediates for the Synthesis of Polysubstituted Pyrroles and Pyridines

(2008) Sandro Cacchi et al.   ORGANIC LETTERS