Journal
ORGANIC LETTERS
Volume 18, Issue 24, Pages 6448-6451Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b03345
Keywords
-
Categories
Ask authors/readers for more resources
A transition-metal-free methodology for the construction of pharmaceutically relevant tertiary aminocyclopropanes is reported. Hydrazonamides, safe and stable carbene precursors, undergo smooth cyclopropanation with vinyl arenes in the presence of a base. The reaction proceeds with stereoselectivity to favor the Z isomer and provides facile access to a variety of substitution patterns through variation of the coupling partners.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available