L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis

Heritable L1 retrotransposition in the mouse primordial germline and early embryo

(2017) Sandra R. Richardson et al.   GENOME RESEARCH

The Mobile Element Locator Tool (MELT): population-scale mobile element discovery and biology

(2017) Eugene J. Gardner et al.   GENOME RESEARCH

Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer

(2017) Zuojian Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

L1 Mosaicism in Mammals: Extent, Effects, and Evolution

(2017) Geoffrey J. Faulkner et al.   TRENDS IN GENETICS

The Role of Somatic L1 Retrotransposition in Human Cancers

(2017) Emma Scott et al.   Viruses-Basel

Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

(2017) Apinya Jusakul et al.   Cancer Discovery

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH -Mutant Molecular Profiles

(2017) Farshad Farshidfar et al.   Cell Reports

Epidemiology and risk factors: intrahepatic cholangiocarcinoma

(2017) Amar Gupta et al.   HEPATOBILIARY SURGERY AND NUTRITION

Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors

(2016) T. R. Kress et al.   CANCER RESEARCH

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer

(2016) Emma C. Scott et al.   GENOME RESEARCH

Mutual epithelium-macrophage dependency in liver carcinogenesis mediated by ST18

(2016) Micol Ravà et al.   HEPATOLOGY

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma

(2016) Tara T. Doucet-O'Hare et al.   HUMAN MUTATION

International trends in liver cancer incidence, overall and by histologic subtype, 1978-2007

(2016) Jessica L. Petrick et al.   INTERNATIONAL JOURNAL OF CANCER

L1-associated genomic regions are deleted in somatic cells of the healthy human brain

(2016) Jennifer A Erwin et al.   NATURE NEUROSCIENCE

The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning

(2016) Jennifer L. Hazen et al.   NEURON

The pathways of genetic transformation in cholangiocarcinogenesis

(2016) Francesco M. Serafini et al.   Cancer Genetics

Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci

(2016) Claude Philippe et al.   eLife

Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme

(2016) Patricia E. Carreira et al.   Mobile DNA

Somatic retrotransposition is infrequent in glioblastomas

(2016) Pragathi Achanta et al.   Mobile DNA

Restricting retrotransposons: a review

(2016) John L. Goodier   Mobile DNA

Roles for retrotransposon insertions in human disease

(2016) Dustin C. Hancks et al.   Mobile DNA

Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications

(2015) Xiaoyu Chen et al.   BIOINFORMATICS

Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis

(2015) Anna L. Paterson et al.   BMC GENOMICS

Ubiquitous L1 Mosaicism in Hippocampal Neurons

(2015) Kyle R. Upton et al.   CELL

p53 genes function to restrain mobile elements

(2015) Annika Wylie et al.   GENES & DEVELOPMENT

CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors

(2015) Kosuke Hashimoto et al.   GENOME RESEARCH

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution

(2015) Adam D. Ewing et al.   GENOME RESEARCH

Genomic spectra of biliary tract cancer

(2015) Hiromi Nakamura et al.   NATURE GENETICS

Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma

(2015) Nemanja Rodić et al.   NATURE MEDICINE

Role of Merlin/NF2 inactivation in tumor biology

(2015) A M Petrilli et al.   ONCOGENE

LINE-1 expression and retrotransposition in Barrett’s esophagus and esophageal carcinoma

(2015) Tara T. Doucet-O'Hare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer

(2015) Juan Tan et al.   Scientific Reports

Transposable element detection from whole genome sequence data

(2015) Adam D. Ewing   Mobile DNA

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer

(2015) Esa Pitkänen et al.   Oncotarget

L1 Retrotransposons and Somatic Mosaicism in the Brain

(2014) Sandra R. Richardson et al.   Annual Review of Genetics

Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer

(2014) Rafael Guerrero-Preston et al.   Epigenetics

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing

(2014) E. Helman et al.   GENOME RESEARCH

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Neuronal cell type–specific alternative splicing is regulated by the KH domain protein SLM1

(2014) Takatoshi Iijima et al.   JOURNAL OF CELL BIOLOGY

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

(2014) J. M. C. Tubio et al.   SCIENCE

Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma

(2013) Ruchi Shukla et al.   CELL

L1 retrotransposons, cancer stem cells and oncogenesis

(2013) Patricia E. Carreira et al.   FEBS Journal

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

(2013) Sumera Rizvi et al.   GASTROENTEROLOGY

Transduction-Specific ATLAS Reveals a Cohort of Highly Active L1 Retrotransposons in Human Populations

(2013) Catriona M. Macfarlane et al.   HUMAN MUTATION

LINE-1 Retrotransposable Element DNA Accumulates in HIV-1-Infected Cells

(2013) R. B. Jones et al.   JOURNAL OF VIROLOGY

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers

(2013) Waraporn Chan-on et al.   NATURE GENETICS

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

(2013) Yuchen Jiao et al.   NATURE GENETICS

Revisiting the evolution of mouse LINE-1 in the genomic era

(2013) Akash Sookdeo et al.   Mobile DNA

Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain

(2012) Gilad D. Evrony et al.   CELL

Extensive somatic L1 retrotransposition in colorectal tumors

(2012) S. Solyom et al.   GENOME RESEARCH

Landscape of Somatic Retrotransposition in Human Cancers

(2012) E. Lee et al.   SCIENCE

ARID1A Mutations in Cancer: Another Epigenetic Tumor Suppressor?

(2012) Jennifer N. Wu et al.   Cancer Discovery

The fine-scale architecture of structural variants in 17 mouse genomes

(2012) Binnaz Yalcin et al.   GENOME BIOLOGY

The genomic landscape shaped by selection on transposable elements across 18 mouse strains

(2012) Christoffer Nellåker et al.   GENOME BIOLOGY

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

Somatic retrotransposition alters the genetic landscape of the human brain

(2011) J. Kenneth Baillie et al.   NATURE

Mouse genomic variation and its effect on phenotypes and gene regulation

(2011) Thomas M. Keane et al.   NATURE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells

(2011) N. G. Coufal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repetitive Elements May Comprise Over Two-Thirds of the Human Genome

(2011) A. P. Jason de Koning et al.   PLoS Genetics

Natural Mutagenesis of Human Genomes by Endogenous Retrotransposons

(2010) Rebecca C. Iskow et al.   CELL

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

(2010) Johanna C. Scheuermann et al.   NATURE

L1 retrotransposition in neurons is modulated by MeCP2

(2010) Alysson R. Muotri et al.   NATURE

Proliferative and Nonproliferative Lesions of the Rat and Mouse Hepatobiliary System

(2010) Bob Thoolen et al.   TOXICOLOGIC PATHOLOGY

L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism

(2009) H. Kano et al.   GENES & DEVELOPMENT

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Polybromo-1: The chromatin targeting subunit of the PBAF complex

(2008) Martin Thompson   BIOCHIMIE

Retrotransposons Revisited: The Restraint and Rehabilitation of Parasites

(2008) John L. Goodier et al.   CELL

The impact of multiple splice sites in human L1 elements

(2008) V.P. Belancio et al.   GENE

Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition

(2008) K. Akagi et al.   GENOME RESEARCH

A single amino acid substitution in ORF1 dramatically decreases L1 retrotransposition and provides insight into nucleic acid chaperone activity

(2008) S. L. Martin et al.   NUCLEIC ACIDS RESEARCH

QUMA: quantification tool for methylation analysis

(2008) Y. Kumaki et al.   NUCLEIC ACIDS RESEARCH