Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice

Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice

(2018) Stefan Just et al.   PLoS One

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

(2017) Nicolas Snaidero et al.   Cell Reports

Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase

(2016) René Fuertig et al.   BRAIN BEHAVIOR AND IMMUNITY

Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behavior and memory in mice

(2016) Federica Klaus et al.   BRAIN BEHAVIOR AND IMMUNITY

Distinct Hippocampal Pathways Mediate Dissociable Roles of Context in Memory Retrieval

(2016) Chun Xu et al.   CELL

Mouse psychosocial stress reduces motivation and cognitive function in operant reward tests: A model for reward pathology with effects of agomelatine

(2016) Giorgio Bergamini et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Heterogeneity in oligodendroglia: Is it relevant to mouse models and human disease?

(2016) Isis M. Ornelas et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Integrating neuroimmune systems in the neurobiology of depression

(2016) Eric S. Wohleb et al.   NATURE REVIEWS NEUROSCIENCE

Chronic psychosocial stress in mice leads to changes in brain functional connectivity and metabolite levels comparable to human depression

(2016) Joanes Grandjean et al.   NEUROIMAGE

The transcriptome of mouse central nervous system myelin

(2016) Sudhir Thakurela et al.   Scientific Reports

Association between chronic stress-induced structural abnormalities in Ranvier nodes and reduced oligodendrocyte activity in major depression

(2016) Shingo Miyata et al.   Scientific Reports

CD40-TNF activation in mice induces extended sickness behavior syndrome co-incident with but not dependent on activation of the kynurenine pathway

(2015) Flurin Cathomas et al.   BRAIN BEHAVIOR AND IMMUNITY

Exploring the origins of grey matter damage in multiple sclerosis

(2015) Massimiliano Calabrese et al.   NATURE REVIEWS NEUROSCIENCE

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

(2015) Janine Arloth et al.   NEURON

Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study

(2015) Daniel S. Tylee et al.   PSYCHONEUROENDOCRINOLOGY

Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABAB receptors associated with mood disorders

(2015) F Cathomas et al.   Translational Psychiatry

Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides

(2014) Susana G. Torres-Platas et al.   BRAIN BEHAVIOR AND IMMUNITY

Direct visualization of membrane architecture of myelinating cells in transgenic mice expressing membrane-anchored EGFP

(2014) Yaqi Deng et al.   GENESIS

Knockdown of Interleukin-1 Receptor Type-1 on Endothelial Cells Attenuated Stress-Induced Neuroinflammation and Prevented Anxiety-Like Behavior

(2014) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

Pathological circuit function underlying addiction and anxiety disorders

(2014) Andreas Lüthi et al.   NATURE NEUROSCIENCE

Amygdala Microcircuits Controlling Learned Fear

(2014) Sevil Duvarci et al.   NEURON

Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine function

(2014) Damiano Azzinnari et al.   NEUROPHARMACOLOGY

Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum

(2014) Haruko Miyazaki et al.   Nature Communications

The myelin membrane-associated enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase: on a highway to structure and function

(2014) Arne Raasakka et al.   Neuroscience Bulletin

CellMix: a comprehensive toolbox for gene expression deconvolution

(2013) R. Gaujoux et al.   BIOINFORMATICS

Digital sorting of complex tissues for cell type-specific gene expression profiles

(2013) Yi Zhong et al.   BMC BIOINFORMATICS

Toward the future of psychiatric diagnosis: the seven pillars of RDoC

(2013) Bruce N Cuthbert et al.   BMC Medicine

The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination

(2013) Rashad Hussain et al.   BRAIN

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

(2013) Grazyna Rajkowska et al.   CURRENT DRUG TARGETS

Neuroinflammation in white matter tracts ofCnp1mutant mice amplified by a minor brain injury

(2013) Georg L. Wieser et al.   GLIA

Translating the evidence for gene association with depression into mouse models of depression-relevant behaviour: Current limitations and future potential

(2013) Christopher R. Pryce et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Default Mode Network Activity and Connectivity in Psychopathology

(2012) Susan Whitfield-Gabrieli et al.   Annual Review of Clinical Psychology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A myelin gene causative of a catatonia-depression syndrome upon aging

(2012) Nora Hagemeyer et al.   EMBO Molecular Medicine

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Impaired adult myelination in the prefrontal cortex of socially isolated mice

(2012) Jia Liu et al.   NATURE NEUROSCIENCE

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Protecting White Matter From Stroke Injury

(2012) Carlos Matute et al.   STROKE

A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry

(2011) Laramie E. Duncan et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Serotonin Transporter Promoter Variant (5-HTTLPR), Stress, and Depression Meta-analysis Revisited

(2011) Katja Karg et al.   ARCHIVES OF GENERAL PSYCHIATRY

Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice

(2011) Dan Ehninger et al.   CELL AND TISSUE RESEARCH

Differential expression of genes encoding neuronal ion-channel subunits in major depression, bipolar disorder and schizophrenia: implications for pathophysiology

(2011) Bella Smolin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Establishing a learned-helplessness effect paradigm in C57BL/6 mice: Behavioural evidence for emotional, motivational and cognitive effects of aversive uncontrollability per se

(2011) Christopher R. Pryce et al.   NEUROPHARMACOLOGY

Dependent Stressful Life Events and Prior Depressive Episodes in the Prediction of Major Depression

(2010) Kenneth S. Kendler et al.   ARCHIVES OF GENERAL PSYCHIATRY

Cytoarchitectonic and chemoarchitectonic characterization of the prefrontal cortical areas in the mouse

(2010) H. J. J. M. Van De Werd et al.   Brain Structure & Function

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

A Molecular Signature of Depression in the Amygdala

(2009) Etienne Sibille et al.   AMERICAN JOURNAL OF PSYCHIATRY

Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia

(2009) A. Melani et al.   BRAIN

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Altered Negative BOLD Responses in the Default-Mode Network during Emotion Processing in Depressed Subjects

(2008) Simone Grimm et al.   NEUROPSYCHOPHARMACOLOGY

Immunological aspects in the neurobiology of suicide: Elevated microglial density in schizophrenia and depression is associated with suicide

(2006) Johann Steiner et al.   JOURNAL OF PSYCHIATRIC RESEARCH