A RhoA–YAP–c-Myc signaling axis promotes the development of polycystic kidney disease

Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ

(2016) Jing Yi et al.   HEPATOLOGY

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

Novel therapeutic approaches to autosomal dominant polycystic kidney disease

(2015) Wells B. LaRiviere et al.   Translational Research

Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization

(2015) Jakobus van Unen et al.   Scientific Reports

A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis

(2014) Q. Chen et al.   GENES & DEVELOPMENT

Multidrug Therapy for Polycystic Kidney Disease: A Review and Perspective

(2013) Gianluca Aguiari et al.   AMERICAN JOURNAL OF NEPHROLOGY

Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2

(2013) Feng Yin et al.   CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

(2013) D R Cook et al.   ONCOGENE

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development

(2013) Antoine Reginensi et al.   PLoS Genetics

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(2012) H. Abdollahpour et al.   BLOOD

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fluid transport and cystogenesis in autosomal dominant polycystic kidney disease

(2011) Sara Terryn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Polycystins, focal adhesions and extracellular matrix interactions

(2011) Iain A. Drummond   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival

(2011) N. T. Nehme et al.   BLOOD

Hippo pathway regulation by cell morphology and stress fibers

(2011) K.-I. Wada et al.   DEVELOPMENT

Altered Hippo signalling in polycystic kidney disease

(2011) Hester Happé et al.   JOURNAL OF PATHOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Polycystic kidney disease: Pathogenesis and potential therapies

(2010) Vinita Takiar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded

(2010) Jianzhong Yu et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

(2010) J. Cai et al.   GENES & DEVELOPMENT

The cell biology of polycystic kidney disease

(2010) Hannah C. Chapin et al.   JOURNAL OF CELL BIOLOGY

Advances in the pathogenesis and treatment of polycystic kidney disease

(2009) Vishal Patel et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

Mediator MED23 Links Insulin Signaling to the Adipogenesis Transcription Cascade

(2009) Wei Wang et al.   DEVELOPMENTAL CELL

Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks

(2009) Xuewen Song et al.   HUMAN MOLECULAR GENETICS

Reversible translocation of p115-RhoGEF by G12/13-coupled receptors

(2008) Bruno H. Meyer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

(2008) Milena Traykova-Brauch et al.   NATURE MEDICINE