An H7N1 Influenza Virus Vaccine Induces Broadly Reactive Antibody Responses against H7N9 in Humans

Emergence in China of human disease due to avian influenza A(H10N8) – Cause for concern?

(2014) Kelvin K.W. To et al.   JOURNAL OF INFECTION

Divergent H7 Immunogens Offer Protection from H7N9 Virus Challenge

(2014) F. Krammer et al.   JOURNAL OF VIROLOGY

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

Assessment of Human Immune Responses to H7 Avian Influenza Virus of Pandemic Potential: Results from a Placebo–Controlled, Randomized Double–Blind Phase I Study of Live Attenuated H7N3 Influenza Vaccine

(2014) Larisa Rudenko et al.   PLoS One

B Cell Response and Hemagglutinin Stalk-Reactive Antibody Production in Different Age Cohorts following 2009 H1N1 Influenza Virus Vaccination

(2013) Mark Y. Sangster et al.   Clinical and Vaccine Immunology

The emergence of H7N9 viruses: a chance to redefine correlates of protection for influenza virus vaccines

(2013) Florian Krammer et al.   Expert Review of Vaccines

H7N9: can H7N3 live-attenuated influenza vaccine be used at the early stage of the pandemic?

(2013) Larisa Rudenko et al.   Expert Review of Vaccines

H7N9 influenza viruses interact preferentially with  2,3-linked sialic acids and bind weakly to  2,6-linked sialic acids

(2013) I. Ramos et al.   JOURNAL OF GENERAL VIROLOGY

Cross-Reactive Influenza-Specific Antibody-Dependent Cellular Cytotoxicity Antibodies in the Absence of Neutralizing Antibodies

(2013) S. Jegaskanda et al.   JOURNAL OF IMMUNOLOGY

H3N2 Influenza Virus Infection Induces Broadly Reactive Hemagglutinin Stalk Antibodies in Humans and Mice

(2013) I. Margine et al.   JOURNAL OF VIROLOGY

Structural Analysis of the Hemagglutinin from the Recent 2013 H7N9 Influenza Virus

(2013) H. Yang et al.   JOURNAL OF VIROLOGY

Induction of Cross-Reactive Antibodies to Novel H7N9 Influenza Virus by Recombinant Newcastle Disease Virus Expressing a North American Lineage H7 Subtype Hemagglutinin

(2013) P. H. Goff et al.   JOURNAL OF VIROLOGY

Antibody-Dependent Cellular Cytotoxicity Is Associated with Control of Pandemic H1N1 Influenza Virus Infection of Macaques

(2013) S. Jegaskanda et al.   JOURNAL OF VIROLOGY

Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance

(2013) Yunwen Hu et al.   LANCET

Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice

(2013) Jessica A. Belser et al.   NATURE

Characterization of H7N9 influenza A viruses isolated from humans

(2013) Tokiko Watanabe et al.   NATURE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

(2013) H. Zhu et al.   SCIENCE

Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses

(2013) R. Xu et al.   SCIENCE

Neutralizing Antibodies Against Previously Encountered Influenza Virus Strains Increase over Time: A Longitudinal Analysis

(2013) M. S. Miller et al.   Science Translational Medicine

Vaccine-Induced Anti-HA2 Antibodies Promote Virus Fusion and Enhance Influenza Virus Respiratory Disease

(2013) S. Khurana et al.   Science Translational Medicine

One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge

(2013) Miriam Klausberger et al.   VACCINE

Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility

(2013) Rong Hai et al.   Nature Communications

Influenza virus hemagglutinin stalk-based antibodies and vaccines

(2013) Florian Krammer et al.   Current Opinion in Virology

Expression of Functional Recombinant Hemagglutinin and Neuraminidase Proteins from the Novel H7N9 Influenza Virus Using the Baculovirus Expression System

(2013) Irina Margine et al.   Jove-Journal of Visualized Experiments

Human infection with avian influenza A H6N1 virus: an epidemiological analysis

(2013) Sung-Hsi Wei et al.   Lancet Respiratory Medicine

Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice

(2012) F. Krammer et al.   JOURNAL OF VIROLOGY

Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

(2012) R. Hai et al.   JOURNAL OF VIROLOGY

A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates

(2012) Florian Krammer et al.   PLoS One

Residual Baculovirus in Insect Cell-Derived Influenza Virus-Like Particle Preparations Enhances Immunogenicity

(2012) Irina Margine et al.   PLoS One

A Randomized Clinical Trial of an Inactivated Avian Influenza A (H7N7) Vaccine

(2012) Robert B. Couch et al.   PLoS One

Evaluations for In Vitro Correlates of Immunogenicity of Inactivated Influenza A H5, H7 and H9 Vaccines in Humans

(2012) Robert B. Couch et al.   PLoS One

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

(2012) G.-M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

(2012) N. Pica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pandemic H1N1 Influenza Infection and Vaccination in Humans Induces Cross-Protective Antibodies that Target the Hemagglutinin Stem

(2012) C. A. Thomson et al.   Frontiers in Immunology

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Complement-Dependent Lysis of Influenza A Virus-Infected Cells by Broadly Cross-Reactive Human Monoclonal Antibodies

(2011) M. Terajima et al.   JOURNAL OF VIROLOGY

H3N2 Influenza Infection Elicits More Cross-Reactive and Less Clonally Expanded Anti-Hemagglutinin Antibodies Than Influenza Vaccination

(2011) M. Anthony Moody et al.   PLoS One

A Live Attenuated H7N7 Candidate Vaccine Virus Induces Neutralizing Antibody That Confers Protection from Challenge in Mice, Ferrets, and Monkeys

(2010) J.-Y. Min et al.   JOURNAL OF VIROLOGY

Trichoplusia ni cells (High FiveTM) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines

(2010) Florian Krammer et al.   MOLECULAR BIOTECHNOLOGY

A cell-based H7N1 split influenza virion vaccine confers protection in mouse and ferret challenge models

(2009) Rebecca J. Cox et al.   Influenza and Other Respiratory Viruses

A live attenuated H7N3 influenza virus vaccine is well tolerated and immunogenic in a Phase I trial in healthy adults

(2009) Kawsar R. Talaat et al.   VACCINE

A phase I clinical trial of a PER.C6® cell grown influenza H7 virus vaccine

(2009) Rebecca J. Cox et al.   VACCINE

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

(2008) Jens Wrammert et al.   NATURE

A live attenuated cold-adapted influenza A H7N3 virus vaccine provides protection against homologous and heterologous H7 viruses in mice and ferrets

(2008) Tomy Joseph et al.   VIROLOGY