Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

Expression of Zonulin, c-kit, and Glial Fibrillary Acidic Protein in Human Gliomas

(2014) Marco Skardelly et al.   Translational Oncology

Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children

(2010) Giada De Palma et al.   BMC MICROBIOLOGY

Prognostic and predictive value of 16p12.1 and 16q22.1 copy number changes in human breast cancer

(2010) Tricia E. Downing et al.   CANCER GENETICS AND CYTOGENETICS

Proteomics-based identification of haptoglobin as a novel plasma biomarker in oral squamous cell carcinoma

(2010) Chih-Ho Lai et al.   CLINICA CHIMICA ACTA

Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat

(2010) J. T. J. Visser et al.   DIABETOLOGIA

Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeability

(2010) Victorien M. Wolters et al.   HUMAN IMMUNOLOGY

Etiology of Type 1 Diabetes

(2010) John A. Todd   IMMUNITY

Intestinal Immune Regulation as a Potential Diet-Modifiable Feature of Gut Inflammation and Autoimmunity

(2010) Brigitte Sonier et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Unlocking the pathogenesis of celiac disease

(2010) Robert M Plenge   NATURE GENETICS

The Type 1 Diabetes - HLA Susceptibility Interactome - Identification of HLA Genotype-Specific Disease Genes for Type 1 Diabetes

(2010) Caroline Brorsson et al.   PLoS One

Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease

(2010) Dorottya Nagy Szakál et al.   VIRCHOWS ARCHIV

Proximal Small Intestinal Microbiota and Identification of Rod-Shaped Bacteria Associated With Childhood Celiac Disease

(2009) Gangwei Ou et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Chromosomal region 16p13: further evidence of increased predisposition to immune diseases

(2009) A Martinez et al.   ANNALS OF THE RHEUMATIC DISEASES

Diabetes-Specific HLA-DR-Restricted Proinflammatory T-Cell Response to Wheat Polypeptides in Tissue Transglutaminase Antibody-Negative Patients With Type 1 Diabetes

(2009) M. Mojibian et al.   DIABETES

M2038 PBMC from Celiac Patients But Not Healthy Controls Produce Interleukin-8 in Response to Gliadin That Is Cxcr3-Dependent

(2009) Karen M. Lammers et al.   GASTROENTEROLOGY

M2048 Safety, Tolerability and Effects On Intestinal Permeability of Larazotide Acetate in Celiac Disease: Results of a Phase IIB 6-Week Gluten-Challenge Clinical Trial

(2009) Ciaran P. Kelly et al.   GASTROENTEROLOGY

Celiac Disease: From Pathogenesis to Novel Therapies

(2009) Detlef Schuppan et al.   GASTROENTEROLOGY

Production of interferon-γ by activated T-cell receptor-αβ CD8αβ intestinal intraepithelial lymphocytes is required and sufficient for disruption of the intestinal barrier integrity

(2009) Christel Zufferey et al.   IMMUNOLOGY

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The genetics and epigenetics of autoimmune diseases

(2009) Anura Hewagama et al.   JOURNAL OF AUTOIMMUNITY

Intestinal T Cell Responses to Gluten Peptides Are Largely Heterogeneous: Implications for a Peptide-Based Therapy in Celiac Disease

(2009) A. Camarca et al.   JOURNAL OF IMMUNOLOGY

Role of Gut Commensal Microflora in the Development of Experimental Autoimmune Encephalomyelitis

(2009) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

An exploration of Glo-3A antibody levels in children at increased risk for type 1 diabetes mellitus

(2009) M Simpson et al.   PEDIATRIC DIABETES

Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2

(2009) A. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surprises from Celiac Disease

(2009) Alessio Fasano   SCIENTIFIC AMERICAN

Physiological, Pathological, and Therapeutic Implications of Zonulin-Mediated Intestinal Barrier Modulation

(2008) Alessio Fasano   AMERICAN JOURNAL OF PATHOLOGY

NKT Cell-Dependent Amelioration of a Mouse Model of Multiple Sclerosis by Altering Gut Flora

(2008) Hiroaki Yokote et al.   AMERICAN JOURNAL OF PATHOLOGY

Epigenetics in human autoimmunity

(2008) Faith M. Strickland et al.   AUTOIMMUNITY

Chromosomal evolution of the PKD1 gene family in primates

(2008) Stefan Kirsch et al.   BMC EVOLUTIONARY BIOLOGY

Diversity of tight junctions (TJs) between gastrointestinal epithelial cells and their function in maintaining the mucosal barrier

(2008) Q YU et al.   CELL BIOLOGY INTERNATIONAL

Translational Mini-Review Series on the Immunogenetics of Gut Disease: Immunogenetics of coeliac disease

(2008) P. C. Dubois et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Haptoglobin Polymorphism: A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations

(2008) M. Papp et al.   CLINICAL CHEMISTRY

Human haptoglobin structure and function - a molecular modelling study

(2008) F. Polticelli et al.   FEBS Journal

Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3

(2008) Karen M. Lammers et al.   GASTROENTEROLOGY

Mechanisms of epithelial translocation of the  2-gliadin-33mer in coeliac sprue

(2008) M Schumann et al.   GUT

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

(2008) M C Arrieta et al.   GUT

Association of Type 1 Diabetes with Two Loci on 12q13 and 16p13 and the Influence Coexisting Thyroid Autoimmunity in Japanese

(2008) Takuya Awata et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

(2008) Swapan K Nath et al.   NATURE GENETICS

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS

EGF receptor transactivation and MAP kinase mediate proteinase-activated receptor-2-induced chloride secretion in intestinal epithelial cells

(2007) Jacques Q. van der Merwe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gender-specific influence of the chromosome 16 chemokine gene cluster on the susceptibility to Multiple Sclerosis

(2007) Daniela Galimberti et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES