Carbonic anhydrase IX inhibitors in cancer therapy: an update

DNA-Encoded Chemical Libraries: Advancing beyond Conventional Small-Molecule Libraries

(2014) Raphael M. Franzini et al.   ACCOUNTS OF CHEMICAL RESEARCH

Plasmonic Particles that Hit Hypoxic Cells

(2014) Fulvio Ratto et al.   ADVANCED FUNCTIONAL MATERIALS

A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors

(2014) Nikolaus Krall et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development and biological evaluation of 99mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers

(2013) Vamsidhar Akurathi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anticancer carbonic anhydrase inhibitors: a patent review (2008 – 2013)

(2013) Simona Maria Monti et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Hypoxia-Targeting Carbonic Anhydrase IX Inhibitors by a New Series of Nitroimidazole-Sulfonamides/Sulfamides/Sulfamates

(2013) Marouan Rami et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs

(2013) Ludwig Dubois et al.   RADIOTHERAPY AND ONCOLOGY

Glycosidic carbonic anhydrase IX inhibitors: A sweet approach against cancer

(2012) Jean-Yves Winum et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines

(2012) Jean-Yves Winum et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-based drug discovery of carbonic anhydrase inhibitors

(2012) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Antimetastatic Effect of Sulfamate Carbonic Anhydrase IX Inhibitors in Breast Carcinoma Xenografts

(2012) Roben G. Gieling et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche

(2012) F E Lock et al.   ONCOGENE

Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

(2011) Y. Lou et al.   CANCER RESEARCH

Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors

(2011) Nadia Touisni et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis

(2011) Fabio Pacchiano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation

(2011) Ludwig Dubois et al.   RADIOTHERAPY AND ONCOLOGY

Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds

(2010) Fabian Buller et al.   ACS Chemical Biology

Carbonic Anhydrase IX as an Anticancer Therapy Target: Preclinical Evaluation of Internalizing Monoclonal Antibody Directed to Catalytic Domain

(2010) M. Zatovicova et al.   CURRENT PHARMACEUTICAL DESIGN

Carbonic anhydrase inhibition as a cancer therapy: a review of patent literature, 2007 – 2009

(2010) Sally-Ann Poulsen   EXPERT OPINION ON THERAPEUTIC PATENTS

Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia

(2010) Vamsidhar Akurathi et al.   NUCLEAR MEDICINE AND BIOLOGY

In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives

(2009) Julia K.J. Ahlskog et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model

(2009) Ludwig Dubois et al.   RADIOTHERAPY AND ONCOLOGY

Carbonic Anhydrase Inhibitor Coated Gold Nanoparticles Selectively Inhibit the Tumor-Associated Isoform IX over the Cytosolic Isozymes I and II

(2008) Maamar Stiti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Carbonic anhydrase IX: A new druggable target for the design of antitumor agents

(2007) Jean-Yves Winum et al.   MEDICINAL RESEARCH REVIEWS