Article
Biochemistry & Molecular Biology
ShuangShuang Gu, HuiQing Sun, XiaoLing Zhang, FuNing Huang, LiChao Pan, ZhenYuan Zhu
Summary: The novel acidic polysaccharide AWPA was extracted from Annona squamosa residue, characterized by various analytical methods, and showed potential inhibitory activity against α-glucosidase and α-amylase.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Applied
Alexandra Kremmyda, William MacNaughtan, Dimitris Arapoglou, Christos Eliopoulos, Maria Metafa, Stephen E. Harding, Cleanthes Israilides
Summary: The study focused on distinguishing beta-D-glucans from other carbohydrates in natural products, as well as determining glucan content and structural information through CP/MAS NMR spectra. Spectral peak fitting in the anomeric carbon C1 region revealed the possibility of clear distinction between beta-D-glucans and other carbohydrates, particularly in hydrated samples with enhanced resolution. Contamination by other carbohydrates and buffer salts was also discussed.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Jin Wang, Yunhai Wang, Xiaoqian Yang, Ping Lin, Na Liu, Xinjian Li, Baihui Zhang, Shoudong Guo
Summary: CM3-SII, a novel alkali-extracted polysaccharide from the fruiting body of C. militaris, enhances intracellular protein expression by regulating SREBP-2. It also significantly decreases PCSK9 secretion, showing potential applications in hypolipidemia or as a pharmaceutical additive.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Medicinal
Saptarshi Samajdar, K. Jayaram Kumar
Summary: This study characterized the water-soluble polysaccharide CGPS isolated from chironji gum and explored its nanoemulsifying properties. The results showed that CGPS had high nanoemulsifying performance and could be utilized in colon-targeted drug delivery systems.
PHARMACOGNOSY MAGAZINE
(2022)
Article
Biochemistry & Molecular Biology
Wan Li, Kexin Fang, Hao Yuan, Dongru Li, Haochen Li, Yin Chen, Xinyao Luo, Lian Zhang, Xiaochuan Ye
Summary: This study fabricates an acid-induced physical hydrogel based on natural PCAP, the main component of Poria cocos. The gelation behavior of PCAP at different pH and concentration is explored, revealing the dominant roles of hydrogen bonds and hydrophobic interactions. The PCAP hydrogel exhibits a porous network structure and various beneficial properties, including viscoelasticity, cytocompatibility, water-holding capability, antioxidant and anti-inflammatory activities. Additionally, the release of a model drug from the PCAP hydrogel is pH-dependent. These findings highlight the potential of PCAP hydrogels in biological medicine and drug delivery.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Katharina Dilchert, Michelle Schmidt, Angela Grossjohann, Kai-Stephan Feichtner, Robert E. Mulvey, Viktoria H. Gessner
Summary: s-Block metal carbenoids are carbene synthons used in a variety of organic transformations. While sodium and potassium chloride carbenoids exhibit high stabilities in all solvents, the stability of lithium carbenoid varies depending on the solvent.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Plant Sciences
Khong Trong Quan, InWha Park, Chung Sub Kim, Wesley Yoshida, Daneel Ferreira, Phuong Thien Thuong, Young Ho Kim, MinKyun Na, Joonseok Oh
Summary: A new benzo[g]isochromene with a conformationally mobile moiety was isolated from Rubia philippinensis. Advanced computational tools and compositional/molecular orbital analyses supported the configurational assignment. Compound 1 showed inhibitory effects on soluble epoxide hydrolase, which is linked to cardiovascular disorders.
JOURNAL OF NATURAL PRODUCTS
(2021)
Article
Chemistry, Multidisciplinary
Sinead McCann, William E. Roe, Hannah E. Agnew, Peter C. Knipe
Summary: To imitate the dynamic molecules in biological systems, foldamers need to possess stimulus-responsive behavior. In this study, we present a foldamer architecture based on alternating pyridine-diketopiperazine linkers. Epimerization is prevented via a copper-catalyzed coupling protocol. The native conformation of the compounds is initially investigated in both solid and solution states. The foldamers can be solubilized in DMSO and pH 9.5 buffer while retaining conformational control. Furthermore, dynamic switching is demonstrated through acid treatment, resulting in stimulus-responsive sidechain reconfiguration.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Applied
Christiane F. Ellefsen, Linda Lindstad, Leesa J. Klau, Finn L. Aachmann, Marianne Hiorth, Anne Berit C. Samuelsen
Summary: This study extracted and characterized the β-glucans from the edible mushroom Pleurotus eryngii, and found that they contain structurally different polysaccharides. However, these polysaccharides were unable to induce the production of proinflammatory cytokines in LPS-differentiated THP-1 cells, despite being able to activate the human dectin-1a receptor.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Edina Sic, Jochen Rohrer, Emmanuel Ricohermoso, Karsten Albe, Emmanuel Ionescu, Ralf Riedel, Hergen Breitzke, Torsten Gutmann, Gerd Buntkowsky
Summary: Polymer-derived silicon oxycarbide ceramics (SiCO) have been investigated as potential anode materials for lithium- and sodium-ion batteries. This study focuses on understanding the local structures of SiCO ceramics with different amounts of carbon. Through various spectroscopic and computational techniques, significant changes in the local structures of SiCO ceramics have been observed, even with small changes in the material composition. These findings will provide valuable insights into the electrochemical storage processes of alkali metal/ions inside polymer-derived ceramics, particularly in the context of future research.
Article
Food Science & Technology
Yu Zhou, Jinjin Zhao, Junjie Guo, Xijun Lian, Huaiwen Wang
Summary: This study investigates the effects of adding wheat, maize, cassava, mung bean, and sweet potato starches to dough systems for improving their hardness. Inconsistent effects on dough quality, especially in refrigerated dough, have been reported. The study also analyzes the disulfide bond contents of alkali-soluble glutenin (ASG) and proposes a pathway of disulfide bond formation in ASGs. The results show that the addition of wheat amylopectin promotes the most significant disulfide bond formation in ASG.
Article
Biochemistry & Molecular Biology
Yan Zhao, Yingying Feng, Xue Jing, Yining Liu, Anjun Liu
Summary: A novel alkali-soluble polysaccharide (AASP) isolated from Angelica sinensis showed significant antitumor activity in Vivo, by promoting immunocyte proliferation and cytokine release, inducing apoptosis of tumor cells.
CHEMISTRY & BIODIVERSITY
(2021)
Article
Construction & Building Technology
Pedro Perez-Cortes, Karina Cabrera-Luna, J. Ivan Escalante-Garcia
Summary: Alkali-activated limestone/metakaolin pastes were exposed to different temperatures, with weight reduction at 300°C, reactions/dissolution at 600°C, and formation of new compounds at 900°C, leading to significant strength reduction. These findings provide insights into potential high-temperature applications of AAC-LSMK.
CEMENT & CONCRETE COMPOSITES
(2021)
Review
Polymer Science
Svetlana R. Derkach, Nikolay G. Voron'ko, Yulia A. Kuchina
Summary: This review summarizes recent advances in the study of polysaccharide-gelatin complexes, focusing on data obtained by spectroscopic methods. The discussion highlights the complexing polysaccharides of marine origin, such as sodium alginate, kappa-carrageenan, and chitosan. The prospects for creating polysaccharide-gelatin complexes with desired physicochemical properties are outlined.
Article
Food Science & Technology
Li Xing, Yelian Miao, Na Li, Ling Jiang, Jie Yu Chen
Summary: Polysaccharides extracted from Dendrobium officinale showed proliferative effect on LAB and bifidobacteria, with ADOP2 being the most effective. During lactic acid fermentation, ADOP2 and WDOP produced more short-chain fatty acids compared to ADOP1 and ADOP3.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2021)
Article
Food Science & Technology
Agnieszka Zawadzka, Joanna Kobus-Cisowska, Dominik Szwajgier, Oskar Szczepaniak, Piotr Szulc, Marek Siwulski
Summary: This study evaluated the effect of drying and extraction processes from selected edible mushrooms on inhibitory activity against cholinesterases and complexation of aluminum ions. The results showed that the tested mushroom samples exhibited inhibitory activity against enzymes and the ability to complex aluminum ions, with convection drying being a more favorable dehydration method.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Klaudia Kowalik, Magdalena Polak-Berecka, Monika Prendecka-Wrobel, Dominika Pigon-Zajac, Iwona Niedzwiedz, Dominik Szwajgier, Ewa Baranowska-Wojcik, Adam Wasko
Summary: This study examined the biological activity of an in vitro digested infusion of Epilobium angustifolium (fireweed) in a model system of intestinal epithelial and colon cancer tissues. The results showed that the infusion inhibited the growth of intestinal cancer cells HT-29, which can be attributed to the activity of quercetin and kaempferol. The cytotoxic effect of the infusion was dose-dependent, and it did not affect the growth of beneficial intestinal bacteria but significantly inhibited E. coli.
Article
Multidisciplinary Sciences
Agnieszka Zawadzka, Anna Janczewska, Joanna Kobus-Cisowska, Marcin Dziedzinski, Marek Siwulski, Ewa Czarniecka-Skubina, Kinga Stuper-Szablewska
Summary: This study evaluated the effect of light conditions on the retention of vitamins, minerals, and polyphenols in oyster mushrooms and their antioxidant activity. The results showed that higher light intensity increased the riboflavin content in the mushrooms, while decreasing light intensity reduced the thiamine content. The biologically active compounds were found to be equal in the stem and cap, but the riboflavin content was higher in the cap. The mineral composition differed between the cap and stem, with lower iron, magnesium, and sodium content in the stem. Limited light exposure increased the total polyphenolic compound content, but did not affect antioxidant activity. Stem extracts had higher antioxidant activity compared to cap extracts.
Article
Environmental Sciences
Miroslaw Mleczek, Anna Budka, Marek Siwulski, Sylwia Budzynska, Pavel Kalac, Zbigniew Karolewski, Marta Lisiak-Zielinska, Natalia Kuczynska-Kippen, Przemyslaw Niedzielski
Summary: The study analyzed the mineral composition of soil, trees, and mushroom species collected from within a city and from rural areas, finding significantly higher concentrations of several elements in urban samples. While urban mushrooms generally have higher levels of mineral elements, this does not necessarily pose a real risk when consuming those samples.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Miroslaw Mleczek, Malgorzata Szostek, Marek Siwulski, Anna Budka, Pavel Kalac, Sylwia Budzynska, Natalia Kuczynska-Kippen, Przemyslaw Niedzielski
Summary: The research investigates the effects of road traffic and soil chemical characteristics on the mineral composition of Macrolepiota procera fruit bodies growing near a road and a forest. Findings indicate that variations in soil elements concentrations lead to differences in mineral composition of the fruit bodies.
Article
Biochemistry & Molecular Biology
Marta Kinga Lemieszek, Iwona Komaniecka, Michal Chojnacki, Adam Choma, Wojciech Rzeski
Summary: The water extract from young green barley (YGB) has been found to have a beneficial impact on natural killer (NK) cells' ability to recognize and eliminate human colon cancer cells. This extract also exhibits a direct anticancer effect. The mixture of oligosaccharides found in the extract consists mainly of glucose and fructose, with a small amount of mannose and galactose.
Article
Environmental Sciences
Ewa Sajnaga, Marcin Skowronek, Agnieszka Kalwasinska, Waldemar Kazimierczak, Magdalena Lis, Monika Elzbieta Jach, Adrian Wiater
Summary: This study provides the first detailed characterization of the bacterial community of the midgut in wild A. solstitiale larvae and reveals that the gut microbiota alteration is associated with resistant insects. Further research on the role of gut microbiota in insect-parasitic nematode interaction may enhance biological control strategies in insect pest management.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Chemistry, Multidisciplinary
Monika Kordowska-Wiater, Monika Pytka, Anna Stoj, Agnieszka Kubik-Komar, Jakub Wyrostek, Adam Wasko
Summary: The study focused on the microbial diversity and key properties of Polish red wines produced by spontaneous fermentation. It identified the most abundant bacterial and yeast species in the wines from different vineyards and noted significant differences in antioxidant capacities and concentrations of glucose, fructose, and lactic acid. The findings highlighted the importance of indigenous strains for the development of unique local starter cultures and the production of wines with specific characteristics.
APPLIED SCIENCES-BASEL
(2022)
Review
Food Science & Technology
Michal Czelej, Katarzyna Garbacz, Tomasz Czernecki, Jacek Wawrzykowski, Adam Wasko
Summary: There is significant interest in the use of animal, plant, and fungal sources for the production of bioactive peptides. These sources offer cheap and environmentally friendly material, often including waste and by-products. Enzymatic hydrolysis is an efficient method for obtaining peptides with antioxidant activity.
Letter
Environmental Sciences
Miroslaw Mleczek, Anna Budka, Marek Siwulski, Sylwia Budzynaka, Pavel Kalac, Zbigniew Karolewski, Marta Lisiak, Natalia Kuczynska-Kippen, Przemyslaw Niedzielski
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Pharmacology & Pharmacy
Daniel Augustynowicz, Marta Kinga Lemieszek, Jakub Wladyslaw Strawa, Adrian Wiater, Michal Tomczyk
Summary: Cinquefoils have been widely used in folk medicine for managing gastrointestinal diseases, cancer, thyroid disorders, and wound healing. In this study, extracts from different Potentilla species were analyzed for their cytotoxic and antiproliferative effects on colon cancer cells. The results showed that these extracts had stronger effects on cancer cells compared to normal cells, suggesting their potential as anti-colorectal cancer agents.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Applied
Przemyslaw Niedzielski, Malgorzata Szostek, Anna Budka, Sylwia Budzynska, Marek Siwulski, Jedrzej Proch, Pavel Kalac, Miroslaw Mleczek
Summary: The efficiency of mineral element accumulation in mushrooms is significantly influenced by mushroom species, with species belonging to the Lactarius genus containing higher amounts of major elements compared to species in the Russula genus. The results also suggest that specific species within each genus have significantly higher element content, indicating the essential role of both mushroom species and genera in modulating element accumulation.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Biochemistry & Molecular Biology
Jakub W. Strawa, Katarzyna Jakimiuk, Bozena Pawlikowska-Pawlega, Wieslaw Gruszecki, Justyna Kapral-Piotrowska, Adrian Wiater, Michal Tomczyk
Summary: The aim of this study was to investigate the interaction, location, and influence of flavonoids isolated from two plant species on model lipid membranes. The results showed that these compounds incorporated into the polar head region or water/membrane interface of the lipid membranes. They affected the ester carbonyl groups and caused reorganization of the polar zone of the liposomes. The NMR technique confirmed the locations of the compounds and revealed their modifying effect towards lipid membranes.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2023)
Article
Biochemistry & Molecular Biology
Daniel Augustynowicz, Marta Kinga Lemieszek, Jakub Wladyslaw Strawa, Adrian Wiater, Michal Tomczyk
Summary: This study evaluated the phytochemical and biological properties of aqueous acetone extracts from selected Potentilla species. The results showed that some of these extracts have potential anticancer effects, encouraging further research for the development of a new therapeutic strategy for colon cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Justyna Kapral-Piotrowska, Jakub W. Strawa, Katarzyna Jakimiuk, Adrian Wiater, Michal Tomczyk, Wieslaw I. Gruszecki, Bozena Pawlikowska-Pawlega
Summary: This report discusses the effects of newly isolated flavone derivatives HZ4 and SP9 from Hottonia palustris L. and Scleranthus perennis L. on membranes. Experimental results showed that these compounds interact with the polar head group region of lipid bilayers, causing changes in the spectral regions. NMR analyses confirmed the localization of these compounds in the polar heads zone. These findings are crucial for determining the biological activities and medicinal usability of these compounds.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.