Regulation of neuronal development and function by ROS

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

(2017) Silvia Sorce et al.   FREE RADICAL BIOLOGY AND MEDICINE

How does calcium interact with the cytoskeleton to regulate growth cone motility during axon pathfinding?

(2017) Robert J. Gasperini et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neuronal polarization: From spatiotemporal signaling to cytoskeletal dynamics

(2017) Max Schelski et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia

(2017) P Steullet et al.   MOLECULAR PSYCHIATRY

Integration of optogenetics with complementary methodologies in systems neuroscience

(2017) Christina K. Kim et al.   NATURE REVIEWS NEUROSCIENCE

Establishing Neuronal Polarity with Environmental and Intrinsic Mechanisms

(2017) Shaul Yogev et al.   NEURON

The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling

(2017) Sumbul Jawed Khan et al.   PLoS Genetics

Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking

(2016) Bruce E. Herring et al.   Annual Review of Physiology

Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes

(2016) Paul S. Baxter et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification

(2016) C. Wilson et al.   JOURNAL OF NEUROSCIENCE

F-actin dismantling through a redox-driven synergy between Mical and cofilin

(2016) Elena E. Grintsevich et al.   NATURE CELL BIOLOGY

Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes

(2016) Bruce Morgan et al.   Nature Chemical Biology

Nox/Duox Family of NADPH Oxidases: Lessons from Knockout Mouse Models

(2016) Gábor Sirokmány et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondrial redox and pH signaling occurs in axonal and synaptic organelle clusters

(2016) Michael O. Breckwoldt et al.   Scientific Reports

Persistent activation of microglia and NADPH oxidase drive hippocampal dysfunction in experimental multiple sclerosis

(2016) Massimiliano Di Filippo et al.   Scientific Reports

Inflammation-induced radioresistance is mediated by ROS-dependent inactivation of protein phosphatase 1 in non-small cell lung cancer cells

(2015) Wanyeon Kim et al.   APOPTOSIS

ROS Produced by NOX2 Controls In Vitro Development of Cerebellar Granule Neurons Development

(2015) Mauricio Olguín-Albuerne et al.   ASN Neuro

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway

(2015) D Jimenez-Blasco et al.   CELL DEATH AND DIFFERENTIATION

SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents

(2015) Yuzheng Zhao et al.   Cell Metabolism

Contribution of NADPH oxidase to the establishment of hippocampal neuronal polarity in culture

(2015) C. Wilson et al.   JOURNAL OF CELL SCIENCE

Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia

(2015) Kim Q. Do et al.   SCHIZOPHRENIA BULLETIN

Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

(2015) Paul S. Baxter et al.   Nature Communications

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

(2015) Karen F.S. Bell et al.   Nature Communications

Specific aquaporins facilitate Nox-produced hydrogen peroxide transport through plasma membrane in leukaemia cells

(2014) Francesco Vieceli Dalla Sega et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Bidirectional interactions between NOX2-type NADPH oxidase and the F-actin cytoskeleton in neuronal growth cones

(2014) Vidhya Munnamalai et al.   JOURNAL OF NEUROCHEMISTRY

Second messenger networks for accurate growth cone guidance

(2013) Hiroki Akiyama et al.   Developmental Neurobiology

Retrograde BMP Signaling at the Synapse: A Permissive Signal for Synapse Maturation and Activity-Dependent Plasticity

(2013) B. Berke et al.   JOURNAL OF NEUROSCIENCE

SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics

(2013) Ruei-Jiun Hung et al.   NATURE CELL BIOLOGY

Dendritic growth gated by a steroid hormone receptor underlies increases in activity in the developing Drosophila locomotor system

(2013) M. F. Zwart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perineuronal nets protect fast-spiking interneurons against oxidative stress

(2013) J.-H. Cabungcal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipofuscin: formation, effects and role of macroautophagy

(2013) Annika Höhn et al.   Redox Biology

HyPer-3: A Genetically Encoded H2O2 Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging

(2012) Dmitry S. Bilan et al.   ACS Chemical Biology

Redox-Sensitive Oxidation and Phosphorylation of PTEN Contribute to Enhanced Activation of PI3K/Akt Signaling in Rostral Ventrolateral Medulla and Neurogenic Hypertension in Spontaneously Hypertensive Rats

(2012) Kay L.H. Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species-Induced Actin Glutathionylation Controls Actin Dynamics in Neutrophils

(2012) Jiro Sakai et al.   IMMUNITY

Presynaptic PI3K activity triggers the formation of glutamate receptors at neuromuscular terminals of Drosophila

(2012) S. Jordan-Alvarez et al.   JOURNAL OF CELL SCIENCE

Reactive Oxygen Species Regulate Protrusion Efficiency by Controlling Actin Dynamics

(2012) Nicolas Taulet et al.   PLoS One

MICALs in control of the cytoskeleton, exocytosis, and cell death

(2011) Yeping Zhou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidative stress in synapse development and function

(2011) Valerie J. Milton et al.   Developmental Neurobiology

Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal Neurons

(2011) G. Cuesto et al.   JOURNAL OF NEUROSCIENCE

Calcium/Calmodulin-Dependent Kinase II Mediates the Phosphorylation and Activation of NADPH Oxidase 5

(2011) D. Pandey et al.   MOLECULAR PHARMACOLOGY

The Oriented Emergence of Axons from Retinal Ganglion Cells Is Directed by Laminin Contact In Vivo

(2011) Owen Randlett et al.   NEURON

Opposite modulation of time course of quantal release in two parts of the same synapse by reactive oxygen species

(2011) A. Tsentsevitsky et al.   NEUROSCIENCE

Oxidative stress induces overgrowth of the Drosophila neuromuscular junction

(2011) V. J. Milton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Redox Regulation of F-Actin Assembly and Disassembly by Mical

(2011) R.-J. Hung et al.   SCIENCE

Thioredoxin Mediates Oxidation-Dependent Phosphorylation of CRMP2 and Growth Cone Collapse

(2011) A. Morinaka et al.   Science Signaling

Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

(2011) David A. Lewis et al.   TRENDS IN NEUROSCIENCES

The Role of Cysteine Oxidation in DJ-1 Function and Dysfunction

(2010) Mark A. Wilson   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

(2010) Cynthia A. Massaad et al.   ANTIOXIDANTS & REDOX SIGNALING

PKC delta and NADPH oxidase in retinoic acid-induced neuroblastoma cell differentiation

(2010) Mariapaola Nitti et al.   CELLULAR SIGNALLING

Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals

(2010) Jesús Aguirre et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mical links semaphorins to F-actin disassembly

(2010) Ruei-Jiun Hung et al.   NATURE

Cell polarity triggered by cell-cell adhesion via E-cadherin

(2009) R. A. Desai et al.   JOURNAL OF CELL SCIENCE

Disorders of biopterin metabolism

(2009) Nicola Longo   JOURNAL OF INHERITED METABOLIC DISEASE

Involvement of Reactive Oxygen Species in Long-Term Potentiation in the Spinal Cord Dorsal Horn

(2009) Kwan Yeop Lee et al.   JOURNAL OF NEUROPHYSIOLOGY

JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy

(2009) Hai Wu et al.   MECHANISMS OF DEVELOPMENT

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Regulation of Apical Dominance in Aspergillus nidulans Hyphae by Reactive Oxygen Species

(2008) C. P. Semighini et al.   GENETICS

Reactive oxygen species regulate F-actin dynamics in neuronal growth cones and neurite outgrowth

(2008) Vidhya Munnamalai et al.   JOURNAL OF NEUROCHEMISTRY

Release of MICAL Autoinhibition by Semaphorin-Plexin Signaling Promotes Interaction with Collapsin Response Mediator Protein

(2008) E. F. Schmidt et al.   JOURNAL OF NEUROSCIENCE

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis

(2003) Alberto Ferri et al.   JOURNAL OF NEUROCHEMISTRY