Inflammation-induced radioresistance is mediated by ROS-dependent inactivation of protein phosphatase 1 in non-small cell lung cancer cells

NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor

(2015) Lan Yu et al.   Oncotarget

Isofraxidin, a potent reactive oxygen species (ROS) scavenger, protects human leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in p53-independent manner

(2014) Peng Li et al.   APOPTOSIS

ATDC/TRIM29 Phosphorylation by ATM/MAPKAP Kinase 2 Mediates Radioresistance in Pancreatic Cancer Cells

(2014) Lidong Wang et al.   CANCER RESEARCH

PAK1 Tyrosine Phosphorylation Is Required to Induce Epithelial-Mesenchymal Transition and Radioresistance in Lung Cancer Cells

(2014) E. Kim et al.   CANCER RESEARCH

Ras-induced ROS upregulation affecting cell proliferation is connected with cell type-specific alterations of HSF1/SESN3/p21Cip1/WAF1pathways

(2013) Maria Zamkova et al.   CELL CYCLE

Lipopolysaccharide-Induced Inflammation Aggravates Irradiation-Induced Injury to the Young Mouse Brain

(2013) Karolina Roughton et al.   DEVELOPMENTAL NEUROSCIENCE

Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status

(2013) Razmik Mirzayans et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activation of p53 with Nutlin-3a radiosensitizes lung cancer cells via enhancing radiation-induced premature senescence

(2013) Hongmei Luo et al.   LUNG CANCER

PIM1 kinase inhibitors induce radiosensitization in non-small cell lung cancer cells

(2013) Wanyeon Kim et al.   PHARMACOLOGICAL RESEARCH

The TNF-α/ROS/HIF-1-induced Upregulation of FoxMI Expression Promotes HCC Proliferation and Resistance to Apoptosis

(2012) Limin Xia et al.   CARCINOGENESIS

Protein Ser/ Thr phosphatases - the ugly ducklings of cell signalling

(2012) David L. Brautigan   FEBS Journal

Personalized Targeted Therapy for Lung Cancer

(2012) Kehua Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phosphorylation of Ribosomal Protein S3 and Antiapoptotic TRAF2 Protein Mediates Radioresistance in Non-small Cell Lung Cancer Cells

(2012) Hee Jung Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

2-Deoxy-d-glucose and ferulic acid modulates radiation response signaling in non-small cell lung cancer cells

(2012) Venkata Reddy Bandugula et al.   TUMOR BIOLOGY

Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation

(2011) Hee Jung Yang et al.   BIOCHEMICAL PHARMACOLOGY

Multifaceted link between cancer and inflammation

(2011) Gautam Sethi et al.   BIOSCIENCE REPORTS

Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury

(2011) Edouard I. Azzam et al.   CANCER LETTERS

Targeted agents in non-small cell lung cancer (NSCLC): Clinical developments and rationale for the combination with thoracic radiotherapy

(2011) Pek Keng Koh et al.   CANCER TREATMENT REVIEWS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Chronic inflammation, the tumor microenvironment and carcinogenesis

(2011) Tamas A. Gonda et al.   CELL CYCLE

PIM1-Activated PRAS40 Regulates Radioresistance in Non-small Cell Lung Cancer Cells through Interplay with FOXO3a, 14-3-3 and Protein Phosphatases

(2011) Wanyeon Kim et al.   RADIATION RESEARCH

Myricetin Inhibits Akt Survival Signaling and Induces Bad-mediated Apoptosis in a Low Dose Ultraviolet (UV)-B-irradiated HaCaT Human Immortalized Keratinocytes

(2010) Wanyeon KIM et al.   JOURNAL OF RADIATION RESEARCH

Serine/threonine phosphatases in the DNA damage response and cancer

(2010) A Peng et al.   ONCOGENE

Curcumin Modulates the Radiosensitivity of Colorectal Cancer Cells by Suppressing Constitutive and Inducible NF-κB Activity

(2009) Santosh K. Sandur et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Effect of Compound K, a Metabolite of Ginseng Saponin, Combined with γ-Ray Radiation in Human Lung Cancer Cells in Vitro and in Vivo

(2009) Sungwook Chae et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

(2008) Johan Bussink et al.   LANCET ONCOLOGY

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair

(2008) M. Toulany et al.   MOLECULAR CANCER THERAPEUTICS