The histone demethylase KDM5A is required for the repression of astrocytogenesis and regulated by the translational machinery in neural progenitor cells

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice

(2017) Chie Naruse et al.   FASEB JOURNAL

Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells

(2016) Yael Yoffe et al.   GENES & DEVELOPMENT

Inhibition of the histone demethylase Kdm5b promotes neurogenesis and derepresses Reln (reelin) in neural stem cells from the adult subventricular zone of mice

(2016) Qiong Zhou et al.   MOLECULAR BIOLOGY OF THE CELL

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

(2016) Maia Vinogradova et al.   Nature Chemical Biology

LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling the Expression of a Novel Target Gene, HEYL

(2016) Kazumi Hirano et al.   STEM CELLS

Genetics and Epigenetics in Adult Neurogenesis

(2016) Jenny Hsieh et al.   Cold Spring Harbor Perspectives in Biology

KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis

(2016) Chuandong Wang et al.   Cell Death & Disease

H3K4me3 Demethylase Kdm5a Is Required for NK Cell Activation by Associating with p50 to Suppress SOCS1

(2016) Dezhi Zhao et al.   Cell Reports

Discovery of a Small Molecule that Enhances Astrocytogenesis by Activation of STAT3, SMAD1/5/8, and ERK1/2 via Induction of Cytokines in Neural Stem Cells

(2015) Ha-Rim Lee et al.   ACS Chemical Neuroscience

Signalling to eIF4E in cancer

(2015) N. Siddiqui et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mnks, eIF4E phosphorylation and cancer

(2015) Christopher G. Proud   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The histone demethylase KDM1A is essential for the maintenance and differentiation of spermatogonial stem cells and progenitors

(2015) Romain Lambrot et al.   FASEB JOURNAL

Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells

(2015) Renáta Váraljai et al.   GENES & DEVELOPMENT

BDNF Stimulation of Protein Synthesis in Cortical Neurons Requires the MAP Kinase-Interacting Kinase MNK1

(2015) M. Genheden et al.   JOURNAL OF NEUROSCIENCE

Targeting the translation machinery in cancer

(2015) Mamatha Bhat et al.   NATURE REVIEWS DRUG DISCOVERY

Kuwanon V Inhibits Proliferation, Promotes Cell Survival and Increases Neurogenesis of Neural Stem Cells

(2015) Sun-Young Kong et al.   PLoS One

Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance

(2014) Feng Zhang et al.   Nature Communications

Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes

(2014) Christos G. Gkogkas et al.   Cell Reports

Aminopropyl carbazole analogues as potent enhancers of neurogenesis

(2013) Hye Jin Yoon et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Before It Gets Started: Regulating Translation at the 5′ UTR

(2012) Patricia R. Araujo et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Translational control in cellular and developmental processes

(2012) Jian Kong et al.   NATURE REVIEWS GENETICS

Molecular mechanisms and potential functions of histone demethylases

(2012) Susanne Marije Kooistra et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases

(2011) B. W. Konicek et al.   CANCER RESEARCH

Jarid1b targets genes regulating development and is involved in neural differentiation

(2011) Sandra U Schmitz et al.   EMBO JOURNAL

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line

(2010) Christine Vogel et al.   Molecular Systems Biology

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

(2010) L. Furic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human UPF1 Participates in Small RNA-Induced mRNA Downregulation

(2009) H. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer Therapy

(2008) J. R. Graff et al.   CANCER RESEARCH

Genome-wide Analysis of the H3K4 Histone Demethylase RBP2 Reveals a Transcriptional Program Controlling Differentiation

(2008) Nuria Lopez-Bigas et al.   MOLECULAR CELL

The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif

(2008) Shengjiang Tu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regionally Specified Human Neural Progenitor Cells Derived from the Mesencephalon and Forebrain Undergo Increased Neurogenesis Following Overexpression of ASCL1

(2008) Hyun-Jung Kim et al.   STEM CELLS