Translational control in cellular and developmental processes

A conserved PUF–Ago–eEF1A complex attenuates translation elongation

(2012) Kyle Friend et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

(2011) R. Horos et al.   BLOOD

Translational Control via Protein-Regulated Upstream Open Reading Frames

(2011) Jan Medenbach et al.   CELL

Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning

(2011) Nadya Kondrashov et al.   CELL

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

A late phase of germ plasm accumulation during Drosophila oogenesis requires Lost and Rumpelstiltskin

(2011) Kristina S. Sinsimer et al.   DEVELOPMENT

Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm

(2011) T. Tanaka et al.   DEVELOPMENT

Mechanisms of dendritic mRNA transport and its role in synaptic tagging

(2011) Michael Doyle et al.   EMBO JOURNAL

CPEB2-eEF2 interaction impedes HIF-1α RNA translation

(2011) Po-Jen Chen et al.   EMBO JOURNAL

CUP promotes deadenylation and inhibits decapping of mRNA targets

(2011) C. Igreja et al.   GENES & DEVELOPMENT

Knockdown of ribosomal protein S7 causes developmental abnormalities via p53 dependent and independent pathways in zebrafish

(2011) Juan Duan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Mechanism of Insulin-stimulated 4E-BP Protein Binding to Mammalian Target of Rapamycin (mTOR) Complex 1 and Its Contribution to mTOR Complex 1 Signaling

(2011) Joseph Rapley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compartment-specific, differential regulation of eukaryotic elongation factor 2 and its kinase within Aplysia sensory neurons

(2011) Daniel B. Weatherill et al.   JOURNAL OF NEUROCHEMISTRY

Regulation of molecular pathways in the Fragile X Syndrome: insights into Autism Spectrum Disorders

(2011) Silvia De Rubeis et al.   Journal of Neurodevelopmental Disorders

rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells

(2011) Karen Jack et al.   MOLECULAR CELL

Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step

(2011) George S. Hussey et al.   MOLECULAR CELL

CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation

(2011) David M. Burns et al.   NATURE

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Loss of ribosomal RNA modification causes developmental defects in zebrafish

(2011) Sayomi Higa-Nakamine et al.   NUCLEIC ACIDS RESEARCH

Dimerization of oskar 3' UTRs promotes hitchhiking for RNA localization in the Drosophila oocyte

(2011) H. Jambor et al.   RNA

Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae

(2011) V. Balagopal et al.   RNA

A Cytoplasmic Complex Mediates Specific mRNA Recognition and Localization in Yeast

(2011) Marisa Müller et al.   PLOS BIOLOGY

Posttranscriptional regulation in Drosophila oocytes and early embryos

(2011) Paul Lasko   Wiley Interdisciplinary Reviews-RNA

Upstream open reading frames: Molecular switches in (patho)physiology

(2010) Klaus Wethmar et al.   BIOESSAYS

Loss of Function of the Tumor Suppressor DKC1 Perturbs p27 Translation Control and Contributes to Pituitary Tumorigenesis

(2010) C. Bellodi et al.   CANCER RESEARCH

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

(2010) Fabio Demontis et al.   CELL

RNA granules: The good, the bad and the ugly

(2010) María Gabriela Thomas et al.   CELLULAR SIGNALLING

Smaug assembles an ATP-dependent stable complex repressingnanosmRNA translation at multiple levels

(2010) Mandy Jeske et al.   EMBO JOURNAL

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita

(2010) Cristian Bellodi et al.   EMBO JOURNAL

Localization, anchoring and translational control ofoskar,gurken,bicoidandnanosmRNA during Drosophila oogenesis

(2010) Jan-Michael Kugler et al.   FLY

ZBP1 recognition of  -actin zipcode induces RNA looping

(2010) J. A. Chao et al.   GENES & DEVELOPMENT

Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud

(2010) Z. Shen et al.   GENES & DEVELOPMENT

Understanding neuronal connectivity through the post-transcriptional toolkit

(2010) C. M. Loya et al.   GENES & DEVELOPMENT

5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage

(2010) J. Chen et al.   GENES & DEVELOPMENT

Multiple Myo4 motors enhanceASH1mRNA transport inSaccharomyces cerevisiae

(2010) Sunglan Chung et al.   JOURNAL OF CELL BIOLOGY

Regulation of tumor suppressor p53 at the RNA level

(2010) Anna Vilborg et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Cap- and IRES-independent scanning mechanism of translation initiation as an alternative to the concept of cellular IRESs

(2010) Ivan N. Shatsky et al.   MOLECULES AND CELLS

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

(2010) Christel Rouget et al.   NATURE

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins

(2010) Andrew G. Cridge et al.   NUCLEIC ACIDS RESEARCH

Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F

(2010) R. Cencic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DDX6 recruits translational silenced human reticulocyte 15-lipoxygenase mRNA to RNP granules

(2010) I. S. Naarmann et al.   RNA

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

(2010) R. J. O. Dowling et al.   SCIENCE

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

mRNA Localization: Gene Expression in the Spatial Dimension

(2009) Kelsey C. Martin et al.   CELL

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

The multiple levels of regulation by p53 ubiquitination

(2009) J T Lee et al.   CELL DEATH AND DIFFERENTIATION

Toward a structural understanding of IRES RNA function

(2009) Megan E Filbin et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The maternal-to-zygotic transition: a play in two acts

(2009) W. Tadros et al.   DEVELOPMENT

Dynamic organization and plasticity of sponge bodies

(2009) Mark J. Snee et al.   DEVELOPMENTAL DYNAMICS

Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor

(2009) M. Dienstbier et al.   GENES & DEVELOPMENT

Making synaptic plasticity and memory last: mechanisms of translational regulation

(2009) J. D. Richter et al.   GENES & DEVELOPMENT

Vasa promotes Drosophila germline stem cell differentiation by activating mei-P26 translation by directly interacting with a (U)-rich motif in its 3' UTR

(2009) N. Liu et al.   GENES & DEVELOPMENT

Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation

(2009) F. Besse et al.   GENES & DEVELOPMENT

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2

(2009) T. Katoh et al.   GENES & DEVELOPMENT

The p53 Tumor Suppressor Causes Congenital Malformations in Rpl24-Deficient Mice and Promotes Their Survival

(2009) M. Barkic et al.   MOLECULAR AND CELLULAR BIOLOGY

The SXL-UNR Corepressor Complex Uses a PABP-Mediated Mechanism to Inhibit Ribosome Recruitment to msl-2 mRNA

(2009) Kent E. Duncan et al.   MOLECULAR CELL

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

(2009) Luke S Tain et al.   NATURE NEUROSCIENCE

RNA granules: post-transcriptional and epigenetic modulators of gene expression

(2009) Paul Anderson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cytoplasmic Prep1 Interacts with 4EHP Inhibiting Hoxb4 Translation

(2009) J. Carlos Villaescusa et al.   PLoS One

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Ribosomal Protein L5 and L11 Mutations Are Associated with Cleft Palate and Abnormal Thumbs in Diamond-Blackfan Anemia Patients

(2008) Hanna T. Gazda et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia

(2008) J. E. Farrar et al.   BLOOD

In Vivo Imaging of oskar mRNA Transport Reveals the Mechanism of Posterior Localization

(2008) Vitaly L. Zimyanin et al.   CELL

The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP

(2008) Ilaria Napoli et al.   CELL

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

(2008) Yuzuru Imai et al.   EMBO JOURNAL

CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation

(2008) D. M. Burns et al.   GENES & DEVELOPMENT

Impaired myelopoiesis in mice lacking the repressors of translation initiation, 4E-BP1 and 4E-BP2

(2008) Katie E. Olson et al.   IMMUNOLOGY

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

(2008) Yaara Ofir-Rosenfeld et al.   MOLECULAR CELL

A deadenylation negative feedback mechanism governs meiotic metaphase arrest

(2008) Eulàlia Belloc et al.   NATURE

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions

(2008) Stavroula Mili et al.   NATURE

Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

(2008) Trilochan Sahoo et al.   NATURE GENETICS

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

(2008) Kelly A McGowan et al.   NATURE GENETICS

Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD

(2008) Sungjin Park et al.   NEURON