Tetrandrine attenuates the bone erosion in collagen-induced arthritis rats by inhibiting osteoclastogenesis via spleen tyrosine kinase

JTE-852, a novel spleen tyrosine kinase inhibitor, blocks mediator secretion from mast cells with immunoglobulin E crosslinking

(2017) Toshinobu Kato et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Periarticular Bone Loss in Arthritis Is Induced by Autoantibodies Against Citrullinated Vimentin

(2017) Cecilia Engdahl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

RANKL: A therapeutic target for bone destruction in rheumatoid arthritis

(2017) Sakae Tanaka et al.   Modern Rheumatology

Tetrandrine ameliorates collagen-induced arthritis in mice by restoring the balance between Th17 and Treg cells via the aryl hydrocarbon receptor

(2016) Xusheng Yuan et al.   BIOCHEMICAL PHARMACOLOGY

Cartilage damage and bone erosion are more prominent determinants of functional impairment in longstanding experimental arthritis than synovial inflammation

(2016) Silvia Hayer et al.   Disease Models & Mechanisms

Denosumab: targeting the RANKL pathway to treat rheumatoid arthritis

(2016) Yahui Grace Chiu et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Nicotinamide phosphoribosyltransferase inhibits receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation in vitro

(2016) Jong Min Baek et al.   Molecular Medicine Reports

Sirtuin 3 (SIRT3) maintains bone homeostasis by regulating AMPK-PGC-1β axis in mice

(2016) Jeong-Eun Huh et al.   Scientific Reports

DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk

(2016) Daniela Justa-Schuch et al.   eLife

Decursin inhibits osteoclastogenesis by downregulating NFATc1 and blocking fusion of pre-osteoclasts

(2015) Kwang-Jin Kim et al.   BONE

WHI-131 Promotes Osteoblast Differentiation and Prevents Osteoclast Formation and Resorption in Mice

(2015) Yoon-Hee Cheon et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Harpagoside Inhibits RANKL-Induced Osteoclastogenesis via Syk-Btk-PLCγ2-Ca2+ Signaling Pathway and Prevents Inflammation-Mediated Bone Loss

(2015) Ju-Young Kim et al.   JOURNAL OF NATURAL PRODUCTS

Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang andStephania tetrandra S. Mooreextracts

(2015) Xiaoli Wang et al.   JOURNAL OF SEPARATION SCIENCE

Osteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone Loss

(2015) Tania N. Crotti et al.   Journal of Immunology Research

Small Molecule Substrate Phosphorylation Site Inhibitors of Protein Kinases: Approaches and Challenges

(2014) Meghan E. Breen et al.   ACS Chemical Biology

RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis

(2014) Susan Li et al.   JOURNAL OF CLINICAL INVESTIGATION

High glucose inhibits receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via downregulation of v-ATPase V0 subunit d2 and dendritic cell-specific transmembrane protein

(2014) JUAN XU et al.   Molecular Medicine Reports

Getting Syk: spleen tyrosine kinase as a therapeutic target

(2014) Robert L. Geahlen   TRENDS IN PHARMACOLOGICAL SCIENCES

Lipoproteins are an important bacterial component responsible for bone destruction through the induction of osteoclast differentiation and activation

(2013) Jiseon Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Norisoboldine Suppresses Osteoclast Differentiation through Preventing the Accumulation of TRAF6-TAK1 Complexes and Activation of MAPKs/NF-κB/c-Fos/NFATc1 Pathways

(2013) Zhi-feng Wei et al.   PLoS One

Combination of Tumor Necrosis Factor α and Interleukin-6 Induces Mouse Osteoclast-like Cells With Bone Resorption Activity Both In Vitro and In Vivo

(2013) Kazuhiro Yokota et al.   Arthritis & Rheumatology

Tetrandrine Prevents Bone Loss in Sciatic-Neurectomized Mice and Inhibits Receptor Activator of Nuclear Factor ^|^#954;B Ligand-Induced Osteoclast Differentiation

(2012) Tatsuo Takahashi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Fyn positively regulates the activation of DAP12 and FcRγ-mediated costimulatory signals by RANKL during osteoclastogenesis

(2012) H.S. Kim et al.   CELLULAR SIGNALLING

Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-κB, and AP-1 activation in RAW264.7 cells

(2012) Chandagirikoppal V. Kavitha et al.   MOLECULAR CARCINOGENESIS

The osteoclast and its unique cytoskeleton

(2011) Steven L. Teitelbaum   Annals of the New York Academy of Sciences

Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways

(2010) Chenghai Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone Damage in Rheumatoid Arthritis: Mechanistic Insights and Approaches to Prevention

(2010) Sougata Karmakar et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

IL-10 Suppresses Calcium-Mediated Costimulation of Receptor Activator NF- B Signaling during Human Osteoclast Differentiation by Inhibiting TREM-2 Expression

(2009) K.-H. Park-Min et al.   JOURNAL OF IMMUNOLOGY

Establishment of a liquid chromatographic/mass spectrometry method for quantification of tetrandrine in rat plasma and its application to pharmacokinetic study

(2008) Naining Song et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS