Norisoboldine Suppresses Osteoclast Differentiation through Preventing the Accumulation of TRAF6-TAK1 Complexes and Activation of MAPKs/NF-κB/c-Fos/NFATc1 Pathways

Ginsenoside Rb1 inhibits osteoclastogenesis by modulating NF-κB and MAPKs pathways

(2012) Binbin Cheng et al.   FOOD AND CHEMICAL TOXICOLOGY

Norisoboldine inhibits the production of interleukin-6 in fibroblast-like synoviocytes from adjuvant arthritis rats through PKC/MAPK/NF-κB-p65/CREB pathways

(2012) Zhifeng Wei et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Therapeutic targeting of osteoclast function and pathways

(2011) Matthew L Broadhead et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis

(2011) Tobias Braun et al.   ARTHRITIS RESEARCH & THERAPY

Role of NF-κB in the skeleton

(2010) Deborah Veis Novack   CELL RESEARCH

Osteoclasts in arthritis and Th17 cell development

(2010) Kazuo Okamoto et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The TAK1–TRAF6 signalling pathway

(2010) Marene Landström   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Rheumatoid arthritis and periodontal disease

(2010) Jean-Marie Berthelot et al.   JOINT BONE SPINE

Therapeutic effect of norisoboldine, an alkaloid isolated from Radix Linderae, on collagen-induced arthritis in mice

(2010) Y. Luo et al.   PHYTOMEDICINE

Bone Damage in Rheumatoid Arthritis: Mechanistic Insights and Approaches to Prevention

(2010) Sougata Karmakar et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Denosumab prevents metacarpal shaft cortical bone loss in patients with erosive rheumatoid arthritis

(2010) John T. Sharp et al.   ARTHRITIS CARE & RESEARCH

NFATc1: Functions in osteoclasts

(2009) Qingxiao Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway

(2009) M. S. Lee et al.   JOURNAL OF IMMUNOLOGY

Denosumab for joints and bones

(2009) E. Michael Lewiecki   Current Rheumatology Reports

Cathepsin G Enhances Mammary Tumor-Induced Osteolysis by Generating Soluble Receptor Activator of Nuclear Factor- B Ligand

(2008) T. J. Wilson et al.   CANCER RESEARCH

JNK/c-Jun Signaling Mediates an Anti-Apoptotic Effect of RANKL in Osteoclasts

(2008) Fumiyo Ikeda et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Lipopolysaccharide suppresses RANK gene expression in macrophages by down-regulating PU.1 and MITF

(2008) Junko Ishii et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL

(2008) Matthew C. Walsh et al.   PLoS One