Astroglial 5-HT2B receptor in mood disorders

Physiology of Astroglia

(2018) Alexei Verkhratsky et al.   PHYSIOLOGICAL REVIEWS

Bi-phasic regulation of glycogen content in astrocytes via Cav-1/PTEN/PI3K/AKT/GSK-3β pathway by fluoxetine

(2017) Qiufang Bai et al.   PSYCHOPHARMACOLOGY

Aberrant iPSC-derived human astrocytes in Alzheimer's disease

(2017) V C Jones et al.   Cell Death & Disease

Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein

(2017) Anna-Lena Hallmann et al.   Scientific Reports

Targeting astrocytes in bipolar disorder

(2016) Liang Peng et al.   Expert Review of Neurotherapeutics

Principles of sodium homeostasis and sodium signalling in astroglia

(2016) Christine R. Rose et al.   GLIA

Targeting astrocytes in bipolar disorder

(2016) Liang Peng et al.   Expert Review of Neurotherapeutics

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Targeting astrocytes in major depression

(2015) Liang Peng et al.   Expert Review of Neurotherapeutics

Cell type-specific in vivo expression of genes encoding signalling molecules in the brain in response to chronic mild stress and chronic treatment with fluoxetine

(2015) Lu Dong et al.   PSYCHOPHARMACOLOGY

Decrease of gene expression of astrocytic 5-HT2B receptors parallels development of depressive phenotype in a mouse model of Parkinson’s disease

(2015) Xique Zhang et al.   Frontiers in Cellular Neuroscience

Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift

(2015) Leif Hertz et al.   Frontiers in Behavioral Neuroscience

Targeting astrocytes in major depression

(2015) Liang Peng et al.   Expert Review of Neurotherapeutics

Editorial (Thematic Issue: Neuroglia as a Central Element of Neurological Diseases: An Underappreciated Target for Therapeutic Intervention)

(2014) Liang Peng et al.   Current Neuropharmacology

Fluoxetine and all other SSRIs are 5-HT2B Agonists - Importance for their Therapeutic Effects

(2014) Liang Peng et al.   Current Neuropharmacology

Phenotypic Heterogeneity and Plasticity of Isocortical and Hippocampal Astrocytes in the Human Brain

(2014) A. A. Sosunov et al.   JOURNAL OF NEUROSCIENCE

α1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice

(2013) Fengfei Ding et al.   CELL CALCIUM

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

(2013) Grazyna Rajkowska et al.   CURRENT DRUG TARGETS

The Pro-inflammatory Cytokine TNF-α Regulates the Activity and Expression of the Serotonin Transporter (SERT) in Astrocytes

(2013) Sandra Malynn et al.   NEUROCHEMICAL RESEARCH

The glial perspective of autism spectrum disorders

(2013) Fares Zeidán-Chuliá et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Astrogliopathology

(2013) Alexei Verkhratsky et al.   NEUROSCIENTIST

Depression in Parkinson's disease: diagnosis and treatment

(2012) Flavio Henrique de Rezende Costa et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Astrocytes as a 5-HT2B-Mediated SERT-Independent SSRI Target, Slowly Altering Depression-Associated Genes and Function

(2012) Leif Hertz et al.   Current Signal Transduction Therapy

Continuous GSK-3β overexpression in the hippocampal dentate gyrus induces prodepressant-like effects and increases sensitivity to chronic mild stress in mice

(2012) Kerang Zhang et al.   JOURNAL OF AFFECTIVE DISORDERS

Cell Type-Specific Gene Expression and Editing Responses to Chronic Fluoxetine Treatment in the In Vivo Mouse Brain and Their Relevance for Stress-Induced Anhedonia

(2012) Baoman Li et al.   NEUROCHEMICAL RESEARCH

Sodium dynamics: another key to astroglial excitability?

(2012) Sergei Kirischuk et al.   TRENDS IN NEUROSCIENCES

Caveolins: targeting pro-survival signaling in the heart and brain

(2012) Creed M. Stary et al.   Frontiers in Physiology

Protein levels of β-catenin and activation state of glycogen synthase kinase-3β in major depression. A study with postmortem prefrontal cortex

(2011) Félicien Karege et al.   JOURNAL OF AFFECTIVE DISORDERS

A review on animal models for screening potential anti-stress agents

(2011) Amteshwar Singh Jaggi et al.   NEUROLOGICAL SCIENCES

Pathologic Caveolin-1 Regulation of PTEN in Idiopathic Pulmonary Fibrosis

(2010) Hong Xia et al.   AMERICAN JOURNAL OF PATHOLOGY

Antidepressants act on glial cells: SSRIs and serotonin elicit astrocyte calcium signaling in the mouse prefrontal cortex

(2010) Carola G. Schipke et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Serotonin increases ERK1/2 phosphorylation in astrocytes by stimulation of 5-HT2B and 5-HT2C receptors

(2010) Baoman Li et al.   NEUROCHEMISTRY INTERNATIONAL

Adrenoceptors in brain: Cellular gene expression and effects on astrocytic metabolism and [Ca2+]i

(2010) Leif Hertz et al.   NEUROCHEMISTRY INTERNATIONAL

5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional ‘serotonin-specific reuptake inhibitors’

(2010) Shiquen Zhang et al.   Neuron Glia Biology

Light and Electron Microscopy Study of Glycogen Synthase Kinase-3β in the Mouse Brain

(2010) Emma Perez-Costas et al.   PLoS One

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation

(2008) Baoman Li et al.   PSYCHOPHARMACOLOGY